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NCTC8284_01817 NCTC8284_01817 rpmH rpmH ndk_1 ndk_1 raiA raiA rpmF rpmF infA infA rpsF rpsF rpsR rpsR rplI rplI GCA_000730685_00603 GCA_000730685_00603 rplU_1 rplU_1 rpmE rpmE rpmL rpmL rplT rplT rpsI rpsI rplM rplM rplY rplY prfB_2 prfB_2 rpsO rpsO rpmB rpmB rpmG rpmG era_1 era_1 arfA arfA efp efp rpsQ rpsQ rpmC rpmC rplP rplP rpsC rpsC rplV_2 rplV_2 rpsS rpsS rplB rplB rplW_2 rplW_2 rplD_1 rplD_1 rplC_1 rplC_1 rpsJ rpsJ rplA rplA rplK_2 rplK_2 rplQ rplQ GCA_000730685_01713 GCA_000730685_01713 rpmJ rpmJ rplO rplO rpmD rpmD rplR rplR rplF rplF rpsH rpsH rpsN rpsN rplE_1 rplE_1 rplX_2 rplX_2 rplN rplN tufA1_1 tufA1_1 rplJ rplJ rplL rplL rpsL rpsL rpsG_2 rpsG_2 fusA fusA GCA_000730685_02028 GCA_000730685_02028 selB_3 selB_3 rpsU rpsU rpsB_1 rpsB_1 GCA_000730685_02155 GCA_000730685_02155 rplS rplS GCA_000730685_02208 GCA_000730685_02208 GCA_000730685_02220 GCA_000730685_02220
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCTC8284_01817Unannotated protein. (253 aa)
rpmHUnannotated protein; Belongs to the bacterial ribosomal protein bL34 family. (44 aa)
ndk_1Unannotated protein; Belongs to the NDK family. (140 aa)
raiAUnannotated protein. (106 aa)
rpmFUnannotated protein; Belongs to the bacterial ribosomal protein bL32 family. (56 aa)
infAUnannotated protein; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa)
rpsFUnannotated protein; Binds together with S18 to 16S ribosomal RNA. (125 aa)
rpsRUnannotated protein; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (76 aa)
rplIUnannotated protein; Binds to the 23S rRNA. (149 aa)
GCA_000730685_00603Unannotated protein. (85 aa)
rplU_1Unannotated protein; This protein binds to 23S rRNA in the presence of protein L20. (122 aa)
rpmEUnannotated protein; Binds the 23S rRNA. (70 aa)
rpmLUnannotated protein; Belongs to the bacterial ribosomal protein bL35 family. (65 aa)
rplTUnannotated protein; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (117 aa)
rpsIUnannotated protein; Belongs to the universal ribosomal protein uS9 family. (130 aa)
rplMUnannotated protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa)
rplYUnannotated protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. (95 aa)
prfB_2Unannotated protein. (354 aa)
rpsOUnannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa)
rpmBUnannotated protein; Belongs to the bacterial ribosomal protein bL28 family. (78 aa)
rpmGUnannotated protein; Belongs to the bacterial ribosomal protein bL33 family. (56 aa)
era_1Unannotated protein. (302 aa)
arfAUnannotated protein. (81 aa)
efpUnannotated protein; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. (188 aa)
rpsQUnannotated protein; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (85 aa)
rpmCUnannotated protein; Belongs to the universal ribosomal protein uL29 family. (63 aa)
rplPUnannotated protein; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa)
rpsCUnannotated protein; Belongs to the universal ribosomal protein uS3 family. (235 aa)
rplV_2Unannotated protein; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (110 aa)
rpsSUnannotated protein; Belongs to the universal ribosomal protein uS19 family. (91 aa)
rplBUnannotated protein; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (273 aa)
rplW_2Unannotated protein. (99 aa)
rplD_1Unannotated protein. (200 aa)
rplC_1Unannotated protein; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (208 aa)
rpsJUnannotated protein; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa)
rplAUnannotated protein; Belongs to the universal ribosomal protein uL1 family. (229 aa)
rplK_2Unannotated protein. (142 aa)
rplQUnannotated protein. (127 aa)
GCA_000730685_01713Unannotated protein. (118 aa)
rpmJUnannotated protein; Belongs to the bacterial ribosomal protein bL36 family. (37 aa)
rplOUnannotated protein; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (144 aa)
rpmDUnannotated protein. (59 aa)
rplRUnannotated protein; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (117 aa)
rplFUnannotated protein; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa)
rpsHUnannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rpsNUnannotated protein; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
rplE_1Unannotated protein. (179 aa)
rplX_2Unannotated protein; Belongs to the universal ribosomal protein uL24 family. (103 aa)
rplNUnannotated protein; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (123 aa)
tufA1_1Unannotated protein; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa)
rplJUnannotated protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (163 aa)
rplLUnannotated protein. (123 aa)
rpsLUnannotated protein; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (124 aa)
rpsG_2Unannotated protein. (156 aa)
fusAUnannotated protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (700 aa)
GCA_000730685_02028Unannotated protein. (394 aa)
selB_3Unannotated protein. (621 aa)
rpsUUnannotated protein; Belongs to the bacterial ribosomal protein bS21 family. (71 aa)
rpsB_1Unannotated protein; Belongs to the universal ribosomal protein uS2 family. (242 aa)
GCA_000730685_02155Unannotated protein. (82 aa)
rplSUnannotated protein; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (116 aa)
GCA_000730685_02208Unannotated protein. (87 aa)
GCA_000730685_02220Unannotated protein. (70 aa)
Your Current Organism:
Rodentibacter pneumotropicus
NCBI taxonomy Id: 758
Other names: ATCC 35149, CCUG 12398, CIP 66.16, DSM 21403, JCM 14074, LMG 4224, LMG:4224, NCTC 8141, Pasteurella pneumotropica, Pasteurellaceae bacterium Ac63, R. pneumotropicus
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