(5 nodes) Mixed, incl. GspF/PilC family, and Type II secretion system protein GspE, N-terminal network (Methylophaga frappieri)

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Your Input:
	zapD	Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. (258 aa)
	coaE	Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (203 aa)
	Q7C_2226	Leader peptidase (Prepilin peptidase) / N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (289 aa)
	Q7C_2227	Type IV fimbrial assembly protein PilC; PFAM: Bacterial type II secretion system protein F domain. (413 aa)
	Q7C_2228	Type IV fimbrial assembly, ATPase PilB; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: type IV-A pilus assembly ATPase PilB. (572 aa)

Your Current Organism:

Methylophaga frappieri

NCBI taxonomy Id: 754477
Other names: ATCC BAA-2434, DSM 25690, M. frappieri, Methylophaga frappieri Villeneuve et al. 2013, Methylophaga sp. JAM7, strain JAM7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Q7C_2226	Q7C_2227	Q7C_2226	Q7C_2227	Leader peptidase (Prepilin peptidase) / N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	Type IV fimbrial assembly protein PilC; PFAM: Bacterial type II secretion system protein F domain.	0.980
Q7C_2226	Q7C_2228	Q7C_2226	Q7C_2228	Leader peptidase (Prepilin peptidase) / N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	Type IV fimbrial assembly, ATPase PilB; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: type IV-A pilus assembly ATPase PilB.	0.970
Q7C_2226	coaE	Q7C_2226	Q7C_2225	Leader peptidase (Prepilin peptidase) / N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	0.880
Q7C_2226	zapD	Q7C_2226	Q7C_2224	Leader peptidase (Prepilin peptidase) / N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.	0.832
Q7C_2227	Q7C_2226	Q7C_2227	Q7C_2226	Type IV fimbrial assembly protein PilC; PFAM: Bacterial type II secretion system protein F domain.	Leader peptidase (Prepilin peptidase) / N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	0.980
Q7C_2227	Q7C_2228	Q7C_2227	Q7C_2228	Type IV fimbrial assembly protein PilC; PFAM: Bacterial type II secretion system protein F domain.	Type IV fimbrial assembly, ATPase PilB; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: type IV-A pilus assembly ATPase PilB.	0.987
Q7C_2227	coaE	Q7C_2227	Q7C_2225	Type IV fimbrial assembly protein PilC; PFAM: Bacterial type II secretion system protein F domain.	Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	0.811
Q7C_2227	zapD	Q7C_2227	Q7C_2224	Type IV fimbrial assembly protein PilC; PFAM: Bacterial type II secretion system protein F domain.	Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.	0.800
Q7C_2228	Q7C_2226	Q7C_2228	Q7C_2226	Type IV fimbrial assembly, ATPase PilB; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: type IV-A pilus assembly ATPase PilB.	Leader peptidase (Prepilin peptidase) / N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	0.970
Q7C_2228	Q7C_2227	Q7C_2228	Q7C_2227	Type IV fimbrial assembly, ATPase PilB; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: type IV-A pilus assembly ATPase PilB.	Type IV fimbrial assembly protein PilC; PFAM: Bacterial type II secretion system protein F domain.	0.987
Q7C_2228	coaE	Q7C_2228	Q7C_2225	Type IV fimbrial assembly, ATPase PilB; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: type IV-A pilus assembly ATPase PilB.	Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	0.788
Q7C_2228	zapD	Q7C_2228	Q7C_2224	Type IV fimbrial assembly, ATPase PilB; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: type IV-A pilus assembly ATPase PilB.	Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.	0.788
coaE	Q7C_2226	Q7C_2225	Q7C_2226	Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Leader peptidase (Prepilin peptidase) / N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	0.880
coaE	Q7C_2227	Q7C_2225	Q7C_2227	Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Type IV fimbrial assembly protein PilC; PFAM: Bacterial type II secretion system protein F domain.	0.811
coaE	Q7C_2228	Q7C_2225	Q7C_2228	Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Type IV fimbrial assembly, ATPase PilB; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: type IV-A pilus assembly ATPase PilB.	0.788
coaE	zapD	Q7C_2225	Q7C_2224	Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.	0.976
zapD	Q7C_2226	Q7C_2224	Q7C_2226	Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.	Leader peptidase (Prepilin peptidase) / N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	0.832
zapD	Q7C_2227	Q7C_2224	Q7C_2227	Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.	Type IV fimbrial assembly protein PilC; PFAM: Bacterial type II secretion system protein F domain.	0.800
zapD	Q7C_2228	Q7C_2224	Q7C_2228	Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.	Type IV fimbrial assembly, ATPase PilB; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: type IV-A pilus assembly ATPase PilB.	0.788
zapD	coaE	Q7C_2224	Q7C_2225	Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.	Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	0.976