STRINGSTRING
glk glk Tint_0103 Tint_0103 Tint_0104 Tint_0104 Tint_0496 Tint_0496 glmS glmS glmU glmU Tint_0788 Tint_0788 Tint_0826 Tint_0826 murA murA Tint_0945 Tint_0945 pgi pgi glgC glgC Tint_1095 Tint_1095 Tint_1149 Tint_1149 Tint_1300 Tint_1300 Tint_1301 Tint_1301 murB murB Tint_1496 Tint_1496 Tint_1516 Tint_1516 glmM glmM Tint_1737 Tint_1737 Tint_1738 Tint_1738 Tint_1740 Tint_1740 Tint_1801 Tint_1801 Tint_1803 Tint_1803 nagZ nagZ Tint_2408 Tint_2408 Tint_2652 Tint_2652 Tint_2653 Tint_2653
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glkTIGRFAM: glucokinase; KEGG: cvi:CV_0147 glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. (326 aa)
Tint_0103PFAM: aminoglycoside phosphotransferase; KEGG: mms:mma_0416 hypothetical protein. (342 aa)
Tint_0104PFAM: Nucleotidyl transferase; KEGG: rpf:Rpic12D_0402 nucleotidyl transferase. (228 aa)
Tint_0496KEGG: lpf:lpl0790 N-acylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (463 aa)
glmSGlucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (611 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (466 aa)
Tint_0788KEGG: aha:AHA_4103 UDP-glucose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (340 aa)
Tint_0826PFAM: PTS system fructose subfamily IIA component; KEGG: rso:RSc0346 hypothetical protein. (153 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (430 aa)
Tint_0945Phosphoglucomutase; KEGG: rme:Rmet_2716 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase. (458 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: bpt:Bpet4022 hypothetical protein; Belongs to the GPI family. (502 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (442 aa)
Tint_1095PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; KEGG: similar to phosphoglucomutase 1. (543 aa)
Tint_1149TIGRFAM: nucleotide sugar dehydrogenase; KEGG: net:Neut_1093 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (441 aa)
Tint_1300KEGG: lch:Lcho_3069 nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (426 aa)
Tint_1301PFAM: NAD-dependent epimerase/dehydratase; KEGG: lch:Lcho_3068 NAD-dependent epimerase/dehydratase. (337 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (341 aa)
Tint_1496PFAM: ROK family protein; KEGG: tmz:Tmz1t_4078 ROK family protein. (336 aa)
Tint_1516KEGG: rso:RSc0897 hydrolase protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase. (222 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (438 aa)
Tint_1737Glutamine--scyllo-inositol transaminase; KEGG: bte:BTH_I2193 aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (378 aa)
Tint_1738PFAM: glycosyl transferase family 2; KEGG: bpr:GBP346_A2346 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase. (340 aa)
Tint_1740PFAM: NAD-dependent epimerase/dehydratase; KEGG: bpy:Bphyt_1798 NAD-dependent epimerase/dehydratase family protein. (351 aa)
Tint_1801PFAM: polysaccharide deacetylase; KEGG: cvi:CV_0745 hypothetical protein. (299 aa)
Tint_1803KEGG: bgl:bglu_1g21910 UTP--glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase. (295 aa)
nagZGlycoside hydrolase family 3 domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (361 aa)
Tint_2408PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; ferredoxin; KEGG: pna:Pnap_3204 CDP-6-deoxy-delta-3,4-glucoseen reductase. (343 aa)
Tint_2652KEGG: mta:Moth_0756 N-acetylneuraminate synthase; PFAM: N-acetylneuraminic acid synthase domain; SAF domain protein. (375 aa)
Tint_2653KEGG: sal:Sala_1578 acylneuraminate cytidylyltransferase; PFAM: acylneuraminate cytidylyltransferase. (234 aa)
Your Current Organism:
Thiomonas intermedia
NCBI taxonomy Id: 75379
Other names: T. intermedia K12, Thiobacillus intermedius K12, Thiomonas intermedia K12, Thiomonas intermedia str. K12, Thiomonas intermedia strain K12
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