(69 nodes) Glycine, serine and threonine metabolism network (Arthrobotrys oligospora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AOL_s00076g97	PALP domain-containing protein. (391 aa)
	AOL_s00215g912	PNPLA domain-containing protein. (752 aa)
	AOL_s00215g710	Uncharacterized protein; Belongs to the peptidase M24B family. (609 aa)
	AOL_s00215g666	D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (472 aa)
	AOL_s00215g351	Threonine dehydratase. (546 aa)
	AOL_s00215g122	Aspartokinase. (530 aa)
	AOL_s00215g2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (505 aa)
	AOL_s00215g553	Uncharacterized protein. (354 aa)
	AOL_s00215g391	DAO domain-containing protein. (482 aa)
	AOL_s00188g90	Aminotran_5 domain-containing protein. (505 aa)
	AOL_s00173g316	PNPLA domain-containing protein. (642 aa)
	AOL_s00173g279	PALP domain-containing protein. (382 aa)
	AOL_s00170g51	CBM1 domain-containing protein. (386 aa)
	AOL_s00140g78	Uncharacterized protein. (207 aa)
	AOL_s00140g77	PNPLA domain-containing protein. (452 aa)
	AOL_s00117g57	DAO domain-containing protein. (465 aa)
	AOL_s00097g465	AMP_N domain-containing protein. (511 aa)
	AOL_s00097g201	Uncharacterized protein. (533 aa)
	AOL_s00097g114	DAO domain-containing protein. (357 aa)
	AOL_s00097g64	PALP domain-containing protein. (336 aa)
	AOL_s00091g5	PNPLA domain-containing protein. (933 aa)
	AOL_s00083g474	CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (259 aa)
	AOL_s00083g174	Uncharacterized protein. (321 aa)
	AOL_s00083g67	Uncharacterized protein. (354 aa)
	AOL_s00081g334	Tryptophan synthase. (729 aa)
	AOL_s00081g86	Uncharacterized protein. (429 aa)
	AOL_s00080g354	Arginine N-methyltransferase 2; S-adenosyl-L-methionine-dependent protein-arginine N- methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12. (435 aa)
	AOL_s00079g462	SurE domain-containing protein. (335 aa)
	AOL_s00079g447	Zn(2)-C6 fungal-type domain-containing protein. (919 aa)
	AOL_s00079g363	Aminotran_1_2 domain-containing protein. (670 aa)
	AOL_s00079g354	Amine oxidase. (697 aa)
	AOL_s00079g329	Uncharacterized protein. (1384 aa)
	AOL_s00079g141	Uncharacterized protein. (337 aa)
	AOL_s00079g68	Semialdhyde_dh domain-containing protein. (358 aa)
	AOL_s00078g533	Zn(2)-C6 fungal-type domain-containing protein. (680 aa)
	AOL_s00078g256	Uncharacterized protein. (416 aa)
	AOL_s00078g176	RyR domain-containing protein. (193 aa)
	AOL_s00078g174	Uncharacterized protein. (848 aa)
	AOL_s00078g82	Homoserine dehydrogenase. (370 aa)
	AOL_s00076g614	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (480 aa)
	AOL_s00076g507	D-ser_dehydrat domain-containing protein. (434 aa)
	AOL_s00076g374	Uncharacterized protein. (415 aa)
	AOL_s00076g162	PNPLA domain-containing protein. (682 aa)
	AOL_s00076g161	Uncharacterized protein. (497 aa)
	AOL_s00054g735	PNPLA domain-containing protein. (704 aa)
	AOL_s00054g731	PNPLA domain-containing protein. (943 aa)
	AOL_s00054g639	Uncharacterized protein. (514 aa)
	AOL_s00054g637	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (469 aa)
	AOL_s00054g616	Dihydrolipoyl dehydrogenase. (510 aa)
	AOL_s00054g583	NB-ARC domain-containing protein. (482 aa)
	AOL_s00054g540	PNPLA domain-containing protein. (436 aa)
	AOL_s00043g791	SH3 domain-containing protein. (805 aa)
	AOL_s00043g662	Beta_elim_lyase domain-containing protein. (391 aa)
	AOL_s00043g502	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (524 aa)
	AOL_s00043g445	AMP_N domain-containing protein. (459 aa)
	AOL_s00043g433	Amine oxidase. (703 aa)
	AOL_s00043g288	DAO domain-containing protein. (466 aa)
	AOL_s00043g230	Uncharacterized protein. (482 aa)
	AOL_s00043g159	Uncharacterized protein. (1118 aa)
	AOL_s00043g102	Uncharacterized protein. (73 aa)
	AOL_s00007g161	PNPLA domain-containing protein. (189 aa)
	AOL_s00007g126	GMC_OxRdtase_N domain-containing protein. (672 aa)
	AOL_s00006g551	Uncharacterized protein. (115 aa)
	AOL_s00006g356	PNPLA domain-containing protein. (694 aa)
	AOL_s00006g107	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
	AOL_s00004g510	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (176 aa)
	AOL_s00004g393	AMP_N domain-containing protein. (500 aa)
	AOL_s00004g339	Uncharacterized protein. (247 aa)
	AOL_s00004g37	Uncharacterized protein. (477 aa)

