STRINGSTRING
Tint_0004 Tint_0004 Tint_0005 Tint_0005 Tint_0142 Tint_0142 Tint_0224 Tint_0224 Tint_0437 Tint_0437 Tint_0447 Tint_0447 eno eno glyA glyA gpmA gpmA Tint_0878 Tint_0878 Tint_0943 Tint_0943 ackA ackA Tint_1147 Tint_1147 Tint_1596 Tint_1596 Tint_1691 Tint_1691 eno-2 eno-2 fbp-2 fbp-2 ppc ppc serC serC acsA acsA Tint_2122 Tint_2122 eno-3 eno-3 mdh mdh Tint_2855 Tint_2855 Tint_2957 Tint_2957 Tint_2959 Tint_2959 Tint_2960 Tint_2960 Tint_3193 Tint_3193
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Tint_0004PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; KEGG: vap:Vapar_4073 respiratory-chain NADH dehydrogenase domain 51 kDa subunit. (626 aa)
Tint_0005KEGG: vap:Vapar_4072 formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (977 aa)
Tint_0142Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
Tint_0224PFAM: Phosphoglycerate mutase; KEGG: pol:Bpro_4091 phosphoglycerate mutase. (216 aa)
Tint_0437Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (809 aa)
Tint_0447PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: mba:Mbar_A0176 aldolase. (304 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (235 aa)
Tint_0878TIGRFAM: 1-phosphofructokinase; KEGG: afr:AFE_1807 carbohydrate kinase, PfkB family; PFAM: PfkB domain protein. (317 aa)
Tint_0943PFAM: AMP-dependent synthetase and ligase; KEGG: app:CAP2UW1_2247 AMP-dependent synthetase and ligase. (573 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
Tint_1147Phosphate acetyltransferase; KEGG: rpd:RPD_1127 bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase. (480 aa)
Tint_1596KEGG: gyc:GYMC61_1806 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulfolactate phosphatase; Belongs to the ComB family. (242 aa)
Tint_1691TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); KEGG: rme:Rmet_1368 phosphoserine phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase. (293 aa)
eno-2Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
fbp-2PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: dia:Dtpsy_2250 inositol phosphatase/fructose-16-bisphosphatase. (336 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (944 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (367 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (659 aa)
Tint_2122Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (795 aa)
eno-3Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa)
Tint_2855KEGG: ajs:Ajs_1122 hydroxypyruvate reductase; PFAM: MOFRL domain protein. (435 aa)
Tint_2957TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: bpe:BP1475 formate dehydrogenase subunit C precursor. (394 aa)
Tint_2959PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: vap:Vapar_4061 4Fe-4S ferredoxin iron-sulfur binding domain protein. (210 aa)
Tint_2960Nitrate reductase; KEGG: mpt:Mpe_A1170 formate dehydrogenase large subunit precursor; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (995 aa)
Tint_3193PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: dia:Dtpsy_1729 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding. (336 aa)
Your Current Organism:
Thiomonas intermedia
NCBI taxonomy Id: 75379
Other names: T. intermedia K12, Thiobacillus intermedius K12, Thiomonas intermedia K12, Thiomonas intermedia str. K12, Thiomonas intermedia strain K12
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