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Tint_2388 | 3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (411 aa) | ||||
Tint_1700 | KEGG: hna:Hneap_1792 hydrogenase 4 membrane component (E). (226 aa) | ||||
eno-2 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa) | ||||
Tint_1713 | PFAM: Phosphoglycerate mutase; KEGG: ttr:Tter_2494 phosphoglycerate mutase. (205 aa) | ||||
Tint_1734 | PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pzu:PHZ_p0173 acyl-CoA dehydrogenase. (543 aa) | ||||
ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (427 aa) | ||||
Tint_1874 | PFAM: aminotransferase class-III; KEGG: bte:BTH_I1505 omega amino acid--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa) | ||||
acsA | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (659 aa) | ||||
Tint_2095 | Manually curated; TIGRFAM: amino acid adenylation domain protein; KEGG: vap:Vapar_3184 amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; aminotransferase class-III. (2469 aa) | ||||
Tint_2096 | KEGG: vap:Vapar_3185 amino acid adenylation domain protein; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding. (1650 aa) | ||||
gloB | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (272 aa) | ||||
Tint_2122 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (795 aa) | ||||
fabZ | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (149 aa) | ||||
dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (401 aa) | ||||
Tint_2191 | Pyruvate kinase; KEGG: app:CAP2UW1_1860 pyruvate kinase; PFAM: Pyruvate kinase barrel. (620 aa) | ||||
tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa) | ||||
Tint_2271 | Hypothetical protein; KEGG: lch:Lcho_1498 PIG3 family NAD(P)H quinone oxidoreductase; TIGRFAM: NAD(P)H quinone oxidoreductase, PIG3 family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein. (326 aa) | ||||
eno-3 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) | ||||
Tint_2290 | PFAM: protein of unknown function DUF162; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: rpi:Rpic_1934 iron-sulfur cluster binding protein. (473 aa) | ||||
Tint_2302 | propionate/CoA ligase; KEGG: rpi:Rpic_2037 propionyl-CoA synthetase; TIGRFAM: propionate/CoA ligase; PFAM: AMP-dependent synthetase and ligase. (630 aa) | ||||
Tint_2306 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (461 aa) | ||||
Tint_2307 | 2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (906 aa) | ||||
accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (291 aa) | ||||
prpB | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (296 aa) | ||||
Tint_2346 | 2-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein; manually curated; KEGG: bpt:Bpet1812 2-methylcitrate dehydratase; TIGRFAM: 2-methylcitrate dehydratase. (483 aa) | ||||
Tint_2370 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (163 aa) | ||||
Tint_2371 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa) | ||||
acpS | Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (133 aa) | ||||
acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (79 aa) | ||||
Tint_2391 | KEGG: rme:Rmet_2429 [acyl-carrier-protein] S-malonyltransferase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase. (311 aa) | ||||
fabH | 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (325 aa) | ||||
plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (366 aa) | ||||
Tint_2518 | PFAM: AMP-dependent synthetase and ligase; KEGG: vap:Vapar_0394 AMP-dependent synthetase and ligase. (556 aa) | ||||
aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (290 aa) | ||||
Tint_2596 | PFAM: Methyltransferase type 11; KEGG: mpt:Mpe_A3183 biotin synthesis protein BioC. (313 aa) | ||||
Tint_2601 | PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; KEGG: reh:H16_A0461 3-hydroxyacyl-CoA dehydrogenase. (799 aa) | ||||
Tint_2602 | PFAM: acyl-CoA dehydrogenase domain protein; KEGG: rso:RSc0473 putative acyl-CoA dehydrogenase oxidoreductase protein. (598 aa) | ||||
