(9 nodes) Nicotinate and nicotinamide metabolism network (Winogradskyella sp. PG2)

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Your Input:
	WPG_0698	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (262 aa)
	nadK	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (292 aa)
	nadD	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (192 aa)
	WPG_1829	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (270 aa)
	surE	5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (257 aa)
	WPG_2521	Molybdopterin binding motif, CinA N-terminal domain / C-terminal domain of CinA type S; Belongs to the CinA family. (415 aa)
	cobB	NAD-dependent protein deacetylase of SIR2 family; Belongs to the sirtuin family. Class III subfamily. (225 aa)
	WPG_2638	Quinolinate phosphoribosyltransferase; Belongs to the NadC/ModD family. (285 aa)
	WPG_3514	5'-nucleotidase; Belongs to the 5'-nucleotidase family. (308 aa)

Your Current Organism:

Winogradskyella sp. PG2

NCBI taxonomy Id: 754409
Other names: W. sp. PG-2, Winogradskyella sp. PG-2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
WPG_0698	WPG_2521	WPG_0698	WPG_2521	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	Molybdopterin binding motif, CinA N-terminal domain / C-terminal domain of CinA type S; Belongs to the CinA family.	0.523
WPG_0698	cobB	WPG_0698	WPG_2622	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	NAD-dependent protein deacetylase of SIR2 family; Belongs to the sirtuin family. Class III subfamily.	0.919
WPG_0698	nadD	WPG_0698	WPG_1528	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.938
WPG_0698	nadK	WPG_0698	WPG_0854	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.924
WPG_1829	WPG_3514	WPG_1829	WPG_3514	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	5'-nucleotidase; Belongs to the 5'-nucleotidase family.	0.911
WPG_1829	cobB	WPG_1829	WPG_2622	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	NAD-dependent protein deacetylase of SIR2 family; Belongs to the sirtuin family. Class III subfamily.	0.910
WPG_1829	surE	WPG_1829	WPG_1923	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.901
WPG_2521	WPG_0698	WPG_2521	WPG_0698	Molybdopterin binding motif, CinA N-terminal domain / C-terminal domain of CinA type S; Belongs to the CinA family.	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	0.523
WPG_2521	WPG_2638	WPG_2521	WPG_2638	Molybdopterin binding motif, CinA N-terminal domain / C-terminal domain of CinA type S; Belongs to the CinA family.	Quinolinate phosphoribosyltransferase; Belongs to the NadC/ModD family.	0.936
WPG_2521	WPG_3514	WPG_2521	WPG_3514	Molybdopterin binding motif, CinA N-terminal domain / C-terminal domain of CinA type S; Belongs to the CinA family.	5'-nucleotidase; Belongs to the 5'-nucleotidase family.	0.913
WPG_2521	nadD	WPG_2521	WPG_1528	Molybdopterin binding motif, CinA N-terminal domain / C-terminal domain of CinA type S; Belongs to the CinA family.	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.950
WPG_2521	nadK	WPG_2521	WPG_0854	Molybdopterin binding motif, CinA N-terminal domain / C-terminal domain of CinA type S; Belongs to the CinA family.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.405
WPG_2521	surE	WPG_2521	WPG_1923	Molybdopterin binding motif, CinA N-terminal domain / C-terminal domain of CinA type S; Belongs to the CinA family.	5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.913
WPG_2638	WPG_2521	WPG_2638	WPG_2521	Quinolinate phosphoribosyltransferase; Belongs to the NadC/ModD family.	Molybdopterin binding motif, CinA N-terminal domain / C-terminal domain of CinA type S; Belongs to the CinA family.	0.936
WPG_2638	WPG_3514	WPG_2638	WPG_3514	Quinolinate phosphoribosyltransferase; Belongs to the NadC/ModD family.	5'-nucleotidase; Belongs to the 5'-nucleotidase family.	0.900
WPG_2638	nadD	WPG_2638	WPG_1528	Quinolinate phosphoribosyltransferase; Belongs to the NadC/ModD family.	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.923
WPG_2638	surE	WPG_2638	WPG_1923	Quinolinate phosphoribosyltransferase; Belongs to the NadC/ModD family.	5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.904
WPG_3514	WPG_1829	WPG_3514	WPG_1829	5'-nucleotidase; Belongs to the 5'-nucleotidase family.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.911
WPG_3514	WPG_2521	WPG_3514	WPG_2521	5'-nucleotidase; Belongs to the 5'-nucleotidase family.	Molybdopterin binding motif, CinA N-terminal domain / C-terminal domain of CinA type S; Belongs to the CinA family.	0.913
WPG_3514	WPG_2638	WPG_3514	WPG_2638	5'-nucleotidase; Belongs to the 5'-nucleotidase family.	Quinolinate phosphoribosyltransferase; Belongs to the NadC/ModD family.	0.900