STRINGSTRING
Tint_2565 Tint_2565 Tint_2201 Tint_2201 dapF dapF tpiA tpiA rpiA rpiA Tint_2054 Tint_2054 Tint_2018 Tint_2018 gyrA gyrA Tint_1779 Tint_1779 gyrB gyrB surA surA Tint_0191 Tint_0191 queA queA Tint_0302 Tint_0302 Tint_0320 Tint_0320 Tint_0419 Tint_0419 Tint_0420 Tint_0420 parC parC parE parE gmhA gmhA Tint_0496 Tint_0496 Tint_0583 Tint_0583 Tint_0597 Tint_0597 Tint_0689 Tint_0689 Tint_0730 Tint_0730 gpmA gpmA Tint_0782 Tint_0782 Tint_0788 Tint_0788 purE purE truB truB glmM glmM tig tig Tint_1648 Tint_1648 Tint_1436 Tint_1436 hemL hemL Tint_2481 Tint_2481 Tint_2405 Tint_2405 hisA hisA Tint_0945 Tint_0945 Tint_1004 Tint_1004 hldD hldD pgi pgi Tint_1095 Tint_1095 Tint_1134 Tint_1134 nnrD nnrD Tint_1312 Tint_1312 Tint_1308 Tint_1308 Tint_2599 Tint_2599 Tint_2700 Tint_2700 fabA fabA Tint_2722 Tint_2722 Tint_2728 Tint_2728 Tint_2857 Tint_2857 Tint_2860 Tint_2860 Tint_3008 Tint_3008 Tint_3010 Tint_3010 Tint_3034 Tint_3034 Tint_3093 Tint_3093 Tint_3122 Tint_3122 murI murI Tint_2092 Tint_2092 dxr dxr ilvC ilvC truA truA trpF trpF icmF icmF Tint_2189 Tint_2189
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Tint_2565dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (187 aa)
Tint_2201DNA topoisomerase; KEGG: rbi:RB2501_04285 hypothetical protein; PFAM: Relaxase/mobilization nuclease family protein. (718 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (287 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (220 aa)
Tint_2054PFAM: 4-oxalocrotonate tautomerase; KEGG: bxe:Bxe_C0717 hypothetical protein. (139 aa)
Tint_2018TIGRFAM: DNA topoisomerase III; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; KEGG: afe:Lferr_0283 DNA topoisomerase III; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein. (723 aa)
gyrADNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (868 aa)
Tint_1779RNA-binding S4 domain protein; KEGG: vap:Vapar_2182 pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; SMART: RNA-binding S4 domain protein; Belongs to the pseudouridine synthase RsuA family. (562 aa)
gyrBDNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (827 aa)
surASurA domain protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (459 aa)
Tint_0191KpsF/GutQ family protein; SMART: CBS domain containing protein; TIGRFAM: KpsF/GutQ family protein; KEGG: rso:RSc0413 hypothetical protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; Belongs to the SIS family. GutQ/KpsF subfamily. (332 aa)
queAS-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (406 aa)
Tint_0302PFAM: Enoyl-CoA hydratase/isomerase; KEGG: bvi:Bcep1808_0521 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa)
Tint_0320PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: min:Minf_2079 parvulin-like peptidyl-prolyl isomerase. (282 aa)
Tint_0419Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (163 aa)
Tint_0420Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (214 aa)
parCDNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (777 aa)
parEDNA topoisomerase (ATP-hydrolyzing); Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (652 aa)
gmhASugar isomerase (SIS); Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (199 aa)
Tint_0496KEGG: lpf:lpl0790 N-acylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (463 aa)
Tint_0583TIGRFAM: DNA topoisomerase III; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; KEGG: mpt:Mpe_A0265 DNA topoisomerase III; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein. (843 aa)
Tint_0597Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (367 aa)
Tint_0689PFAM: Enoyl-CoA hydratase/isomerase; KEGG: aav:Aave_3074 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (220 aa)
Tint_0730PFAM: Aldose 1-epimerase; KEGG: tbd:Tbd_2730 dihydroxyacid dehydratase; Belongs to the glucose-6-phosphate 1-epimerase family. (300 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (235 aa)
Tint_0782KEGG: mpt:Mpe_A2569 putative FkbP-type peptidyl-prolyl cis-trans isomerase. (168 aa)
Tint_0788KEGG: aha:AHA_4103 UDP-glucose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (340 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (162 aa)
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (345 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (438 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (444 aa)
