STRINGSTRING
ADY57738.1 ADY57738.1 yidC yidC secF secF ADY58299.1 ADY58299.1 tatA tatA ADY58478.1 ADY58478.1 secA secA ADY59353.1 ADY59353.1 ADY59354.1 ADY59354.1 ADY59356.1 ADY59356.1 ADY59358.1 ADY59358.1 ADY59359.1 ADY59359.1 ADY59360.1 ADY59360.1 ADY59365.1 ADY59365.1 ftsY ftsY ADY59616.1 ADY59616.1 secY secY tatC tatC ADY60403.1 ADY60403.1 ADY60404.1 ADY60404.1 ADY60405.1 ADY60405.1 ADY60779.1 ADY60779.1 ADY60780.1 ADY60780.1 ADY60781.1 ADY60781.1 ADY60783.1 ADY60783.1 ADY60788.1 ADY60788.1 secA-2 secA-2 ADY61930.1 ADY61930.1 ffh ffh secA-3 secA-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADY57738.1COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR001482; KEGG: plm:Plim_0753 type II secretion system protein E; PFAM: Type II secretion system protein E; SPTR: Type II secretion system protein E; PFAM: Type II/IV secretion system protein. (433 aa)
yidCMembrane protein oxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (680 aa)
secFProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (968 aa)
ADY58299.1Preprotein translocase, YajC subunit; InterPro IPR003849; KEGG: cte:CT0065 hypothetical protein; PFAM: YajC; SPTR: Putative uncharacterized protein; TIGRFAM: YajC; PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit. (126 aa)
tatASec-independent translocation protein mttA/Hcf106; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (72 aa)
ADY58478.1InterPro IPR003369; KEGG: plm:Plim_2724 twin-arginine translocation protein, TatA/E family subunit; PFAM: Bacterial sec-independent translocation protein mttA/Hcf106; SPTR: Twin-arginine translocation protein, TatA/E family subunit; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family. (99 aa)
secAProtein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (1189 aa)
ADY59353.1Type VI secretion ATPase, ClpV1 family; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterPro IPR017729: IPR003593: IPR004176: IPR003959: IPR 013093: IPR019489; KEGG: azl:AZL_017820 chaperone protein; PFAM: ATPase, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: AAA ATPase, central region:Clp, N terminal:Clp, N terminal; TIGRFAM: ATPase, type VI secretion system, ClpV1; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activit [...] (884 aa)
ADY59354.1Type VI secretion system effector, Hcp1 family; COGs: COG3157 Hemolysin-coregulated protein (uncharacterized); InterPro IPR017728: IPR008514; KEGG: cvi:CV_3977 hypothetical protein; PFAM: Virulence factor, secretion apparatus; SPTR: Putative uncharacterized protein; TIGRFAM: Type VI secretion system effector, Hcp1; PFAM: Protein of unknown function (DUF796); TIGRFAM: type VI secretion system effector, Hcp1 family. (165 aa)
ADY59356.1Protein of unknown function DUF796; COGs: COG3157 Hemolysin-coregulated protein (uncharacterized); InterPro IPR008514; KEGG: azo:azo1305 hypothetical protein; PFAM: Virulence factor, secretion apparatus; SPTR: Putative cytoplasmic protein; PFAM: Protein of unknown function (DUF796); TIGRFAM: type VI secretion system effector, Hcp1 family. (199 aa)
ADY59358.1Protein of unknown function DUF796; COGs: COG3157 Hemolysin-coregulated protein (uncharacterized); InterPro IPR008514; KEGG: psp:PSPPH_4224 hypothetical protein; PFAM: Virulence factor, secretion apparatus; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF796); TIGRFAM: type VI secretion system effector, Hcp1 family. (191 aa)
ADY59359.1Type VI secretion system effector, Hcp1 family; COGs: COG3157 Hemolysin-coregulated protein (uncharacterized); InterPro IPR017728: IPR008514; KEGG: cvi:CV_3977 hypothetical protein; PFAM: Virulence factor, secretion apparatus; SPTR: Type VI secretion system effector, Hcp1 family; TIGRFAM: Type VI secretion system effector, Hcp1; PFAM: Protein of unknown function (DUF796); TIGRFAM: type VI secretion system effector, Hcp1 family. (174 aa)
ADY59360.1Type VI secretion system Vgr family protein; COGs: COG3501 conserved hypothetical protein; InterPro IPR017847: IPR006533; KEGG: azc:AZC_2592 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Rhs element Vgr protein, subgroup; Rhs element Vgr protein; PFAM: Phage late control gene D protein (GPD); Phage-related baseplate assembly protein; TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein. (654 aa)