Tint_2641 | PFAM: FAD linked oxidase domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: pol:Bpro_0858 FAD linked oxidase-like. (1330 aa) | ||||
fabA | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (171 aa) | ||||
Tint_2709 | KEGG: dar:Daro_4039 beta-lactamase-like. (343 aa) | ||||
bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (342 aa) | ||||
Tint_2726 | KEGG: dac:Daci_5973 propionyl-CoA carboxylase; PFAM: carboxyl transferase. (535 aa) | ||||
Tint_2727 | PFAM: AMP-dependent synthetase and ligase; KEGG: pol:Bpro_4161 AMP-binding domain protein. (567 aa) | ||||
Tint_2729 | PFAM: acyl-CoA dehydrogenase domain protein; KEGG: lch:Lcho_4207 acyl-CoA dehydrogenase domain-containing protein. (375 aa) | ||||
aceK | (Isocitrate dehydrogenase (NADP(+))) kinase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (604 aa) | ||||
Tint_2733 | PFAM: acyl-CoA dehydrogenase domain protein; KEGG: ajs:Ajs_3779 isovaleryl-CoA dehydrogenase. (392 aa) | ||||
Tint_2736 | KEGG: rfr:Rfer_3844 beta-lactamase-like. (351 aa) | ||||
Tint_2796 | TIGRFAM: malate synthase A; KEGG: rpf:Rpic12D_1302 malate synthase A; PFAM: Malate synthase family protein; Belongs to the malate synthase family. (528 aa) | ||||
lipA | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (321 aa) | ||||
Tint_2858 | KEGG: bcj:BCAL1949 glyoxylate carboligase; TIGRFAM: glyoxylate carboligase; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; Belongs to the TPP enzyme family. (582 aa) | ||||
ubiC | Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (183 aa) | ||||
Tint_2986 | PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: tmz:Tmz1t_0853 fumarylacetoacetate (FAA) hydrolase. (337 aa) | ||||
Tint_2994 | PFAM: monooxygenase FAD-binding; KEGG: eba:ebA3297 FAD-dependent oxidoreductase. (558 aa) | ||||
Tint_2995 | KEGG: vei:Veis_4551 beta-lactamase domain-containing protein. (318 aa) | ||||
Tint_2997 | KEGG: vap:Vapar_1226 phenylacetic acid degradation protein PaaN; TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: MaoC domain protein dehydratase; Aldehyde Dehydrogenase. (684 aa) | ||||
Tint_3001 | KEGG: dac:Daci_0813 phenylacetate-CoA oxygenase, PaaJ subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59. (171 aa) | ||||
Tint_3002 | KEGG: vap:Vapar_1233 phenylacetate-CoA oxygenase, PaaI subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein. (257 aa) | ||||
Tint_3003 | KEGG: vap:Vapar_1234 phenylacetate-CoA oxygenase, PaaH subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit; PFAM: phenylacetic acid degradation B. (105 aa) | ||||
Tint_3004 | KEGG: lch:Lcho_3574 phenylacetate-CoA oxygenase subunit PaaA; TIGRFAM: phenylacetate-CoA oxygenase, PaaG subunit; PFAM: phenylacetic acid catabolic family protein. (335 aa) | ||||
Tint_3005 | phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (440 aa) | ||||
Tint_3006 | KEGG: lch:Lcho_2404 phenylacetic acid degradation protein PaaD; TIGRFAM: phenylacetic acid degradation protein PaaD; PFAM: thioesterase superfamily protein. (161 aa) | ||||
Tint_3007 | PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: azo:azo0301 3-hydroxy-acyl-CoA dehydrogenase. (490 aa) | ||||
Tint_3008 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mpt:Mpe_A0984 short chain enoyl-CoA hydratase / enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (265 aa) | ||||
gph | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (233 aa) | ||||
Tint_3153 | KEGG: dar:Daro_4039 beta-lactamase-like. (344 aa) | ||||
Tint_3155 | KEGG: hna:Hneap_0555 beta-lactamase domain protein. (354 aa) | ||||
Tint_3173 | Amino acid adenylation domain protein; KEGG: amr:AM1_A0235 peptide synthetase, putative; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding. (2165 aa) | ||||
Tint_0005 | KEGG: vap:Vapar_4072 formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (977 aa) | ||||
