STRINGSTRING
ntrY ntrY ADJ61539.1 ADJ61539.1 czcS czcS ptsI ptsI ackA ackA coaE coaE proB proB ADJ61910.1 ADJ61910.1 anmK anmK thiD thiD pfkB pfkB xylB xylB thrB thrB bacA bacA bacA-2 bacA-2 ADJ62066.1 ADJ62066.1 nadK nadK ADJ62137.1 ADJ62137.1 cheY cheY ADJ62141.1 ADJ62141.1 folK folK ADJ62164.1 ADJ62164.1 ADJ62172.1 ADJ62172.1 pgk pgk pykA pykA ADJ62245.1 ADJ62245.1 ADJ62357.1 ADJ62357.1 dctS dctS glpK glpK rbsK rbsK dgoK dgoK araB araB ADJ62609.1 ADJ62609.1 lpxK lpxK adk adk vsrA vsrA vsrB vsrB ADJ62750.1 ADJ62750.1 ppk ppk phoR phoR ADJ62861.1 ADJ62861.1 ADJ62881.1 ADJ62881.1 ribF ribF thrB-2 thrB-2 ADJ63015.1 ADJ63015.1 envZ envZ cheA cheA ADJ63260.1 ADJ63260.1 ADJ63456.1 ADJ63456.1 ADJ63466.1 ADJ63466.1 relA relA ADJ63513.1 ADJ63513.1 ADJ63611.1 ADJ63611.1 gmk gmk lysC lysC risS risS pyrH pyrH ADJ63693.1 ADJ63693.1 ppsA ppsA ADJ63698.1 ADJ63698.1 rbsK-2 rbsK-2 ADJ63801.1 ADJ63801.1 iolC iolC baeS baeS ADJ63952.1 ADJ63952.1 hydH hydH cheA-2 cheA-2 ADJ63984.1 ADJ63984.1 ADJ63989.1 ADJ63989.1 ADJ63991.1 ADJ63991.1 ADJ63992.1 ADJ63992.1 ADJ63994.1 ADJ63994.1 ygiY ygiY ADJ64039.1 ADJ64039.1 ADJ64070.1 ADJ64070.1 ADJ64071.1 ADJ64071.1 ADJ64094.1 ADJ64094.1 tmk tmk ADJ64132.1 ADJ64132.1 cobP cobP ADJ64227.1 ADJ64227.1 ADJ64260.1 ADJ64260.1 ndk ndk cheA-3 cheA-3 cheA-4 cheA-4 czcS-2 czcS-2 cheA-5 cheA-5 ntrB ntrB ADJ64614.1 ADJ64614.1 selD selD ADJ64654.1 ADJ64654.1 dctB dctB thiL thiL ADJ64861.1 ADJ64861.1 ADJ64863.1 ADJ64863.1 ADJ64873.1 ADJ64873.1 xylB-2 xylB-2 ADJ64987.1 ADJ64987.1 glk glk ADJ65096.1 ADJ65096.1 narX narX rfaE rfaE cmk cmk ADJ65206.1 ADJ65206.1 ADJ65211.1 ADJ65211.1 ADJ65213.1 ADJ65213.1 ADJ65229.1 ADJ65229.1 kdpD kdpD ADJ65317.1 ADJ65317.1 thiD-2 thiD-2 ubiB ubiB ptsN ptsN ptsK ptsK ADJ65386.1 ADJ65386.1 ipk ipk prsA prsA ADJ65430.1 ADJ65430.1 ADJ65641.1 ADJ65641.1 aroBK aroBK argB argB coaX coaX pckA pckA ADJ65808.1 ADJ65808.1 ADJ65850.1 ADJ65850.1 ADJ65863.1 ADJ65863.1 ADJ65880.1 ADJ65880.1 fucK fucK ADJ65990.1 ADJ65990.1 tctE tctE ADJ66013.1 ADJ66013.1 nagK nagK baeS-2 baeS-2 ADJ66101.1 ADJ66101.1 ADJ66198.1 ADJ66198.1 ADJ66202.1 ADJ66202.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ntrYTwo component sensor histidine kinase protein. (760 aa)
ADJ61539.1Homoserine kinase type II protein. (333 aa)
czcSSensor protein; Member of a two-component regulatory system. (467 aa)
ptsIPhosphoenolpyruvate-protein phosphotransferase transmembrane protein; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (595 aa)
ackAAcetate kinase protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
coaEdephospho-CoA kinase protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (206 aa)
proBGamma-glutamyl kinase protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (372 aa)
ADJ61910.1Sugar kinase ribokinase family protein. (311 aa)
anmKanhydro-N-acetylmuramic acid kinase protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (375 aa)
thiDPhosphomethylpyrimidine kinase protein. (288 aa)
pfkBFructokinase protein. (301 aa)
xylBSugar (pentulose and hexulose) kinase protein. (490 aa)
thrBHomoserine kinase protein; Belongs to the pseudomonas-type ThrB family. (318 aa)
bacABacitracin resistance undecaprenol kinase 2 protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (284 aa)
bacA-2Bacitracin resistance undecaprenol kinase 2 protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (290 aa)
ADJ62066.1Multi-sensor hybrid histidine kinase protein. (845 aa)
nadKInorganic polyphosphate/ATP-NAD kinase protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (305 aa)
ADJ62137.1Deoxynucleoside kinase protein. (213 aa)
cheYTwo-component system sensor histidine kinase/response regulator protein. (122 aa)
ADJ62141.1Chemotaxis histidine kinase protein. (725 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase protein. (161 aa)
ADJ62164.1Two component transmembrane sensor histidine kinase protein. (390 aa)
ADJ62172.1Sensor histidine kinase. (202 aa)
pgk3-phosphoglycerate kinase protein; Belongs to the phosphoglycerate kinase family. (396 aa)
pykAPyruvate kinase II protein; Belongs to the pyruvate kinase family. (477 aa)
ADJ62245.1Panthothenate kinase protein. (204 aa)
ADJ62357.1ATPase/kinase protein. (161 aa)
dctSC4-dicarboxylate transport sensor (histidine kinase) protein. (674 aa)
glpKGlycerol kinase protein; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (495 aa)
rbsKRibokinase protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (319 aa)