ADY59365.1Type IV / VI secretion system, DotU; COGs: COG3455 conserved hypothetical protein; InterPro IPR017732; KEGG: psl:Psta_1825 hypothetical protein; PFAM: Type IV / VI secretion system, DotU; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2077); TIGRFAM: type IV / VI secretion system protein, DotU family. (213 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (313 aa)
ADY59616.1Preprotein translocase, SecE subunit; InterPro IPR005807: IPR001901; KEGG: plm:Plim_0437 preprotein translocase, SecE subunit; PFAM: Protein secE/sec61-gamma protein; SPTR: Putative uncharacterized protein; TIGRFAM: SecE subunit of protein translocation complex; PFAM: SecE/Sec61-gamma subunits of protein translocation complex; TIGRFAM: preprotein translocase, SecE subunit, bacterial; Belongs to the SecE/SEC61-gamma family. (147 aa)
secYProtein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (455 aa)
tatCSec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. (375 aa)
ADY60403.1COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR003593: IPR001482; KEGG: psl:Psta_2137 type II secretion system protein E; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core; SPTR: Putative secretion pathway ATPase; PFAM: Type II/IV secretion system protein. (416 aa)
ADY60404.1Type II secretion system F domain protein; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076; KEGG: sml:Smlt2740 putative general secretion pathway protein F; PFAM: Type II secretion system F domain; SPTR: General secretion pathway protein F; PFAM: Bacterial type II secretion system protein F domain. (337 aa)
ADY60405.1Type II secretion system F domain protein; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076; KEGG: mmr:Mmar10_0383 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: Type IV pilus assembly protein PilC; PFAM: Bacterial type II secretion system protein F domain. (402 aa)
ADY60779.1Type II secretion system protein E (GspE); COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR007831: IPR001482: IPR003593; KEGG: plm:Plim_4189 type II secretion system protein E; PFAM: Type II secretion system protein E; General secretory system II, protein E, N-terminal; SMART: ATPase, AAA+ type, core; SPTR: General secretion pathway protein E; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: general secretory pathway protein E. (564 aa)
ADY60780.1Type II secretion system F domain protein; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076; KEGG: plm:Plim_0156 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: Type 4 fimbrial assembly protein pilC; PFAM: Bacterial type II secretion system protein F domain. (402 aa)
ADY60781.1General secretion pathway protein G; InterPro IPR012902: IPR013545: IPR010054; KEGG: plm:Plim_2895 general secretion pathway protein G; PFAM: Type II secretion system protein G; Prepilin-type cleavage/methylation, N-terminal; SPTR: General secretion pathway protein G; TIGRFAM: General secretion pathway protein G; Prepilin-type cleavage/methylation, N-terminal; PFAM: Prokaryotic N-terminal methylation motif; Bacterial type II secretion system protein G; TIGRFAM: general secretion pathway protein G; prepilin-type N-terminal cleavage/methylation domain. (157 aa)
ADY60783.1InterPro IPR012902; KEGG: plm:Plim_3637 type II secretion system protein I/J; SPTR: Putative uncharacterized protein; TIGRFAM: general secretion pathway protein I. (144 aa)
ADY60788.1Type II and III secretion system protein; COGs: COG1450 Type II secretory pathway component PulD; InterPro IPR005644: IPR004846; KEGG: plm:Plim_3688 type II and III secretion system protein; PFAM: Type II/III secretion system; NolW-like; SPTR: General secretion pathway protein D (Precursor); PFAM: Bacterial type II/III secretion system short domain; Bacterial type II and III secretion system protein; TIGRFAM: general secretion pathway protein D. (1315 aa)
secA-2Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (642 aa)
ADY61930.1Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (187 aa)
ffhSignal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (495 aa)
secA-3Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (640 aa)
Your Current Organism:
Rubinisphaera brasiliensis
NCBI taxonomy Id: 756272
Other names: Planctomyces brasiliensis ATCC 49424, Planctomyces brasiliensis DSM 5305, Planctomyces brasiliensis str. DSM 5305, Planctomyces brasiliensis strain DSM 5305, R. brasiliensis DSM 5305, Rubinisphaera brasiliensis DSM 5305
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