STRINGSTRING
glyA glyA AGB42552.1 AGB42552.1 AGB42617.1 AGB42617.1 AGB42826.1 AGB42826.1 AGB43229.1 AGB43229.1 AGB43248.1 AGB43248.1 AGB43428.1 AGB43428.1 argD argD metZ metZ AGB48198.1 AGB48198.1 AGB48112.1 AGB48112.1 AGB48079.1 AGB48079.1 AGB48055.1 AGB48055.1 AGB48013.1 AGB48013.1 glyA-3 glyA-3 AGB47935.1 AGB47935.1 AGB47933.1 AGB47933.1 AGB47711.1 AGB47711.1 AGB47708.1 AGB47708.1 phnW phnW AGB47692.1 AGB47692.1 AGB47657.1 AGB47657.1 AGB47324.1 AGB47324.1 AGB47219.1 AGB47219.1 AGB47039.1 AGB47039.1 kbl kbl glyA-2 glyA-2 AGB46818.1 AGB46818.1 AGB46785.1 AGB46785.1 AGB46780.1 AGB46780.1 AGB46754.1 AGB46754.1 AGB46722.1 AGB46722.1 AGB46718.1 AGB46718.1 AGB46503.1 AGB46503.1 kynU kynU AGB46318.1 AGB46318.1 AGB46210.1 AGB46210.1 gcvP gcvP AGB46153.1 AGB46153.1 AGB46075.1 AGB46075.1 AGB46031.1 AGB46031.1 AGB45987.1 AGB45987.1 AGB45971.1 AGB45971.1 AGB45959.1 AGB45959.1 AGB45946.1 AGB45946.1 AGB45777.1 AGB45777.1 AGB45732.1 AGB45732.1 AGB45592.1 AGB45592.1 AGB45455.1 AGB45455.1 AGB44954.1 AGB44954.1 AGB44911.1 AGB44911.1 AGB44723.1 AGB44723.1 AGB44537.1 AGB44537.1 AGB44414.1 AGB44414.1 AGB44381.1 AGB44381.1 hisC hisC AGB43961.1 AGB43961.1 AGB43812.1 AGB43812.1 AGB43604.1 AGB43604.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glyAGlycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (430 aa)
AGB42552.1TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (425 aa)
AGB42617.1TIGRFAM: cysteine desulfurase family protein, VC1184 subfamily. (420 aa)
AGB42826.1PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa)
AGB43229.1PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. (495 aa)
AGB43248.1Cystathionine beta-lyase/cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. (389 aa)
AGB43428.1Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. (400 aa)
argDPFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine transaminases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (399 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (396 aa)
AGB48198.17-keto-8-aminopelargonate synthetase-like enzyme; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; 5-aminolevulinic acid synthase. (425 aa)
AGB48112.1Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. (405 aa)
AGB48079.1Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (418 aa)
AGB48055.1PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (430 aa)
AGB48013.1PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (468 aa)
glyA-3Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (445 aa)
AGB47935.1PFAM: Aminotransferase class-III; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (421 aa)
AGB47933.17-keto-8-aminopelargonate synthetase-like enzyme; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase. (379 aa)
AGB47711.1PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa)
AGB47708.1Transcriptional regulator with HTH domain and aminotransferase domain; PFAM: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II. (461 aa)
phnW2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily. (399 aa)
AGB47692.14-aminobutyrate aminotransferase family protein; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)
AGB47657.14-aminobutyrate aminotransferase family protein; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (433 aa)
AGB47324.1Putative PLP-dependent enzyme possibly involved in cell wall biogenesis; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family. (380 aa)
AGB47219.1PLP-dependent enzyme, histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase. (370 aa)
AGB47039.1Cystathionine beta-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: cystathionine beta-lyase, bacterial. (395 aa)
kbl2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (395 aa)
glyA-2Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (437 aa)
AGB46818.1OAH/OAS sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase. (426 aa)
AGB46785.1Cysteine desulfurase family protein; PFAM: Aminotransferase class-V. (386 aa)
AGB46780.1Cysteine desulfurase-like protein, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (414 aa)
AGB46754.1Transcriptional regulator with HTH domain and aminotransferase domain; PFAM: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II. (469 aa)
AGB46722.1PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein, VC1184 subfamily. (422 aa)
AGB46718.1PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (461 aa)
AGB46503.1PFAM: Aminotransferase class I and II. (395 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (416 aa)
AGB46318.1PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. (470 aa)
AGB46210.1Cystathionine beta-lyase/cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. (395 aa)
gcvPGlycine dehydrogenase, decarboxylating; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (936 aa)
AGB46153.1PFAM: Aminotransferase class I and II. (405 aa)
AGB46075.1Transcriptional regulator with HTH domain and aminotransferase domain; PFAM: Aminotransferase class I and II; Bacterial regulatory proteins, gntR family. (466 aa)
AGB46031.1PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa)
AGB45987.1PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (490 aa)
AGB45971.1PFAM: Aminotransferase class I and II. (393 aa)
AGB45959.1PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; manually curated. (341 aa)
AGB45946.1Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. (396 aa)
AGB45777.1Cystathionine beta-lyase/cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. (371 aa)
AGB45732.1PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (442 aa)
AGB45592.1Transcriptional regulator with HTH domain and aminotransferase domain; PFAM: Aminotransferase class I and II. (402 aa)
AGB45455.1PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (442 aa)
AGB44954.1Putative PLP-dependent enzyme possibly involved in cell wall biogenesis; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family. (378 aa)
AGB44911.15-aminolevulinic acid synthase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; 5-aminolevulinic acid synthase. (425 aa)
AGB44723.1PFAM: Aminotransferase class I and II. (400 aa)
AGB44537.1Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. (392 aa)
AGB44414.1PFAM: Aminotransferase class I and II. (394 aa)
AGB44381.1Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (350 aa)
hisCPFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (369 aa)
AGB43961.1PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (471 aa)
AGB43812.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (391 aa)
AGB43604.1PFAM: Aminotransferase class I and II. (366 aa)
Your Current Organism:
Mesorhizobium australicum
NCBI taxonomy Id: 754035
Other names: M. australicum WSM2073, Mesorhizobium australicum LMG 24608, Mesorhizobium australicum WSM2073, Mesorhizobium australicum str. WSM2073, Mesorhizobium australicum strain WSM2073, Mesorhizobium sp. WSM 2073, Mesorhizobium sp. WSM2073
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