STRINGSTRING
gpmA gpmA pgi pgi Tint_0140 Tint_0140 Tint_0284 Tint_0284 Tint_0285 Tint_0285 Tint_0437 Tint_0437 tpiA tpiA Tint_2122 Tint_2122 Tint_1700 Tint_1700 Tint_1699 Tint_1699 Tint_1696 Tint_1696 zwf zwf aceK aceK Tint_2569 Tint_2569
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (235 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: bpt:Bpet4022 hypothetical protein; Belongs to the GPI family. (502 aa)
Tint_0140TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: mag:amb0512 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
Tint_0284KEGG: rme:Rmet_4670 respiratory-chain NADH dehydrogenase, subunit 1. (325 aa)
Tint_0285KEGG: rfr:Rfer_3290 hydrogenase 4 membrane component. (273 aa)
Tint_0437Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (809 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa)
Tint_2122Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (795 aa)
Tint_1700KEGG: hna:Hneap_1792 hydrogenase 4 membrane component (E). (226 aa)
Tint_1699PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: hna:Hneap_1793 respiratory-chain NADH dehydrogenase subunit 1. (314 aa)
Tint_1696PFAM: Phosphoglycerate mutase; KEGG: bte:BTH_I2758 phosphohistidine phosphatase SixA. (171 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (496 aa)
aceK(Isocitrate dehydrogenase (NADP(+))) kinase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (604 aa)
Tint_2569TIGRFAM: L-serine dehydratase 1; KEGG: mpt:Mpe_A1429 L-serine ammonia-lyase; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. (476 aa)
Your Current Organism:
Thiomonas intermedia
NCBI taxonomy Id: 75379
Other names: T. intermedia K12, Thiobacillus intermedius K12, Thiomonas intermedia K12, Thiomonas intermedia str. K12, Thiomonas intermedia strain K12
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.