Your Current Organism:

Arthrobotrys oligospora

NCBI taxonomy Id: 756982
Other names: A. oligospora ATCC 24927, Arthrobotrys oligospora ATCC 24927

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOL_s00004g339	AOL_s00054g637	G1WYH9	G1X6Z3	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.537
AOL_s00004g339	AOL_s00054g639	G1WYH9	G1X6Z5	Uncharacterized protein.	Uncharacterized protein.	0.829
AOL_s00004g339	AOL_s00076g374	G1WYH9	G1X9Z1	Uncharacterized protein.	Uncharacterized protein.	0.463
AOL_s00004g339	AOL_s00078g533	G1WYH9	G1XC86	Uncharacterized protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.463
AOL_s00004g339	AOL_s00079g141	G1WYH9	G1XD38	Uncharacterized protein.	Uncharacterized protein.	0.775
AOL_s00004g339	AOL_s00079g447	G1WYH9	G1XDR2	Uncharacterized protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.463
AOL_s00004g339	AOL_s00215g2	G1WYH9	G1XT73	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.537
AOL_s00004g339	AOL_s00215g666	G1WYH9	G1XUK8	Uncharacterized protein.	D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.463
AOL_s00004g37	AOL_s00004g393	G1WXM7	G1WYN2	Uncharacterized protein.	AMP_N domain-containing protein.	0.410
AOL_s00004g37	AOL_s00004g510	G1WXM7	G1WYZ9	Uncharacterized protein.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.544
AOL_s00004g37	AOL_s00043g102	G1WXM7	G1X329	Uncharacterized protein.	Uncharacterized protein.	0.683
AOL_s00004g37	AOL_s00043g159	G1WXM7	G1X386	Uncharacterized protein.	Uncharacterized protein.	0.565
AOL_s00004g37	AOL_s00043g230	G1WXM7	G1X3F7	Uncharacterized protein.	Uncharacterized protein.	0.506
AOL_s00004g37	AOL_s00043g445	G1WXM7	G1X421	Uncharacterized protein.	AMP_N domain-containing protein.	0.410
AOL_s00004g37	AOL_s00043g662	G1WXM7	G1X4N8	Uncharacterized protein.	Beta_elim_lyase domain-containing protein.	0.493
AOL_s00004g37	AOL_s00043g791	G1WXM7	G1X517	Uncharacterized protein.	SH3 domain-containing protein.	0.683
AOL_s00004g37	AOL_s00054g616	G1WXM7	G1X6X2	Uncharacterized protein.	Dihydrolipoyl dehydrogenase.	0.506
AOL_s00004g37	AOL_s00054g637	G1WXM7	G1X6Z3	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.541
AOL_s00004g37	AOL_s00076g614	G1WXM7	G1XAF6	Uncharacterized protein.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.685
AOL_s00004g37	AOL_s00079g363	G1WXM7	G1XDH8	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.460