(18 nodes) beta-Alanine metabolism network (Paraburkholderia sprentiae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APA85083.1	Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
	APA85085.1	Dihydropyrimidine dehydrogenase subunit B; NADH-dependent; catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
	APA85086.1	Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)
	APA85360.1	Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
	APA85463.1	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (479 aa)
	panC	Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (277 aa)
	panD	Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (128 aa)
	APA85566.1	Aspartate aminotransferase family protein; Catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
	APA87016.1	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
	APA87042.1	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (285 aa)
	APA85972.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
	APA87066.1	Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (517 aa)
	APA86538.1	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
	APA87518.1	Betaine-aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (483 aa)
	APA87763.1	Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)
	APA87796.1	Aldehyde dehydrogenase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (499 aa)
	APA88331.1	Aspartate aminotransferase family protein; Catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (442 aa)
	APA88711.1	Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)

Your Current Organism:

Paraburkholderia sprentiae

NCBI taxonomy Id: 754502
Other names: Burkholderia sp. WSM5005, Burkholderia sprentiae WSM5005, P. sprentiae WSM5005, Paraburkholderia sprentiae WSM5005

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APA85083.1	APA85085.1	BJG93_06580	BJG93_06590	Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydropyrimidine dehydrogenase subunit B; NADH-dependent; catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
APA85083.1	APA85086.1	BJG93_06580	BJG93_06595	Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.986
APA85083.1	APA87763.1	BJG93_06580	BJG93_20145	Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.917
APA85085.1	APA85083.1	BJG93_06590	BJG93_06580	Dihydropyrimidine dehydrogenase subunit B; NADH-dependent; catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
APA85085.1	APA85086.1	BJG93_06590	BJG93_06595	Dihydropyrimidine dehydrogenase subunit B; NADH-dependent; catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
APA85085.1	APA87763.1	BJG93_06590	BJG93_20145	Dihydropyrimidine dehydrogenase subunit B; NADH-dependent; catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.994
APA85086.1	APA85083.1	BJG93_06595	BJG93_06580	Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.986
APA85086.1	APA85085.1	BJG93_06595	BJG93_06590	Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydropyrimidine dehydrogenase subunit B; NADH-dependent; catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
APA85086.1	APA87763.1	BJG93_06595	BJG93_20145	Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.957
APA85360.1	APA85463.1	BJG93_08165	BJG93_08780	Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology.	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.	0.921
APA85360.1	APA85566.1	BJG93_08165	BJG93_09345	Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate aminotransferase family protein; Catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.924
APA85360.1	APA85972.1	BJG93_08165	BJG93_11615	Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.906
APA85360.1	APA87066.1	BJG93_08165	BJG93_12890	Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology.	Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology.	0.901
APA85360.1	APA87518.1	BJG93_08165	BJG93_18705	Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology.	Betaine-aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.	0.918
APA85360.1	APA87796.1	BJG93_08165	BJG93_20415	Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology.	Aldehyde dehydrogenase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.	0.908
APA85360.1	APA88331.1	BJG93_08165	BJG93_23445	Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate aminotransferase family protein; Catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.924
APA85360.1	APA88711.1	BJG93_08165	BJG93_25745	Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology.	Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology.	0.905
APA85463.1	APA85360.1	BJG93_08780	BJG93_08165	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.	Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology.	0.921
APA85463.1	APA85566.1	BJG93_08780	BJG93_09345	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.	Aspartate aminotransferase family protein; Catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.901
APA85463.1	APA85972.1	BJG93_08780	BJG93_11615	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.812