(26 nodes) Valine, leucine and isoleucine biosynthesis network (Arthrobotrys oligospora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AOL_s00004g283	Acetolactate synthase. (693 aa)
	AOL_s00043g588	Uncharacterized protein. (493 aa)
	AOL_s00054g60	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (768 aa)
	AOL_s00054g787	Uncharacterized protein. (341 aa)
	AOL_s00075g7	Acetolactate synthase. (631 aa)
	AOL_s00075g156	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (408 aa)
	AOL_s00076g97	PALP domain-containing protein. (391 aa)
	AOL_s00076g583	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (430 aa)
	AOL_s00078g171	HET domain-containing protein. (596 aa)
	AOL_s00080g146	Uncharacterized protein. (231 aa)
	AOL_s00080g165	Uncharacterized protein. (611 aa)
	AOL_s00080g217	Uncharacterized protein. (409 aa)
	AOL_s00083g404	Uncharacterized protein. (351 aa)
	AOL_s00097g85	Uncharacterized protein. (293 aa)
	AOL_s00097g354	Pyruvate carboxyltransferase domain-containing protein. (617 aa)
	AOL_s00097g439	Uncharacterized protein. (316 aa)
	AOL_s00097g505	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (364 aa)
	AOL_s00140g9	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (625 aa)
	AOL_s00140g93	HET domain-containing protein. (1311 aa)
	AOL_s00169g170	Uncharacterized protein. (362 aa)
	AOL_s00173g267	Uncharacterized protein. (522 aa)
	AOL_s00173g279	PALP domain-containing protein. (382 aa)
	AOL_s00188g25	ACT domain-containing protein. (309 aa)
	AOL_s00188g113	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (423 aa)
	AOL_s00193g188	Uncharacterized protein. (359 aa)
	AOL_s00215g351	Threonine dehydratase. (546 aa)

Your Current Organism:

Arthrobotrys oligospora

NCBI taxonomy Id: 756982
Other names: A. oligospora ATCC 24927, Arthrobotrys oligospora ATCC 24927

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOL_s00004g283	AOL_s00043g588	G1WYC3	G1X4G4	Acetolactate synthase.	Uncharacterized protein.	0.864
AOL_s00004g283	AOL_s00054g60	G1WYC3	G1X5B6	Acetolactate synthase.	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.887
AOL_s00004g283	AOL_s00054g787	G1WYC3	G1X7E3	Acetolactate synthase.	Uncharacterized protein.	0.823
AOL_s00004g283	AOL_s00075g156	G1WYC3	G1X8F7	Acetolactate synthase.	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.	0.897
AOL_s00004g283	AOL_s00076g583	G1WYC3	G1XAC5	Acetolactate synthase.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.841
AOL_s00004g283	AOL_s00076g97	G1WYC3	G1X8Z0	Acetolactate synthase.	PALP domain-containing protein.	0.821
AOL_s00004g283	AOL_s00078g171	G1WYC3	G1XB74	Acetolactate synthase.	HET domain-containing protein.	0.617
AOL_s00004g283	AOL_s00080g146	G1WYC3	G1XEB1	Acetolactate synthase.	Uncharacterized protein.	0.596
AOL_s00004g283	AOL_s00080g165	G1WYC3	G1XED0	Acetolactate synthase.	Uncharacterized protein.	0.857
AOL_s00004g283	AOL_s00080g217	G1WYC3	G1XEI2	Acetolactate synthase.	Uncharacterized protein.	0.596
AOL_s00004g283	AOL_s00083g404	G1WYC3	G1XHC3	Acetolactate synthase.	Uncharacterized protein.	0.596
AOL_s00004g283	AOL_s00097g354	G1WYC3	G1XJ27	Acetolactate synthase.	Pyruvate carboxyltransferase domain-containing protein.	0.749
AOL_s00004g283	AOL_s00097g439	G1WYC3	G1XJB2	Acetolactate synthase.	Uncharacterized protein.	0.596
AOL_s00004g283	AOL_s00097g505	G1WYC3	G1XJH8	Acetolactate synthase.	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	0.686
AOL_s00004g283	AOL_s00097g85	G1WYC3	G1XIA8	Acetolactate synthase.	Uncharacterized protein.	0.596
AOL_s00004g283	AOL_s00140g9	G1WYC3	G1XM40	Acetolactate synthase.	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.749
AOL_s00004g283	AOL_s00140g93	G1WYC3	G1XMC4	Acetolactate synthase.	HET domain-containing protein.	0.617
AOL_s00004g283	AOL_s00169g170	G1WYC3	G1XMW7	Acetolactate synthase.	Uncharacterized protein.	0.596
AOL_s00004g283	AOL_s00173g267	G1WYC3	G1XP99	Acetolactate synthase.	Uncharacterized protein.	0.617
AOL_s00004g283	AOL_s00173g279	G1WYC3	G1XPB1	Acetolactate synthase.	PALP domain-containing protein.	0.814