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folD folD ribA ribA folE folE add add hisI hisI ribD ribD dcd dcd ADJ64490.1 ADJ64490.1 folE2 folE2 tadA tadA purH purH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (281 aa)
ribAGTP cyclohydrolase II protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (228 aa)
folEGTP cyclohydrolase I protein. (254 aa)
addAdenosine deaminase protein; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (352 aa)
hisIphosphoribosyl-AMP cyclohydrolase protein; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (166 aa)
ribDDiaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (354 aa)
dcdDeoxycytidine triphosphate deaminase protein; Catalyzes the deamination of dCTP to dUTP. (189 aa)
ADJ64490.1Conserved hypothetical protein; S - Function unknown; Belongs to the multicopper oxidase YfiH/RL5 family. (248 aa)
folE2Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. (303 aa)
tadACytosine/adenosine deaminases protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (185 aa)
purHBifunctional enzyme: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase transmembrane protein. (523 aa)
Your Current Organism:
Herbaspirillum seropedicae
NCBI taxonomy Id: 757424
Other names: H. seropedicae SmR1, Herbaspirillum seropedicae SmR1, Herbaspirillum seropedicae str. SmR1, Herbaspirillum seropedicae strain SmR1
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