STRINGSTRING
argB argB aspS aspS lpxC lpxC aroE aroE acpD acpD cheW cheW cheR cheR recA recA groEL1 groEL1 edd edd ompR ompR ADJ63189.1 ADJ63189.1 cheW-2 cheW-2 cheR-2 cheR-2 cheA cheA gntP gntP exaC exaC epsG epsG cheR-3 cheR-3 cheZ cheZ flgE flgE flgF flgF flgH flgH flgK flgK flgL flgL fliM fliM fliL fliL fliG fliG fliT fliT fliS fliS fliD fliD fliC fliC ADJ63600.1 ADJ63600.1 acpD-2 acpD-2 phbC phbC cheA-2 cheA-2 gcvT gcvT argC argC cheW-3 cheW-3 cheA-3 cheA-3 motB motB flhC flhC flhD flhD acpD-3 acpD-3 phbC-2 phbC-2 cheA-4 cheA-4 cheW-4 cheW-4 cheR-4 cheR-4 cheZ-2 cheZ-2 cheA-5 cheA-5 ADJ64595.1 ADJ64595.1 glnA glnA cheR-5 cheR-5 fliD-2 fliD-2 flgE-2 flgE-2 hutH hutH aroE-2 aroE-2 ADJ65245.1 ADJ65245.1 argC-2 argC-2 fabG-12 fabG-12 paaF paaF acpD-4 acpD-4 pcaH pcaH pcaG pcaG paaB paaB ompR-2 ompR-2 groEL groEL acpD-5 acpD-5 xylF xylF ompR-3 ompR-3 hutH-2 hutH-2 flgH-2 flgH-2 ADJ66230.1 ADJ66230.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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argBAcetylglutamate kinase protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (297 aa)
aspSaspartyl-tRNA synthetase protein; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (599 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (311 aa)
aroEShikimate 5-dehydrogenase protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (271 aa)
acpDAcyl carrier protein phosphodiesterase protein; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. (205 aa)
cheWPositive regulator of CheA protein activity protein. (194 aa)
cheRChemotaxis protein methyltransferase protein; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (277 aa)
recARecombinase A protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (351 aa)
groEL1Chaperonin GroEL (HSP60) protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (549 aa)
edd6-phosphogluconate dehydratase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (623 aa)
ompRTwo component transcription regulator protein. (248 aa)
ADJ63189.14-hydroxyphenylpyruvate dioxygenase and related hemolysins protein. (364 aa)
cheW-2Chemotaxis signal transduction protein. (516 aa)
cheR-2Chemotaxis protein methyltransferase protein; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (280 aa)
cheAChemotaxis histidine kinase protein. (837 aa)
gntPHigh-affinity gluconate transporter (GNT-III system) transmembrane protein. (450 aa)
exaCNAD+ dependent acetaldehyde dehydrogenase protein; Belongs to the aldehyde dehydrogenase family. (506 aa)
epsGEPS biosynthesis protein. (293 aa)
cheR-3Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (290 aa)
cheZChemotaxis phosphatase, CheZ protein; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). (216 aa)
flgEFlagellar basal-body rod FlgE protein. (432 aa)
flgFFlagellar basal body rod FlgF protein; Belongs to the flagella basal body rod proteins family. (245 aa)
flgHFlagellar basal-body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. (219 aa)
flgKFlagellar hook-associated FlgK protein; Belongs to the flagella basal body rod proteins family. (778 aa)
flgLFlagellar hook-filament junction protein, N-terminus flagellin protein. (377 aa)
fliMFlagellar motor switch FliM protein. (334 aa)
fliLFlagellar FliL transmembrane protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. (171 aa)
fliGFlagellar motor switch FliG protein. (331 aa)
fliTFlagellar FliT protein. (109 aa)
fliSFlagellin-specific chaperone FliS protein. (154 aa)
fliDFlagellar hook-associated 2 protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. (690 aa)
fliCFlagellin protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (362 aa)
ADJ63600.1Gluconate transporter family protein. (456 aa)
acpD-2Acyl-carrier-protein phosphodiesterase protein; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. (202 aa)
phbCPoly-beta-hydroxyalkanoate synthase protein. (590 aa)
cheA-2Chemotaxis histidine kinase protein. (808 aa)
gcvTGlycine cleavage T (aminomethyltransferase) protein; Belongs to the GcvT family. (360 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (309 aa)
cheW-3CheW chemotaxis protein, positive regulator of CheA protein activity. (168 aa)
cheA-3Signal-transducing histidine kinase CheA protein. (697 aa)
motBFlagellar motor component protein. (312 aa)
flhCFlagellar transcription activator regulator protein; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (200 aa)
flhDFlagellar transcription activator protein; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (105 aa)
acpD-3Acyl carrier protein phosphodiesterase protein; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. (208 aa)
phbC-2Poly(3-hydroxyalkanoate) synthetase protein. (588 aa)
cheA-4Two component hybrid sensor histidine kinase/response regulator protein. (775 aa)
cheW-4Chemotaxis signal transduction protein. (211 aa)
cheR-4Methyltransferase of chemotaxis proteins protein. (433 aa)
cheZ-2Chemotaxis phosphatase protein; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). (246 aa)
cheA-5Chemotaxis CheA protein. (638 aa)
ADJ64595.1NADH:flavin oxidoreductase/NADH oxidase family protein. (366 aa)
glnAGlutamine synthetase protein. (471 aa)
cheR-5Protein-glutamate methyltransferase chemotaxis response regulator protein. (283 aa)
fliD-2Flagellar capping protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. (680 aa)
flgE-2Flagellar hook protein. (420 aa)
hutHHistidine ammonia-lyase protein. (526 aa)
aroE-2Shikimate 5-dehydrogenase protein. (281 aa)
ADJ65245.14-hydroxyphenylpyruvate dioxygenase protein. (293 aa)
argC-2N-acetyl-gamma-glutamyl-phosphate reductase protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (345 aa)
fabG-12Short-chain alcohol dehydrogenase protein. (254 aa)
paaFenoyl-CoA hydratase protein; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
acpD-4[acyl-carrier-protein] phosphodiesterase protein; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. (203 aa)
pcaHProtocatechuate 3,4-dioxygenase beta chain protein. (230 aa)
pcaGProtocatechuate 3,4-dioxygenase alpha chain protein. (170 aa)
paaBPhenylacetic acid degradation protein. (94 aa)
ompR-2Two component transcription regulator protein. (240 aa)
groELChaperonin GroEL protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (540 aa)
acpD-5Acyl carrier protein phosphodiesterase protein; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. (208 aa)
xylFABC-type D-xylose transport system, periplasmic component protein. (338 aa)
ompR-3Two component transcription regulator protein. (224 aa)
hutH-2Histidine ammonia-lyase protein. (542 aa)
flgH-2Flagellar basal body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. (221 aa)
ADJ66230.1NAD-dependent aldehyde dehydrogenase protein; Belongs to the aldehyde dehydrogenase family. (472 aa)
Your Current Organism:
Herbaspirillum seropedicae
NCBI taxonomy Id: 757424
Other names: H. seropedicae SmR1, Herbaspirillum seropedicae SmR1, Herbaspirillum seropedicae str. SmR1, Herbaspirillum seropedicae strain SmR1
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