dgoK2-keto-3-deoxygalactonate kinase protein. (319 aa)
araBD-ribulose/ribitol kinase protein. (548 aa)
ADJ62609.1Gluconokinase protein; Belongs to the FGGY kinase family. (520 aa)
lpxKTetraacyldisaccharide 4'-kinase protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (345 aa)
adkAdenylate kinase (ATP-AMP transphosphorylase) protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa)
vsrATransmembrane sensor histidine kinase protein. (677 aa)
vsrBComposite two-component regulatory (sensor kinase and response regulator hybrid) transcription regulator protein. (604 aa)
ADJ62750.1Hpt sensor hybrid histidine kinase protein. (723 aa)
ppkPolyphosphate kinase protein; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (704 aa)
phoRPhosphate regulon two-component sensor kinase transcription regulator protein. (436 aa)
ADJ62861.1Two component transmembrane sensor histidine kinase protein. (508 aa)
ADJ62881.1Two component hybrid sensor histidine kinase/response regulator protein. (916 aa)
ribFRiboflavin biosynthesis protein; Belongs to the ribF family. (325 aa)
thrB-2Homoserine kinase type II protein; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (336 aa)
ADJ63015.12-ketogluconate kinase protein. (313 aa)
envZTwo component sensor histidine kinase protein. (465 aa)
cheAChemotaxis histidine kinase protein. (837 aa)
ADJ63260.1Sugar kinase,ribokinase family protein. (308 aa)
ADJ63456.1Two component sensor histidine kinase protein. (401 aa)
ADJ63466.1Transmembrane sensor histidine kinase transcription regulator protein. (464 aa)
relA(p)ppGpp synthetase I (GTP pyrophosphokinase) protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (749 aa)
ADJ63513.1Glycerate kinase protein; Belongs to the glycerate kinase type-1 family. (387 aa)
ADJ63611.1Signal transduction histidine kinase protein. (560 aa)
gmkGuanylate kinase (GMP kinase) protein; Essential for recycling GMP and indirectly, cGMP. (212 aa)
lysCAspartokinase protein; Belongs to the aspartokinase family. (428 aa)
risSOxidative stress resistance two component transmembrane sensor histidine kinase protein. (455 aa)
pyrHUridylate kinase protein; Catalyzes the reversible phosphorylation of UMP to UDP. (238 aa)
ADJ63693.1ATP-binding protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (280 aa)
ppsAPhosphoenolpyruvate synthase/pyruvate phosphate dikinase protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa)
ADJ63698.1Two component sensor histidine kinase protein. (473 aa)
rbsK-2Sugar kinase protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (299 aa)
ADJ63801.1PAS/PAC sensor hybrid histidine kinase response regulator protein. (688 aa)
iolCTransferase kinase protein. (657 aa)
baeSSignal transduction histidine kinase protein. (446 aa)
ADJ63952.1PAS/PAC sensor hybrid histidine kinase protein. (552 aa)
hydHTwo component sensor histidine kinase protein. (460 aa)
cheA-2Chemotaxis histidine kinase protein. (808 aa)
ADJ63984.1Two component heavy metal sensor histidine kinase protein; Member of a two-component regulatory system. (467 aa)
ADJ63989.1Two component hybrid sensor histidine kinase/response regulator protein. (1278 aa)
ADJ63991.1Bacteriophytochrome (light-regulated signal transduction histidine kinase) protein. (732 aa)
ADJ63992.1Two component sensor histidine kinase protein. (289 aa)
ADJ63994.1Two component sensor histidine kinase protein. (535 aa)
ygiYTransmembrane sensor histidine kinase transcription regulator protein. (468 aa)
ADJ64039.1Sphingosine kinase/eukaryotic diacylglycerol kinase protein. (339 aa)
ADJ64070.1Multi-sensor signal transduction histidine kinase protein. (475 aa)
ADJ64071.1Two component sensor histidine kinase protein. (633 aa)
ADJ64094.1Transmembrane sensor histidine kinase transcription regulator protein. (443 aa)
tmkThymidylate kinase protein; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (202 aa)
ADJ64132.1Sensor histidine kinase/response regulator protein. (1145 aa)
cobPBifunctional enzyme: cobinamide kinase/cobinamide phosphate guanylyltransferase protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (204 aa)
ADJ64227.1Sensory transduction histidine kinase protein. (706 aa)
ADJ64260.1Signal transduction histidine kinase protein. (356 aa)
ndkNucleoside-diphosphate kinase protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa)
cheA-3Signal-transducing histidine kinase CheA protein. (697 aa)
