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| | Tint_2089 | KEGG: pnu:Pnuc_0792 rhodanese domain-containing protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein. (328 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (219 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (300 aa) |
| | Tint_0725 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1352 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (430 aa) |
| | Tint_0597 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (367 aa) |
| | Tint_0585 | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (264 aa) |
| | glmS | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (611 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (304 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (286 aa) |
| | Tint_1870 | KEGG: pol:Bpro_1792 chorismate mutase / prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein. (365 aa) |
| | Tint_1868 | PFAM: Prephenate dehydrogenase; KEGG: vap:Vapar_1616 prephenate dehydrogenase. (304 aa) |
| | cmk | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. (658 aa) |
| | Tint_1849 | PFAM: aminotransferase class I and II; KEGG: mpt:Mpe_A2293 aromatic amino acid aminotransferase. (401 aa) |
| | Tint_1833 | KEGG: lch:Lcho_0664 cysteine synthase B; TIGRFAM: cysteine synthase B; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. (300 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (532 aa) |
| | Tint_1752 | KEGG: aav:Aave_2485 succinyldiaminopimelate transaminase; TIGRFAM: succinyldiaminopimelate transaminase; PFAM: aminotransferase class I and II. (403 aa) |
| | dapD | TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; KEGG: mpt:Mpe_A1806 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (273 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (382 aa) |
| | carA | KEGG: mpt:Mpe_A1261 carbamoyl-phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. (383 aa) |
| | carB | KEGG: pol:Bpro_2678 carbamoyl-phosphate synthase large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; Belongs to the CarB family. (1074 aa) |
| | Tint_1712 | PFAM: histidine triad (HIT) protein; KEGG: swo:Swol_1000 hypothetical protein. (126 aa) |
| | Tint_1693 | KEGG: mpt:Mpe_A1615 cystathionine beta-lyase; TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (407 aa) |
| | Tint_1691 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); KEGG: rme:Rmet_1368 phosphoserine phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase. (293 aa) |
| | Tint_1667 | KEGG: tgr:Tgr7_2387 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II. (638 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (430 aa) |
| | ilvD-2 | TIGRFAM: dihydroxy-acid dehydratase; KEGG: aeh:Mlg_0418 dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (613 aa) |
| | Tint_1620 | KEGG: rpf:Rpic12D_2038 rhodanese domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein. (287 aa) |
| | dadA | FAD dependent oxidoreductase; Oxidative deamination of D-amino acids. (430 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1335 aa) |
| | ilvD | TIGRFAM: dihydroxy-acid dehydratase; KEGG: pol:Bpro_2052 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (561 aa) |
| | Tint_1419 | KEGG: vap:Vapar_1632 glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp. (471 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (400 aa) |
| | Tint_1386 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (165 aa) |
| | Tint_1345 | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (432 aa) |
| | Tint_1261 | Glycine oxidase ThiO; KEGG: pol:Bpro_0038 FAD dependent oxidoreductase; TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase. (365 aa) |
| | thrB | TIGRFAM: homoserine kinase; KEGG: aav:Aave_1928 homoserine kinase; PFAM: aminoglycoside phosphotransferase; Belongs to the pseudomonas-type ThrB family. (313 aa) |
| | Tint_1132 | TIGRFAM: tartrate dehydrogenase; KEGG: vei:Veis_2698 tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. (367 aa) |
| | argA | KEGG: vap:Vapar_2722 amino-acid N-acetyltransferase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: aspartate/glutamate/uridylate kinase; GCN5-related N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. (441 aa) |
| | selD | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (358 aa) |
| | Tint_1003 | TIGRFAM: phenylalanine-4-hydroxylase; KEGG: mpt:Mpe_A0347 phenylalanine 4-monooxygenase; PFAM: Aromatic amino acid hydroxylase-like. (288 aa) |
| | kynB | Arylformamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. (212 aa) |
| | kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (427 aa) |
| | kynA | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (286 aa) |
| | Tint_0994 | TIGRFAM: serine O-acetyltransferase; KEGG: mpt:Mpe_A2839 serine O-acetyltransferase. (255 aa) |
| | Tint_0933 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (311 aa) |
| | argD | TIGRFAM: acetylornithine and succinylornithine aminotransferase; KEGG: mpt:Mpe_A3029 acetylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (395 aa) |
| | Tint_0869 | PFAM: histidine triad (HIT) protein; KEGG: pna:Pnap_0705 histidine triad (HIT) protein. (116 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (367 aa) |
| | Tint_1987 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bac:BamMC406_4343 serine/threonine dehydratase. (331 aa) |
| | Tint_2006 | KEGG: spe:Spro_1379 GCN5-related N-acetyltransferase; manually curated; PFAM: GCN5-related N-acetyltransferase. (176 aa) |
| | Tint_2154 | KEGG: lch:Lcho_2893 acetolactate synthase 3 catalytic subunit; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding. (596 aa) |