glk | TIGRFAM: glucokinase; KEGG: cvi:CV_0147 glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. (326 aa) | ||||
edd | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (631 aa) | ||||
Tint_0027 | TIGRFAM: lactoylglutathione lyase; KEGG: pol:Bpro_3549 glyoxalase I; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. (129 aa) | ||||
Tint_0057 | KEGG: pca:Pcar_1486 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region. (467 aa) | ||||
anmK | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (370 aa) | ||||
Tint_0139 | KEGG: pna:Pnap_1985 phosphoglycolate phosphatase; TIGRFAM: phosphoglycolate phosphatase; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase. (231 aa) | ||||
pgk | KEGG: cti:RALTA_A0522 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (401 aa) | ||||
Tint_0142 | Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa) | ||||
Tint_0151 | Amidohydrolase; KEGG: bav:BAV1013 X-Pro dipeptidase; manually curated; PFAM: amidohydrolase; Twin-arginine translocation pathway, signal sequence, subgroup. (496 aa) | ||||
Tint_0169 | Agmatinase; KEGG: mpt:Mpe_A1890 agmatinase; TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; Belongs to the arginase family. (317 aa) | ||||
Tint_0179 | PFAM: aminotransferase class-III; KEGG: lch:Lcho_1738 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (466 aa) | ||||
Tint_0224 | PFAM: Phosphoglycerate mutase; KEGG: pol:Bpro_4091 phosphoglycerate mutase. (216 aa) | ||||
Tint_0248 | PFAM: acyl-CoA dehydrogenase domain protein; KEGG: mpt:Mpe_A3170 glutaryl-CoA dehydrogenase. (393 aa) | ||||
Tint_0284 | KEGG: rme:Rmet_4670 respiratory-chain NADH dehydrogenase, subunit 1. (325 aa) | ||||
Tint_0285 | KEGG: rfr:Rfer_3290 hydrogenase 4 membrane component. (273 aa) | ||||
ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (343 aa) | ||||
Tint_0349 | PFAM: thioesterase superfamily protein; KEGG: bvi:Bcep1808_2816 thioesterase superfamily protein. (134 aa) | ||||
accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa) | ||||
Tint_0437 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (809 aa) | ||||
Tint_0447 | PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: mba:Mbar_A0176 aldolase. (304 aa) | ||||
eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa) | ||||
Tint_0482 | PFAM: protein of unknown function DUF162; KEGG: bpr:GBP346_A2993 hypothetical protein. (219 aa) | ||||
Tint_0592 | PFAM: acyl-coA-binding protein ACBP; KEGG: har:HEAR0806 putative acyl-CoA-binding protein (ACBP). (91 aa) | ||||
Tint_0605 | PFAM: FAD linked oxidase domain protein; KEGG: azo:azo1000 glycolate oxidase FAD binding subunit. (374 aa) | ||||
Tint_0606 | PFAM: FAD linked oxidase domain protein; KEGG: vap:Vapar_0222 FAD linked oxidase domain protein. (497 aa) | ||||
Tint_0616 | PFAM: Phosphoglycerate mutase; KEGG: rpd:RPD_0651 phosphoglycerate mutase. (225 aa) | ||||
Tint_0626 | PFAM: FAD linked oxidase domain protein; KEGG: mpt:Mpe_A3774 putative oxidoreductase. (468 aa) | ||||
Tint_0688 | PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pol:Bpro_2961 acyl-CoA dehydrogenase-like. (405 aa) | ||||
Tint_0689 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: aav:Aave_3074 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (220 aa) | ||||
gpmA | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (235 aa) | ||||
Tint_0760 | PFAM: SlyX family protein; KEGG: bav:BAV1796 protein SlyX. (75 aa) | ||||
Tint_0779 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (399 aa) | ||||
Tint_0807 | TIGRFAM: pyruvate kinase; KEGG: mpt:Mpe_A0290 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (477 aa) | ||||
Tint_0843 | PFAM: AMP-dependent synthetase and ligase; KEGG: bpt:Bpet4737 putative phenylacetate-CoA ligase. (437 aa) | ||||
Tint_0849 | PFAM: AMP-dependent synthetase and ligase; KEGG: aav:Aave_0787 AMP-dependent synthetase and ligase. (651 aa) | ||||
Tint_0943 | PFAM: AMP-dependent synthetase and ligase; KEGG: app:CAP2UW1_2247 AMP-dependent synthetase and ligase. (573 aa) | ||||
