STRINGSTRING
pyrD pyrD WPG_0367 WPG_0367 pyrE pyrE carA carA purK purK purE purE WPG_0823 WPG_0823 WPG_1115 WPG_1115 WPG_1212 WPG_1212 WPG_1215 WPG_1215 purD purD WPG_1674 WPG_1674 purH purH purL purL WPG_2596 WPG_2596 WPG_2614 WPG_2614 purC purC pyrB pyrB WPG_2997 WPG_2997 WPG_3229 WPG_3229
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (346 aa)
WPG_0367Phosphoribosylformylglycinamidine cyclo-ligase. (392 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (214 aa)
carACarbamoyl-phosphate synthase small chain; Belongs to the CarA family. (367 aa)
purKPhosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (384 aa)
purEPhosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (152 aa)
WPG_0823ATP-grasp enzyme-like protein. (316 aa)
WPG_1115Hypothetical protein. (170 aa)
WPG_1212Phosphoribosylglycinamide formyltransferase. (188 aa)
WPG_1215Amidophosphoribosyltransferase. (632 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (423 aa)
WPG_1674Dihydroorotase. (448 aa)
purHIMP cyclohydrolase. (522 aa)
purLPhosphoribosylformylglycinamidine synthase, synthetase subunit; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1218 aa)
WPG_2596Carbamoyl-phosphate synthase large chain. (951 aa)
WPG_2614Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (447 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (316 aa)
pyrBAspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (309 aa)
WPG_2997Dihydroorotase. (417 aa)
WPG_3229ATP-grasp enzyme-like protein. (323 aa)
Your Current Organism:
Winogradskyella sp. PG2
NCBI taxonomy Id: 754409
Other names: W. sp. PG-2, Winogradskyella sp. PG-2
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