node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBL55700.1 | CBL56239.1 | PFREUD_01850 | PFREUD_07080 | (S)-Dihydroorotate + Oxygen <=> Orotate + H2O2. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.916 |
CBL55700.1 | carA | PFREUD_01850 | PFREUD_11480 | (S)-Dihydroorotate + Oxygen <=> Orotate + H2O2. | Carbamoyl-phosphate synthase small chain; The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides; Belongs to the CarA family. | 0.741 |
CBL55700.1 | pyrB | PFREUD_01850 | PFREUD_17440 | (S)-Dihydroorotate + Oxygen <=> Orotate + H2O2. | Carbamoyl phosphate + L-Aspartate <=> Orthophosphate + N-Carbamoyl-L-aspartate; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.791 |
CBL55700.1 | pyrD | PFREUD_01850 | PFREUD_11460 | (S)-Dihydroorotate + Oxygen <=> Orotate + H2O2. | Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.900 |
CBL55700.1 | pyrF | PFREUD_01850 | PFREUD_11450 | (S)-Dihydroorotate + Oxygen <=> Orotate + H2O2. | Orotidine 5-phosphate decarboxylase (OMP decarboxylase) (OMPDCase) (OMPdecase); Orotidine 5 prime-phosphate <=> UMP + CO2. | 0.791 |
CBL56239.1 | CBL55700.1 | PFREUD_07080 | PFREUD_01850 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | (S)-Dihydroorotate + Oxygen <=> Orotate + H2O2. | 0.916 |
CBL56239.1 | carA | PFREUD_07080 | PFREUD_11480 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Carbamoyl-phosphate synthase small chain; The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides; Belongs to the CarA family. | 0.741 |
CBL56239.1 | pyrB | PFREUD_07080 | PFREUD_17440 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Carbamoyl phosphate + L-Aspartate <=> Orthophosphate + N-Carbamoyl-L-aspartate; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.791 |
CBL56239.1 | pyrD | PFREUD_07080 | PFREUD_11460 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.900 |
CBL56239.1 | pyrF | PFREUD_07080 | PFREUD_11450 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Orotidine 5-phosphate decarboxylase (OMP decarboxylase) (OMPDCase) (OMPdecase); Orotidine 5 prime-phosphate <=> UMP + CO2. | 0.791 |
apt | purD | PFREUD_11660 | PFREUD_04000 | Adenine phosphoribosyltransferase (AMP:diphosphate phospho-D-ribosyltransferase); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylamine-glycine ligase; ATP + 5-Phosphoribosylamine + Glycine <=> ADP + Orthophosphate + 5prime-Phosphoribosylglycinamide; Belongs to the GARS family. | 0.415 |
apt | purF | PFREUD_11660 | PFREUD_04770 | Adenine phosphoribosyltransferase (AMP:diphosphate phospho-D-ribosyltransferase); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.444 |
apt | upp | PFREUD_11660 | PFREUD_19730 | Adenine phosphoribosyltransferase (AMP:diphosphate phospho-D-ribosyltransferase); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Uracil phosphoribosyltransferase (UMP pyrophosphorylase) (UPRTase); Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.488 |
carA | CBL55700.1 | PFREUD_11480 | PFREUD_01850 | Carbamoyl-phosphate synthase small chain; The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides; Belongs to the CarA family. | (S)-Dihydroorotate + Oxygen <=> Orotate + H2O2. | 0.741 |
carA | CBL56239.1 | PFREUD_11480 | PFREUD_07080 | Carbamoyl-phosphate synthase small chain; The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.741 |
carA | purD | PFREUD_11480 | PFREUD_04000 | Carbamoyl-phosphate synthase small chain; The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides; Belongs to the CarA family. | Phosphoribosylamine-glycine ligase; ATP + 5-Phosphoribosylamine + Glycine <=> ADP + Orthophosphate + 5prime-Phosphoribosylglycinamide; Belongs to the GARS family. | 0.694 |
carA | purF | PFREUD_11480 | PFREUD_04770 | Carbamoyl-phosphate synthase small chain; The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides; Belongs to the CarA family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.962 |
carA | pyrB | PFREUD_11480 | PFREUD_17440 | Carbamoyl-phosphate synthase small chain; The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides; Belongs to the CarA family. | Carbamoyl phosphate + L-Aspartate <=> Orthophosphate + N-Carbamoyl-L-aspartate; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.999 |
carA | pyrD | PFREUD_11480 | PFREUD_11460 | Carbamoyl-phosphate synthase small chain; The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides; Belongs to the CarA family. | Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.944 |
carA | pyrF | PFREUD_11480 | PFREUD_11450 | Carbamoyl-phosphate synthase small chain; The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides; Belongs to the CarA family. | Orotidine 5-phosphate decarboxylase (OMP decarboxylase) (OMPDCase) (OMPdecase); Orotidine 5 prime-phosphate <=> UMP + CO2. | 0.976 |