panC | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (281 aa) | ||||
panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (286 aa) | ||||
Tint_0990 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (334 aa) | ||||
kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (427 aa) | ||||
kynB | Arylformamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. (212 aa) | ||||
Tint_1005 | PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: tmz:Tmz1t_0853 fumarylacetoacetate (FAA) hydrolase. (337 aa) | ||||
pgi | PFAM: phosphoglucose isomerase (PGI); KEGG: bpt:Bpet4022 hypothetical protein; Belongs to the GPI family. (502 aa) | ||||
Tint_1101 | PFAM: MaoC domain protein dehydratase; KEGG: mpt:Mpe_A3698 MaoC-related protein. (169 aa) | ||||
Tint_1249 | PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: pap:PSPA7_2767 hypothetical protein. (234 aa) | ||||
Tint_1283 | PFAM: AMP-dependent synthetase and ligase; KEGG: dac:Daci_3306 acyl-CoA synthetase. (542 aa) | ||||
Tint_1285 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bpr:GBP346_A2617 enoyl-[acyl-carrier-protein] reductase [NADH] (nadh-dependent enoyl-acp reductase). (269 aa) | ||||
Tint_1344 | TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; KEGG: reu:Reut_A2047 2-oxoglutarate dehydrogenase E1 component; PFAM: Transketolase central region; dehydrogenase E1 component. (950 aa) | ||||
Tint_1346 | KEGG: bpt:Bpet1834 dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region. (477 aa) | ||||
Tint_1350 | PFAM: AMP-dependent synthetase and ligase; KEGG: ajs:Ajs_3136 AMP-dependent synthetase and ligase. (547 aa) | ||||
Tint_1353 | PFAM: acyl-CoA dehydrogenase domain protein; KEGG: mpt:Mpe_A1298 putative acyl-CoA dehydrogenase oxidoreductase protein. (594 aa) | ||||
Tint_1359 | PFAM: FAD linked oxidase domain protein; KEGG: mpt:Mpe_A1420 putative oxidoreductase protein. (476 aa) | ||||
Tint_1393 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; KEGG: cti:RALTA_A2531 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. (416 aa) | ||||
Tint_1416 | KEGG: tgr:Tgr7_2385 hypothetical protein. (83 aa) | ||||
Tint_1417 | PFAM: AMP-dependent synthetase and ligase; KEGG: sme:SM_b20650 putative long-chain fatty-acid-CoA ligase protein. (515 aa) | ||||
Tint_1576 | PFAM: MaoC domain protein dehydratase; KEGG: bbt:BBta_3583 NodN-like protein. (75 aa) | ||||
Tint_1585 | PFAM: Amidohydrolase 3; KEGG: dac:Daci_5666 amidohydrolase 3. (556 aa) | ||||
Tint_1587 | PFAM: AMP-dependent synthetase and ligase; KEGG: bpy:Bphyt_5034 acyl-CoA synthetase. (558 aa) | ||||
Tint_1589 | PFAM: acyl-CoA dehydrogenase domain protein; KEGG: rce:RC1_1018 acyl-CoA dehydrogenase, putative. (413 aa) | ||||
Tint_1593 | PFAM: acyl-CoA dehydrogenase domain protein; KEGG: rfr:Rfer_2384 acyl-CoA dehydrogenase-like. (609 aa) | ||||
Tint_1595 | PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: cti:RALTA_A1467 multifunctional: 3-hydroxybutyryl-CoA epimerase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, enoyl-CoA hydratase (N-terminal); 3-hydroxyacyl-CoA dehydrogenase (C-terminal). (697 aa) | ||||
Tint_1597 | PFAM: alpha/beta hydrolase fold; KEGG: rme:Rmet_1845 alpha/beta hydrolase fold. (296 aa) | ||||
merA | Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (556 aa) | ||||
ispH | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (327 aa) | ||||
Tint_1662 | KEGG: azo:azo2149 acetoacetyl-CoA synthetase; TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase. (670 aa) | ||||
Tint_1663 | PFAM: thioesterase superfamily protein; KEGG: lch:Lcho_2065 thioesterase superfamily protein. (145 aa) | ||||
ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (160 aa) | ||||
ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (245 aa) | ||||
Tint_1699 | PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: hna:Hneap_1793 respiratory-chain NADH dehydrogenase subunit 1. (314 aa) |