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| | ligA | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (681 aa) |
| | LSS_20476 | acyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa) |
| | mtnP | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (287 aa) |
| | LSS_20239 | HD family phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa) |
| | rplY | 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (211 aa) |
| | ppnP | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (104 aa) |
| | LSS_19840 | tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (344 aa) |
| | xseB | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (96 aa) |
| | LSS_19513 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1194 aa) |
| | LSS_19488 | Fe-S cluster assembly protein SufB; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa) |
| | LSS_19393 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (342 aa) |
| | LSS_19373 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (231 aa) |
| | LSS_19368 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (238 aa) |
| | folD | 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa) |
| | cysS | cysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (474 aa) |
| | LSS_18658 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family. (182 aa) |
| | dnaK | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (641 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa) |
| | LSS_18389 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (115 aa) |
| | LSS_18144 | Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa) |
| | LSS_17999 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (188 aa) |
| | nusG | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (181 aa) |
| | rplL | 50S ribosomal protein L7; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (126 aa) |
| | LSS_17755 | Exodeoxyribonuclease V subunit beta; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1051 aa) |
| | LSS_17630 | Aspartokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (405 aa) |
| | LSS_17590 | CMP-KDO synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (524 aa) |
| | valS | valyl-tRNA synthase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (882 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (426 aa) |
| | thiM | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (266 aa) |
| | LSS_17180 | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (469 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (374 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (477 aa) |
| | LSS_16681 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (516 aa) |
| | hslV | Peptidase; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. (180 aa) |
| | hslU | ATP-dependent protease; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (475 aa) |
| | LSS_16566 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (306 aa) |
| | LSS_16561 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (186 aa) |
| | LSS_16461 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (334 aa) |
| | pyrB | Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (320 aa) |
| | LSS_15966 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1498 aa) |
| | LSS_15931 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (393 aa) |
| | sucC | malate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (390 aa) |
| | rpsI | 30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family. (132 aa) |
| | LSS_15666 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0234 family. (163 aa) |
| | prmC | N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (286 aa) |
| | LSS_15576 | Helicase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (932 aa) |
| | LSS_15536 | ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa) |
| | LSS_15526 | Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (413 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (307 aa) |
| | LSS_15346 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (318 aa) |
| | LSS_15211 | Metal-dependent molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa) |
| | LSS_14647 | Pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa) |
| | LSS_14602 | Plastocyanin; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (222 aa) |
| | LSS_14561 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (413 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (281 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (173 aa) |
| | LSS_14376 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (280 aa) |
| | LSS_14316 | Transcriptional antiterminator; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa) |
| | aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (235 aa) |
| | ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (341 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (202 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (635 aa) |
| | trpA | Tryptophan synthase susbunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (264 aa) |
| | LSS_14059 | UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (241 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa) |
| | rpsB | 30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family. (294 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (267 aa) |
| | LSS_13914 | acetoacetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (689 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (219 aa) |
| | ribBA | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (401 aa) |
| | LSS_13834 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa) |
| | LSS_13829 | Pyrimidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (336 aa) |
| | mgsA | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (147 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (405 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (503 aa) |
| | LSS_13389 | Heptosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa) |
| | LSS_13344 | Glycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FGGY kinase family. (515 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (331 aa) |
| | LSS_13094 | UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa) |
| | LSS_12974 | Bifunctional translation initiation inhibitor; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa) |
| | LSS_12684 | Endoflagellar biosynthesis chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (208 aa) |
| | purH | Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa) |
| | LSS_12634 | Pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (253 aa) |
| | lysS | lysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (495 aa) |
| | LSS_12322 | poly-A polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (432 aa) |
| | LSS_12222 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa) |
| | hisD | Histidinal dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (426 aa) |
| | clpX | ATP-dependent protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (420 aa) |
| | LSS_11650 | N-acetyl neuraminic (sialic) acid synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa) |
| | LSS_11530 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (758 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (324 aa) |
| | LSS_11255 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa) |
