STRINGSTRING
Tint_2812 Tint_2812 hisC hisC argD argD kynU kynU iscS iscS Tint_1483 Tint_1483 Tint_1693 Tint_1693 Tint_1737 Tint_1737 Tint_1752 Tint_1752 Tint_1849 Tint_1849 hisC-2 hisC-2 serC serC Tint_1874 Tint_1874 Tint_2095 Tint_2095 Tint_2113 Tint_2113 metZ metZ Tint_2431 Tint_2431 Tint_2467 Tint_2467 hemL hemL Tint_2570 Tint_2570 gcvP gcvP Tint_2583 Tint_2583 Tint_2732 Tint_2732 Tint_2788 Tint_2788 Tint_2790 Tint_2790 Tint_0168 Tint_0168 Tint_0176 Tint_0176 Tint_0179 Tint_0179 Tint_0187 Tint_0187 Tint_0267 Tint_0267 Tint_0494 Tint_0494 glyA glyA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tint_2812TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: lch:Lcho_4276 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (425 aa)
hisCKEGG: azo:azo3348 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (361 aa)
argDTIGRFAM: acetylornithine and succinylornithine aminotransferase; KEGG: mpt:Mpe_A3029 acetylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (395 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (427 aa)
iscSCysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (406 aa)
Tint_1483Lysine decarboxylase; KEGG: mms:mma_1191 arginine decarboxylase; PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein. (754 aa)
Tint_1693KEGG: mpt:Mpe_A1615 cystathionine beta-lyase; TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (407 aa)
Tint_1737Glutamine--scyllo-inositol transaminase; KEGG: bte:BTH_I2193 aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (378 aa)
Tint_1752KEGG: aav:Aave_2485 succinyldiaminopimelate transaminase; TIGRFAM: succinyldiaminopimelate transaminase; PFAM: aminotransferase class I and II. (403 aa)
Tint_1849PFAM: aminotransferase class I and II; KEGG: mpt:Mpe_A2293 aromatic amino acid aminotransferase. (401 aa)
hisC-2KEGG: rpf:Rpic12D_0846 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (376 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (367 aa)
Tint_1874PFAM: aminotransferase class-III; KEGG: bte:BTH_I1505 omega amino acid--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)
Tint_2095Manually curated; TIGRFAM: amino acid adenylation domain protein; KEGG: vap:Vapar_3184 amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; aminotransferase class-III. (2469 aa)
Tint_2113PFAM: aminotransferase class I and II; KEGG: mpt:Mpe_A1540 aminotransferase AlaT. (410 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (404 aa)
Tint_2431PFAM: aminotransferase class I and II; KEGG: mpt:Mpe_A2950 aminotransferase. (393 aa)
Tint_2467Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (416 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; KEGG: rme:Rmet_0667 glutamate-1-semialdehyde 2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III. (429 aa)
Tint_2570Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (356 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (961 aa)
Tint_2583PFAM: aminotransferase class I and II; KEGG: ajs:Ajs_1915 putative aminotransferase. (387 aa)
Tint_2732PFAM: aminotransferase class V; KEGG: rfr:Rfer_3691 aminotransferase, class V. (384 aa)
Tint_2788Transcriptional regulator, GntR family with aminotransferase domain; KEGG: dac:Daci_0595 transcriptional regulator; PFAM: aminotransferase class I and II; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH. (489 aa)
Tint_2790PFAM: aminotransferase class I and II; KEGG: lch:Lcho_3539 GntR family transcriptional regulator. (403 aa)
Tint_0168PFAM: aminotransferase class-III; KEGG: cvi:CV_2819 aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (454 aa)
Tint_0176KEGG: pna:Pnap_2866 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH. (505 aa)
Tint_0179PFAM: aminotransferase class-III; KEGG: lch:Lcho_1738 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (466 aa)
Tint_0187KEGG: mpt:Mpe_A1910 4-aminobutyrate aminotransferase; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (429 aa)
Tint_0267Transcriptional regulator, GntR family with aminotransferase domain; KEGG: lch:Lcho_4183 transcriptional regulator; PFAM: aminotransferase class I and II; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH. (477 aa)
Tint_0494PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; CBS domain containing protein; KEGG: sal:Sala_1573 DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (502 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
Your Current Organism:
Thiomonas intermedia
NCBI taxonomy Id: 75379
Other names: T. intermedia K12, Thiobacillus intermedius K12, Thiomonas intermedia K12, Thiomonas intermedia str. K12, Thiomonas intermedia strain K12
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