STRINGSTRING
Tint_2717 Tint_2717 gcvP gcvP gcvH gcvH Tint_2573 Tint_2573 dnaA dnaA Tint_0151 Tint_0151 Tint_0169 Tint_0169 Tint_0725 Tint_0725 Tint_0869 Tint_0869 kynA kynA kynU kynU kynB kynB Tint_1003 Tint_1003 Tint_1345 Tint_1345 dadA dadA Tint_1712 Tint_1712 Tint_2455 Tint_2455
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tint_2717PFAM: pyruvate carboxyltransferase; KEGG: cti:RALTA_A0129 hydroxymethylglutaryl-CoA lyase. (315 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (961 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (124 aa)
Tint_2573KEGG: aav:Aave_3145 glycine cleavage system T protein; TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel. (386 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (484 aa)
Tint_0151Amidohydrolase; KEGG: bav:BAV1013 X-Pro dipeptidase; manually curated; PFAM: amidohydrolase; Twin-arginine translocation pathway, signal sequence, subgroup. (496 aa)
Tint_0169Agmatinase; KEGG: mpt:Mpe_A1890 agmatinase; TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; Belongs to the arginase family. (317 aa)
Tint_0725Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1352 aa)
Tint_0869PFAM: histidine triad (HIT) protein; KEGG: pna:Pnap_0705 histidine triad (HIT) protein. (116 aa)
kynATryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (286 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (427 aa)
kynBArylformamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. (212 aa)
Tint_1003TIGRFAM: phenylalanine-4-hydroxylase; KEGG: mpt:Mpe_A0347 phenylalanine 4-monooxygenase; PFAM: Aromatic amino acid hydroxylase-like. (288 aa)
Tint_13452-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (432 aa)
dadAFAD dependent oxidoreductase; Oxidative deamination of D-amino acids. (430 aa)
Tint_1712PFAM: histidine triad (HIT) protein; KEGG: swo:Swol_1000 hypothetical protein. (126 aa)
Tint_2455PFAM: FAD dependent oxidoreductase; KEGG: bja:bll4301 putative oxidoreductase protein. (347 aa)
Your Current Organism:
Thiomonas intermedia
NCBI taxonomy Id: 75379
Other names: T. intermedia K12, Thiobacillus intermedius K12, Thiomonas intermedia K12, Thiomonas intermedia str. K12, Thiomonas intermedia strain K12
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