(87 nodes) Ether lipid metabolism network (Scyliorhinus torazame)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	scyTo_0002412	SGNH_hydro domain-containing protein. (229 aa)
	scyTo_0002345	Uncharacterized protein. (296 aa)
	scyTo_0016819	Spondin domain-containing protein. (331 aa)
	scyTo_0015848	Uncharacterized protein. (629 aa)
	scyTo_0018506	PlsC domain-containing protein. (234 aa)
	scyTo_0017384	Spondin domain-containing protein. (142 aa)
	scyTo_0017385	Uncharacterized protein. (232 aa)
	scyTo_0015972	LisH domain-containing protein; Belongs to the UDP-glycosyltransferase family. (1353 aa)
	scyTo_0019540	Lipase_GDSL domain-containing protein. (443 aa)
	scyTo_0016983	PA2c domain-containing protein. (580 aa)
	scyTo_0006571	Uncharacterized protein. (355 aa)
	scyTo_0006468	Phospholipase A2. (763 aa)
	scyTo_0025132	Uncharacterized protein. (67 aa)
	scyTo_0025184	Uncharacterized protein. (59 aa)
	scyTo_0025113	Uncharacterized protein. (263 aa)
	scyTo_0025164	Uncharacterized protein. (159 aa)
	scyTo_0014242	Uncharacterized protein. (212 aa)
	scyTo_0011415	WD_REPEATS_REGION domain-containing protein. (118 aa)
	scyTo_0011462	Uncharacterized protein. (351 aa)
	scyTo_0000039	acidPPc domain-containing protein. (283 aa)
	scyTo_0000043	PA2c domain-containing protein. (654 aa)
	PAFAH1B1	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
	scyTo_0008885	Lipase_GDSL domain-containing protein. (380 aa)
	scyTo_0019081	Uncharacterized protein. (191 aa)
	scyTo_0021986	Uncharacterized protein. (494 aa)
	scyTo_0023506	Uncharacterized protein. (466 aa)
	scyTo_0023729	PLD phosphodiesterase domain-containing protein. (111 aa)
	scyTo_0018577	cPLA2_C2 domain-containing protein. (248 aa)
	scyTo_0018583	Uncharacterized protein. (657 aa)
	scyTo_0019169	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (416 aa)
	scyTo_0017530	Lipase_GDSL domain-containing protein. (302 aa)
	scyTo_0023749	Uncharacterized protein. (117 aa)
	scyTo_0024697	Uncharacterized protein. (401 aa)
	scyTo_0025183	PX domain-containing protein. (92 aa)
	scyTo_0001907	Uncharacterized protein. (239 aa)
	scyTo_0002099	TMEM189_B_dmain domain-containing protein. (286 aa)
	scyTo_0026113	Uncharacterized protein. (141 aa)
	scyTo_0025427	Uncharacterized protein. (193 aa)
	scyTo_0021540	PLD phosphodiesterase domain-containing protein. (301 aa)
	scyTo_0022648	Uncharacterized protein. (126 aa)
	scyTo_0023213	Uncharacterized protein. (144 aa)
	scyTo_0019606	Uncharacterized protein. (109 aa)
	scyTo_0018049	PLD phosphodiesterase domain-containing protein. (501 aa)
	scyTo_0023099	Uncharacterized protein. (61 aa)
	scyTo_0014620	CRAL-TRIO domain-containing protein. (376 aa)
	scyTo_0004368	Uncharacterized protein. (419 aa)
	scyTo_0004369	TMEM189_B_dmain domain-containing protein. (278 aa)
	scyTo_0009624	Uncharacterized protein. (262 aa)
	scyTo_0011551	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (306 aa)
	scyTo_0003819	UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa)
	scyTo_0003749	Uncharacterized protein. (185 aa)
	scyTo_0003551	Uncharacterized protein. (226 aa)
	scyTo_0003552	Uncharacterized protein. (142 aa)
	scyTo_0004581	Phospholipase A(2). (186 aa)
	scyTo_0000794	Phospholipase A(2). (144 aa)
	scyTo_0004609	acidPPc domain-containing protein. (290 aa)
	scyTo_0007594	PLA2c domain-containing protein. (184 aa)
	scyTo_0004819	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (658 aa)
	scyTo_0000448	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (386 aa)
	scyTo_0000449	NYD-SP28_assoc domain-containing protein. (663 aa)
	scyTo_0007821	EF-hand domain-containing protein. (444 aa)
	scyTo_0012388	GP-PDE domain-containing protein. (374 aa)
	scyTo_0005430	Uncharacterized protein. (425 aa)
	scyTo_0013934	Uncharacterized protein. (848 aa)
	scyTo_0004917	Platelet-activating factor acetylhydrolase. (469 aa)
	scyTo_0008012	Uncharacterized protein. (186 aa)
	scyTo_0001605	Uncharacterized protein. (758 aa)
	scyTo_0025265	Uncharacterized protein. (177 aa)
	scyTo_0005970	Uncharacterized protein. (197 aa)
	scyTo_0001398	acidPPc domain-containing protein. (270 aa)
	scyTo_0010677	Uncharacterized protein. (349 aa)
	scyTo_0008446	Uncharacterized protein. (409 aa)
	scyTo_0008419	acidPPc domain-containing protein. (317 aa)
	scyTo_0012405	Phospholipase A(2). (159 aa)
	scyTo_0012674	Phospholipase A(2). (207 aa)
	scyTo_0021782	PLA2c domain-containing protein. (163 aa)
	scyTo_0022078	PA2c domain-containing protein. (155 aa)
	scyTo_0006812	Uncharacterized protein. (349 aa)
	scyTo_0006941	Uncharacterized protein. (718 aa)
	scyTo_0000725	Lipase_GDSL domain-containing protein. (260 aa)
	scyTo_0005116	Spondin domain-containing protein. (483 aa)
	scyTo_0005159	Uncharacterized protein. (800 aa)
	scyTo_0013870	PLD phosphodiesterase domain-containing protein. (506 aa)
	scyTo_0010399	Uncharacterized protein. (87 aa)
	scyTo_0018484	Uncharacterized protein. (471 aa)
	scyTo_0015182	Uncharacterized protein. (161 aa)
	scyTo_0000793	Phospholipase A(2). (147 aa)

