STRINGSTRING
ADJ61550.1 ADJ61550.1 secE secE secY secY secB secB gspG gspG ADJ61776.1 ADJ61776.1 ADJ61805.1 ADJ61805.1 secA secA ffh ffh ADJ62255.1 ADJ62255.1 ADJ62256.1 ADJ62256.1 ADJ62258.1 ADJ62258.1 ADJ62262.1 ADJ62262.1 clpB clpB vgr vgr ADJ62277.1 ADJ62277.1 ADJ62282.1 ADJ62282.1 hrcV hrcV hrcN hrcN hrcQ hrcQ hrcR hrcR hrcS hrcS hrpX hrpX hrcU hrcU hrcJ hrcJ hrcC hrcC gspE gspE ADJ62458.1 ADJ62458.1 yajC yajC secD secD secF secF tolC-3 tolC-3 hlyD hlyD cyaB cyaB ADJ64886.1 ADJ64886.1 ADJ65498.1 ADJ65498.1 clpB-3 clpB-3 ADJ65506.1 ADJ65506.1 ADJ65510.1 ADJ65510.1 ADJ65512.1 ADJ65512.1 tatC tatC tatB tatB tatA tatA ftsY ftsY vgr-2 vgr-2 yidC yidC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADJ61550.1VGR-related protein. (913 aa)
secEPreprotein translocase SecE subunit transmembrane protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (126 aa)
secYPreprotein translocase SecY transmembrane protein; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (443 aa)
secBPreprotein translocase subunit SecB protein; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (164 aa)
gspGGeneral secretion pathway protein. (183 aa)
ADJ61776.1VGR-related protein. (966 aa)
ADJ61805.1VGR-related protein. (912 aa)
secAPreprotein translocase SecA subunit protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (918 aa)
ffhSignal recognition particle subunit SRP54 protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the indiv [...] (456 aa)
ADJ62255.1VGR-related protein. (954 aa)
ADJ62256.1Transmembrane protein. (263 aa)
ADJ62258.1Transmembrane protein. (174 aa)
ADJ62262.1Conserved hypothetical protein; S - Function unknown. (163 aa)
clpBClpA/B-type chaperone protein; Belongs to the ClpA/ClpB family. (893 aa)
vgrVGR-related type VI secretion system protein. (944 aa)
ADJ62277.1Transmembrane protein. (1291 aa)
ADJ62282.1VGR-related protein. (982 aa)
hrcVType III secretion HrcV transmembrane protein. (695 aa)
hrcNType III secretion ATP synthase protein. (460 aa)
hrcQType III secretion system protein. (400 aa)
hrcRType III secretion HrcR transmembrane protein. (220 aa)
hrcSType III secretion HrcS protein. (87 aa)
hrpXType III secretion HprX protein. (262 aa)
hrcUType III secretion HrcU transmembrane protein. (371 aa)
hrcJType III secretion HrcJ lipoprotein. (292 aa)
hrcCType II/III HrcC transmembrane protein. (693 aa)
gspEGeneral secretion pathway protein E. (541 aa)
ADJ62458.1VGR-related protein. (928 aa)
yajCPreprotein translocase transmembrane protein; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (110 aa)
secDExport membrane protein SecD transmembrane; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (634 aa)
secFPreprotein translocase subunit SecF protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (314 aa)
tolC-3Outer membrane channel lipoprotein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. (484 aa)
hlyDHemolysin secretion-related transmembrane protein. (447 aa)
cyaBABC-type bacteriocin/lantibiotic (cyclolysin-type) secretion transporter protein. (726 aa)
ADJ64886.1VGR-related protein. (824 aa)
ADJ65498.1Transmembrane protein. (1266 aa)
clpB-3ClpA/B-type chaperone ATPase protein; Belongs to the ClpA/ClpB family. (889 aa)
ADJ65506.1Conserved hypothetical protein; S - Function unknown. (163 aa)
ADJ65510.1Transmembrane protein. (209 aa)
ADJ65512.1Type IV / VI secretion system transmembrane protein. (257 aa)
tatCSec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (256 aa)
tatBSec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (173 aa)
tatASec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (67 aa)
ftsYSignal recognition particle GTPase involved in cell division protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (321 aa)
vgr-2VGR-related type VI secretion system protein. (886 aa)
yidCInner-membrane transmembrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (542 aa)
Your Current Organism:
Herbaspirillum seropedicae
NCBI taxonomy Id: 757424
Other names: H. seropedicae SmR1, Herbaspirillum seropedicae SmR1, Herbaspirillum seropedicae str. SmR1, Herbaspirillum seropedicae strain SmR1
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