Tint_1648KEGG: pol:Bpro_0950 peptidylprolyl isomerase, FKBP-type. (175 aa)
Tint_1436PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: mms:mma_1544 PpiC-type peptidyl-prolyl cis-trans isomerase. (262 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; KEGG: rme:Rmet_0667 glutamate-1-semialdehyde 2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III. (429 aa)
Tint_2481PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: bpl:BURPS1106A_A1541 peptidyl-prolyl cis-trans isomerase domain-containing protein. (226 aa)
Tint_2405Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (329 aa)
hisATIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; KEGG: reh:H16_A3411 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; PFAM: histidine biosynthesis protein. (244 aa)
Tint_0945Phosphoglucomutase; KEGG: rme:Rmet_2716 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase. (458 aa)
Tint_1004KEGG: tmz:Tmz1t_0854 maleylacetoacetate isomerase; TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase domain. (214 aa)
hldDADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (330 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: bpt:Bpet4022 hypothetical protein; Belongs to the GPI family. (502 aa)
Tint_1095PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; KEGG: similar to phosphoglucomutase 1. (543 aa)
Tint_1134PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: rpf:Rpic12D_1532 PpiC-type peptidyl-prolyl cis-trans isomerase. (640 aa)
nnrDCarbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (525 aa)
Tint_1312Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (342 aa)
Tint_1308PFAM: Enoyl-CoA hydratase/isomerase; KEGG: cti:RALTA_A0791 enoyl-CoA hydratase. (268 aa)
Tint_2599PFAM: Enoyl-CoA hydratase/isomerase; KEGG: bmj:BMULJ_02680 enoyl-CoA hydratase. (258 aa)
Tint_2700Disulfide bond isomerase, DsbC/G-like protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (245 aa)
fabABeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (171 aa)
Tint_2722PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rso:RSc0267 enoyl-CoA hydratase. (266 aa)
Tint_2728PFAM: DSBA oxidoreductase; KEGG: app:CAP2UW1_4329 DsbA oxidoreductase. (201 aa)
Tint_2857TIGRFAM: hydroxypyruvate isomerase; KEGG: pol:Bpro_4562 hydroxypyruvate isomerase; PFAM: Xylose isomerase domain protein TIM barrel; Belongs to the hyi family. (257 aa)
Tint_2860KEGG: bmj:BMULJ_04492 4-oxalocrotonate tautomerase; TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; PFAM: 4-oxalocrotonate tautomerase. (63 aa)
Tint_3008PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mpt:Mpe_A0984 short chain enoyl-CoA hydratase / enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (265 aa)
Tint_3010PFAM: Enoyl-CoA hydratase/isomerase; KEGG: pol:Bpro_1631 enoyl-CoA hydratase/isomerase. (274 aa)
Tint_3034KEGG: app:CAP2UW1_2750 thiol-disulfide isomerase and thioredoxins family protein. (78 aa)
Tint_3093KEGG: reh:PHG074 putative sedoheptulose 7-phosphate isomerase. (231 aa)
Tint_3122TIGRFAM: ribulose-phosphate 3-epimerase; KEGG: bgl:bglu_1g04420 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (235 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (263 aa)
Tint_2092TIGRFAM: secretion ATPase, PEP-CTERM locus subfamily; PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: lch:Lcho_3505 secretion ATPase; SMART: AAA ATPase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (715 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (401 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (257 aa)
trpFKEGG: lch:Lcho_1681 phosphoribosylanthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. (220 aa)
icmFmethylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1093 aa)
Tint_2189PFAM: pseudouridine synthase; RNA-binding S4 domain protein; KEGG: pol:Bpro_0606 ribosomal large subunit pseudouridine synthase F. (300 aa)
Your Current Organism:
Thiomonas intermedia
NCBI taxonomy Id: 75379
Other names: T. intermedia K12, Thiobacillus intermedius K12, Thiomonas intermedia K12, Thiomonas intermedia str. K12, Thiomonas intermedia strain K12
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