Your Current Organism:

Scyliorhinus torazame

NCBI taxonomy Id: 75743
Other names: S. torazame, cloudy catshark

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PAFAH1B1	scyTo_0002345	A0A401PGA7	A0A401PIY5	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Uncharacterized protein.	0.688
PAFAH1B1	scyTo_0002412	A0A401PGA7	A0A401PJD7	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	SGNH_hydro domain-containing protein.	0.995
PAFAH1B1	scyTo_0004917	A0A401PGA7	A0A401NZ59	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Platelet-activating factor acetylhydrolase.	0.908
PAFAH1B1	scyTo_0005159	A0A401PGA7	A0A401P3A6	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Uncharacterized protein.	0.826
PAFAH1B1	scyTo_0005430	A0A401PGA7	A0A401P7T3	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Uncharacterized protein.	0.908
PAFAH1B1	scyTo_0005970	A0A401PGA7	A0A401PEH7	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Uncharacterized protein.	0.832
PAFAH1B1	scyTo_0007594	A0A401PGA7	A0A401NVH4	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	PLA2c domain-containing protein.	0.747
PAFAH1B1	scyTo_0008012	A0A401PGA7	A0A401P235	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Uncharacterized protein.	0.834
PAFAH1B1	scyTo_0011415	A0A401PGA7	A0A401NMB9	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	WD_REPEATS_REGION domain-containing protein.	0.707
PAFAH1B1	scyTo_0012674	A0A401PGA7	A0A401NGM9	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Phospholipase A(2).	0.837
PAFAH1B1	scyTo_0013934	A0A401PGA7	A0A401P7T2	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Uncharacterized protein.	0.675
PAFAH1B1	scyTo_0015848	A0A401PGA7	A0A401PZN2	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Uncharacterized protein.	0.751
PAFAH1B1	scyTo_0018577	A0A401PGA7	A0A401PYJ1	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	cPLA2_C2 domain-containing protein.	0.747
PAFAH1B1	scyTo_0019606	A0A401PGA7	A0A401Q328	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	Uncharacterized protein.	0.751
PAFAH1B1	scyTo_0021782	A0A401PGA7	A0A401Q6X2	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	PLA2c domain-containing protein.	0.747
scyTo_0000039	scyTo_0000448	A0A401NNN7	A0A401NXQ2	acidPPc domain-containing protein.	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.886
scyTo_0000039	scyTo_0001398	A0A401NNN7	A0A401PCN7	acidPPc domain-containing protein.	acidPPc domain-containing protein.	0.888
scyTo_0000039	scyTo_0004609	A0A401NNN7	A0A401NU79	acidPPc domain-containing protein.	acidPPc domain-containing protein.	0.917
scyTo_0000039	scyTo_0004819	A0A401NNN7	A0A401NXL7	acidPPc domain-containing protein.	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.	0.513
scyTo_0000039	scyTo_0006812	A0A401NNN7	A0A401NGP8	acidPPc domain-containing protein.	Uncharacterized protein.	0.871