| | Tint_2180 | Arginase; KEGG: mpt:Mpe_A1081 arginase; TIGRFAM: arginase; PFAM: Arginase/agmatinase/formiminoglutamase; Belongs to the arginase family. (306 aa) |
| | Tint_2218 | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; KEGG: dia:Dtpsy_0599 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (285 aa) |
| | argG | TIGRFAM: argininosuccinate synthase; KEGG: dia:Dtpsy_2233 argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (446 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (287 aa) |
| | Tint_2244 | PFAM: peptidase dimerisation domain protein; peptidase M20; KEGG: mpt:Mpe_A0775 hypothetical protein. (415 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (549 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa) |
| | metZ | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (404 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (500 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (292 aa) |
| | trpB-2 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (411 aa) |
| | trpF | KEGG: lch:Lcho_1681 phosphoribosylanthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. (220 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (378 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (359 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (215 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (467 aa) |
| | Tint_2426 | PFAM: glutamine amidotransferase class-II; KEGG: mgm:Mmc1_0879 glutamine amidotransferase, class-II. (270 aa) |
| | Tint_2455 | PFAM: FAD dependent oxidoreductase; KEGG: bja:bll4301 putative oxidoreductase protein. (347 aa) |
| | Tint_2467 | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (416 aa) |
| | Tint_2512 | KEGG: vap:Vapar_4079 isocitrate dehydrogenase (NAD(+)); PFAM: isocitrate/isopropylmalate dehydrogenase. (343 aa) |
| | gcvP | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (961 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (124 aa) |
| | Tint_2573 | KEGG: aav:Aave_3145 glycine cleavage system T protein; TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel. (386 aa) |
| | Tint_2655 | KEGG: syg:sync_0178 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II. (600 aa) |
| | Tint_2717 | PFAM: pyruvate carboxyltransferase; KEGG: cti:RALTA_A0129 hydroxymethylglutaryl-CoA lyase. (315 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (311 aa) |
| | Tint_2807 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (910 aa) |
| | Tint_2812 | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: lch:Lcho_4276 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (425 aa) |
| | Tint_2111 | TIGRFAM: threonine synthase; KEGG: mpt:Mpe_A1542 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (480 aa) |
| | Tint_2112 | KEGG: mpt:Mpe_A1541 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. (436 aa) |
| | Tint_2149 | PFAM: transferase hexapeptide repeat containing protein; KEGG: mma:MM_3269 serine O-acetyltransferase. (188 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa) |
| | Tint_2153 | KEGG: dac:Daci_4866 acetolactate synthase 3 regulatory subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein. (163 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (499 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (348 aa) |
| | trpC | KEGG: lch:Lcho_3876 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (290 aa) |
| | Tint_3027 | TIGRFAM: asparagine synthase family amidotransferase; asparagine synthase (glutamine-hydrolyzing); KEGG: rfr:Rfer_3652 asparagine synthase, glutamine-hydrolyzing; PFAM: asparagine synthase; glutamine amidotransferase class-II. (597 aa) |
| | Tint_2965 | SMART: Rhodanese domain protein; KEGG: pnu:Pnuc_0792 rhodanese domain-containing protein. (324 aa) |
| | metE | 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (793 aa) |
| | argH | KEGG: bur:Bcep18194_A5760 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase. (466 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (375 aa) |
| | Tint_0427 | Aspartate kinase; KEGG: bpr:GBP346_A2661 asparate kinase, monofunctional class; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (417 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (411 aa) |
| | Tint_0205 | KEGG: tro:trd_A0236 hypothetical protein. (303 aa) |
| | metXS | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (380 aa) |
| | Tint_0178 | Glutamate--putrescine ligase; KEGG: mpt:Mpe_A1901 L-glutamine synthetase; PFAM: glutamine synthetase catalytic region. (459 aa) |
| | Tint_0169 | Agmatinase; KEGG: mpt:Mpe_A1890 agmatinase; TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; Belongs to the arginase family. (317 aa) |
| | Tint_0163 | SMART: Rhodanese domain protein; KEGG: hna:Hneap_0198 rhodanese domain protein. (331 aa) |
| | Tint_0151 | Amidohydrolase; KEGG: bav:BAV1013 X-Pro dipeptidase; manually curated; PFAM: amidohydrolase; Twin-arginine translocation pathway, signal sequence, subgroup. (496 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (352 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa) |
| | dnaA | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (484 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (430 aa) |
| | Tint_2884 | PFAM: aminotransferase class IV; KEGG: bxe:Bxe_A4217 branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase. (291 aa) |
| | ilvA | Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (516 aa) |
| | Tint_2831 | KEGG: ajs:Ajs_1650 rhodanese domain-containing protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein. (347 aa) |
