STRINGSTRING
Tint_0580 Tint_0580 Tint_2715 Tint_2715 Tint_2716 Tint_2716 Tint_2720 Tint_2720 bioB bioB Tint_2723 Tint_2723 vapC-3 vapC-3 Tint_2725 Tint_2725 Tint_2728 Tint_2728 aceK aceK Tint_2732 Tint_2732
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tint_0580KEGG: app:CAP2UW1_0244 biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: protein of unknown function DUF559; biotin/lipoate A/B protein ligase; biotin protein ligase domain protein. (445 aa)
Tint_2715PFAM: protein of unknown function DUF1289; KEGG: mpt:Mpe_A3352 hypothetical protein. (72 aa)
Tint_2716PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: aav:Aave_4348 YbaK/prolyl-tRNA synthetase associated region. (170 aa)
Tint_2720KEGG: vap:Vapar_4720 putative transmembrane protein. (225 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (342 aa)
Tint_2723PFAM: DinB family protein; KEGG: ajs:Ajs_3762 DinB family protein. (175 aa)
vapC-3PilT protein domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (132 aa)
Tint_2725PFAM: Protein of unknown function DUF2191; KEGG: noc:Noc_0414 hypothetical protein. (102 aa)
Tint_2728PFAM: DSBA oxidoreductase; KEGG: app:CAP2UW1_4329 DsbA oxidoreductase. (201 aa)
aceK(Isocitrate dehydrogenase (NADP(+))) kinase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (604 aa)
Tint_2732PFAM: aminotransferase class V; KEGG: rfr:Rfer_3691 aminotransferase, class V. (384 aa)
Your Current Organism:
Thiomonas intermedia
NCBI taxonomy Id: 75379
Other names: T. intermedia K12, Thiobacillus intermedius K12, Thiomonas intermedia K12, Thiomonas intermedia str. K12, Thiomonas intermedia strain K12
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.