STRINGSTRING
queA queA tgt tgt Tint_0536 Tint_0536 Tint_0537 Tint_0537 Tint_0538 Tint_0538 Tint_0539 Tint_0539 Tint_0735 Tint_0735 Tint_0737 Tint_0737 Tint_0738 Tint_0738 Tint_0742 Tint_0742 mnmA mnmA nudJ nudJ Tint_1107 Tint_1107 Tint_1333 Tint_1333 Tint_1334 Tint_1334 Tint_1335 Tint_1335 Tint_1336 Tint_1336 Tint_1756 Tint_1756 tadA tadA Tint_1758 Tint_1758 queG queG Tint_1798 Tint_1798 queF queF Tint_1862 Tint_1862 Tint_1863 Tint_1863 Tint_2246 Tint_2246 tsaD tsaD Tint_2293 Tint_2293
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
queAS-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (406 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (379 aa)
Tint_0536KEGG: ttj:TTHA1701 hypothetical protein. (99 aa)
Tint_0537KEGG: lch:Lcho_0372 phage SPO1 DNA polymerase-related protein; TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily. (288 aa)
Tint_0538KEGG: mpt:Mpe_A0302 SSU ribosomal protein S18P alanine acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase. (184 aa)
Tint_0539PFAM: peptidase M22 glycoprotease; KEGG: mfa:Mfla_0412 peptidase M22, glycoprotease. (275 aa)
Tint_0735TIGRFAM: carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; KEGG: dac:Daci_1812 carboxyl-terminal protease; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S41A family. (500 aa)
Tint_0737Rhodanese domain protein; KEGG: ctt:CtCNB1_3888 sulfate permease andrelated transporter; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein. (136 aa)
Tint_0738Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (87 aa)
Tint_0742KEGG: mpt:Mpe_A3226 hypothetical protein. (152 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (368 aa)
nudJPFAM: NUDIX hydrolase; KEGG: vap:Vapar_0388 NUDIX hydrolase; Belongs to the Nudix hydrolase family. NudJ subfamily. (162 aa)
Tint_1107PFAM: Uracil-DNA glycosylase superfamily; KEGG: tgr:Tgr7_1908 hypothetical protein. (227 aa)
Tint_1333PFAM: peptidase M50; KEGG: aav:Aave_3710 peptidase M50. (219 aa)
Tint_1334KEGG: lch:Lcho_2584 SUA5/YciO/YrdC/YwlC family protein; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; Belongs to the SUA5 family. (211 aa)
Tint_1335PHP domain protein; KEGG: aav:Aave_3707 phosphotransferase domain-containing protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein. (283 aa)
Tint_1336PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: bgl:bglu_1g29220 hypothetical protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (162 aa)
Tint_1756KEGG: bav:BAV1993 muramoyltetrapeptide carboxypeptidase; PFAM: peptidase U61 LD-carboxypeptidase A. (316 aa)
tadACMP/dCMP deaminase zinc-binding protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (187 aa)
Tint_1758KEGG: dia:Dtpsy_1591 hypothetical protein. (72 aa)
queGIron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (378 aa)
Tint_1798PFAM: protein of unknown function UPF0079; KEGG: dac:Daci_5126 hypothetical protein. (174 aa)
queF7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (139 aa)
Tint_1862Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (226 aa)
Tint_1863KEGG: azo:azo0588 hypothetical protein. (203 aa)
Tint_2246PFAM: nucleoside recognition domain protein; KEGG: pap:PSPA7_6276 hypothetical protein. (410 aa)
tsaDMetalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (342 aa)
Tint_2293PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: lch:Lcho_2887 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Belongs to the peptidase S11 family. (493 aa)
Your Current Organism:
Thiomonas intermedia
NCBI taxonomy Id: 75379
Other names: T. intermedia K12, Thiobacillus intermedius K12, Thiomonas intermedia K12, Thiomonas intermedia str. K12, Thiomonas intermedia strain K12
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