STRINGSTRING
AGB42633.1 AGB42633.1 ilvD ilvD AGB42783.1 AGB42783.1 argB argB AGB43454.1 AGB43454.1 asd asd leuB leuB leuD leuD leuC leuC AGB43839.1 AGB43839.1 AGB44041.1 AGB44041.1 argJ argJ AGB44141.1 AGB44141.1 AGB44414.1 AGB44414.1 leuA leuA ilvE ilvE AGB44723.1 AGB44723.1 AGB44833.1 AGB44833.1 AGB45021.1 AGB45021.1 AGB45744.1 AGB45744.1 AGB45869.1 AGB45869.1 AGB45870.1 AGB45870.1 ilvC ilvC ilvD-2 ilvD-2 AGB46382.1 AGB46382.1 AGB46503.1 AGB46503.1 AGB46770.1 AGB46770.1 argC argC AGB47168.1 AGB47168.1 AGB47281.1 AGB47281.1 AGB47659.1 AGB47659.1 AGB47668.1 AGB47668.1 AGB48079.1 AGB48079.1 argD argD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
AGB42633.1Dihydroxyacid dehydratase/phosphogluconate dehydratase; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (601 aa)
ilvDPFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (614 aa)
AGB42783.1Thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Belongs to the TPP enzyme family. (526 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (308 aa)
AGB43454.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (896 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (367 aa)
leuD3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (469 aa)
AGB43839.1PFAM: Citrate synthase. (380 aa)
AGB44041.1Thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. (517 aa)
argJGlutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (413 aa)
AGB44141.1PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. (417 aa)
AGB44414.1PFAM: Aminotransferase class I and II. (394 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (579 aa)
ilvEBranched-chain amino acid aminotransferase, group I; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (297 aa)
AGB44723.1PFAM: Aminotransferase class I and II. (400 aa)
AGB44833.1PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. (450 aa)
AGB45021.1Acetylornithine deacetylase ArgE; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase (ArgE). (398 aa)
AGB45744.1Thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Belongs to the TPP enzyme family. (549 aa)
AGB45869.1Acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type. (598 aa)
AGB45870.1PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit. (191 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
ilvD-2PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (574 aa)
AGB46382.1PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. (440 aa)
AGB46503.1PFAM: Aminotransferase class I and II. (395 aa)
AGB46770.1Isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, eukaryotic type; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (403 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase, uncommon form; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (308 aa)
AGB47168.1PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (540 aa)
AGB47281.1Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; PFAM: Aminotransferase class IV. (292 aa)
AGB47659.1PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. (433 aa)
AGB47668.1Thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Belongs to the TPP enzyme family. (548 aa)
AGB48079.1Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (418 aa)
argDPFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine transaminases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (399 aa)
Your Current Organism:
Mesorhizobium australicum
NCBI taxonomy Id: 754035
Other names: M. australicum WSM2073, Mesorhizobium australicum LMG 24608, Mesorhizobium australicum WSM2073, Mesorhizobium australicum str. WSM2073, Mesorhizobium australicum strain WSM2073, Mesorhizobium sp. WSM 2073, Mesorhizobium sp. WSM2073
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