cheA-4Two component hybrid sensor histidine kinase/response regulator protein. (775 aa)
czcS-2Cobalt/zinc/cadmium resistance two component transmembrane sensor histidine kinase protein; Member of a two-component regulatory system. (475 aa)
cheA-5Chemotaxis CheA protein. (638 aa)
ntrBNitrogen regulation (sensor histidine kinase) transcription regulator protein. (366 aa)
ADJ64614.1Sensor histidine kinase (domains REC and Hpt) protein. (233 aa)
selDSelenophosphate synthase protein; Synthesizes selenophosphate from selenide and ATP. (348 aa)
ADJ64654.1Adenylate kinase and related kinases protein. (189 aa)
dctBC4-dicarboxylate transport sensor kinase transcription regulator protein. (600 aa)
thiLThiamine-monophosphate kinase protein; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (321 aa)
ADJ64861.1Two component hybrid sensor histidine kinase/response regulator protein. (1160 aa)
ADJ64863.1Periplasmic sensor signal transduction histidine kinase protein. (459 aa)
ADJ64873.1Transmembrane sensor kinase transcription regulator protein. (459 aa)
xylB-2D-xylulose kinase protein. (493 aa)
ADJ64987.1Two component sensor histidine kinase protein. (401 aa)
glkGlucokinase protein; Belongs to the bacterial glucokinase family. (333 aa)
ADJ65096.1Transmembrane sensor histidine kinase-like ATPase protein. (380 aa)
narXTransmembrane nitrate/nitrite sensor histidine kinase transcription regulator protein. (650 aa)
rfaEADP-heptose synthase protein. (310 aa)
cmkCytidylate kinase protein. (222 aa)
ADJ65206.1Two component sensor histidine kinase protein. (556 aa)
ADJ65211.1Two component transmembrane sensor histidine kinase protein. (454 aa)
ADJ65213.1Two component hybrid sensor histidine kinase/response regulator protein. (1524 aa)
ADJ65229.1Two component sensor histidine kinase protein. (120 aa)
kdpDTwo component sensor histidine kinase protein. (939 aa)
ADJ65317.1CheA-like histidine kinase protein. (744 aa)
thiD-2Phosphomethylpyrimidine kinase protein. (282 aa)
ubiBUbiquinone biosynthesis transmembrane protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (524 aa)
ptsNNitrogen PTS system EIIA component; Nitrogen regulatory IIA (Enzyme IIA-NTR) (Phosphotransferase enzyme II, A component) transcription regulator protein. (157 aa)
ptsKHpr kinase and phosphatase protein; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (312 aa)
ADJ65386.1P-loop-containing kinase protein; Displays ATPase and GTPase activities. (300 aa)
ipk4-diphosphocytidyl-2C-methyl-D-erythritol kinase protein; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (289 aa)
prsAPhosphoribosylpyrophosphate synthetase protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa)
ADJ65430.1Two component transmembrane sensor histidine kinase protein. (361 aa)
ADJ65641.1ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (160 aa)
aroBKBifunctional enzyme: 3-dehydroquinate synthase/shikimate kinase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (596 aa)
argBAcetylglutamate kinase protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (297 aa)
coaXTranscription regulation accessory factor transcription regulator protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (258 aa)
pckAPhosphoenolpyruvate carboxykinase protein; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (622 aa)
ADJ65808.1Ser protein kinase protein. (640 aa)
ADJ65850.1Two component sensor histidine kinase protein. (479 aa)
ADJ65863.1Transmembrane sensor histidine kinase protein. (444 aa)
ADJ65880.1Galactokinase/mevalonate kinase protein. (332 aa)
fucKL-fuculokinase protein. (478 aa)
ADJ65990.1PAS/PAC HisKA ATPase_c domains containing sensor signal transduction histidine kinase protein. (524 aa)
tctETwo component sensor histidine kinase protein. (485 aa)
ADJ66013.1Sensor histidine kinase protein. (478 aa)
nagKN-acetylglucosamine kinase protein. (308 aa)
baeS-2Two-component system sensor histidine kinase protein. (475 aa)
ADJ66101.1Two component sensor histidine kinase protein. (517 aa)
ADJ66198.1Two component sensor histidine kinase protein. (467 aa)
ADJ66202.1Two component sensor histidine kinase protein. (492 aa)
Your Current Organism:
Herbaspirillum seropedicae
NCBI taxonomy Id: 757424
Other names: H. seropedicae SmR1, Herbaspirillum seropedicae SmR1, Herbaspirillum seropedicae str. SmR1, Herbaspirillum seropedicae strain SmR1
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