| | gcvP | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (964 aa) |
| | gcvT | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (386 aa) |
| | LSS_11160 | Aldehyde-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa) |
| | rplS | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (140 aa) |
| | LSS_10923 | Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (220 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (315 aa) |
| | hprK | Aldolase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (318 aa) |
| | kdsA | 2-dehydro-3-deoxyphosphooctonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. (287 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (540 aa) |
| | LSS_10848 | ADP-heptose synthase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (158 aa) |
| | LSS_10843 | ADP-heptose synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (313 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (178 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (235 aa) |
| | LSS_10208 | Pyrimidine reductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (210 aa) |
| | LSS_10173 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa) |
| | ppa | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (178 aa) |
| | LSS_10023 | Chemotaxis protein R; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa) |
| | LSS_09953 | 1-aminocyclopropane-1-carboxylate deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa) |
| | map | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (252 aa) |
| | LSS_09549 | Phosphomannomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (600 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (358 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (848 aa) |
| | bioD | ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (221 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (496 aa) |
| | LSS_09354 | BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (89 aa) |
| | LSS_09349 | BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (75 aa) |
| | LSS_09334 | Carboxylate-amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa) |
| | gshA | Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (520 aa) |
| | leuD | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (206 aa) |
| | LSS_09219 | GMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (603 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily. (271 aa) |
| | LSS_08864 | S-adenosylmethionine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa) |
| | speH | Hypothetical protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (128 aa) |
| | LSS_08759 | Aconitate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (757 aa) |
| | LSS_08699 | Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (486 aa) |
| | LSS_08619 | 5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (307 aa) |
| | LSS_08609 | HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa) |
| | LSS_08594 | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (317 aa) |
| | LSS_08534 | Flavoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa) |
| | LSS_07729 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (556 aa) |
| | ahcY | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (436 aa) |
| | LSS_07634 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1247 aa) |
| | LSS_07564 | HD family phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa) |
| | LSS_07384 | Pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa) |
| | LSS_07229 | Stringent starvation protein B-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa) |
| | cobQ | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (865 aa) |
| | LSS_07084 | Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa) |
| | LSS_06689 | Adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa) |
| | LSS_06390 | NTP phosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (196 aa) |
| | LSS_06335 | tRNA pseudouridine synthase D; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa) |
| | LSS_06260 | ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (380 aa) |
| | engB | GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (221 aa) |
| | LSS_06050 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa) |
| | acsA | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (661 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (387 aa) |
| | LSS_05693 | Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (485 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa) |
| | LSS_05468 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (460 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (290 aa) |
| | LSS_05298 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa) |
| | LSS_05046 | 3-ketoacyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | LSS_04966 | LOG family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family. (191 aa) |
| | LSS_04626 | 23S rRNA pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (328 aa) |
| | LSS_04546 | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa) |
| | LSS_04491 | Valine--pyruvate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa) |
| | LSS_04416 | DNA mismatch repair protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (610 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (333 aa) |
| | LSS_04254 | Fumarylacetoacetate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa) |
| | LSS_04179 | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa) |
| | nusB | Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (138 aa) |
| | proB | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (289 aa) |
| | LSS_03364 | 2-oxoglutarate dehydrogenase E1; Derived by automated computational analysis using gene prediction method: Protein Homology. (922 aa) |
| | thrS | threonyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (639 aa) |
| | cmk | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (376 aa) |
| | LSS_02714 | Peptidase M3; Derived by automated computational analysis using gene prediction method: Protein Homology. (651 aa) |
| | LSS_02609 | Chromosome partitioning protein ParA; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa) |
| | LSS_02539 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa) |
| | LSS_02524 | 2-nitropropane dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa) |
| | hfq | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. (82 aa) |
| | LSS_02242 | Endoflagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein. (269 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (560 aa) |
| | LSS_01787 | Ribosomal large subunit pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa) |
| | LSS_01602 | Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa) |
| | LSS_01567 | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (155 aa) |
| | LSS_01557 | ADP-heptosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa) |
| | smpB | Single-stranded DNA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome t [...] (161 aa) |
| | pcnB | tRNA nucleotidyltransferase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (491 aa) |
| | LSS_01209 | Nitrogen regulatory protein P-II; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa) |
| | glmS | Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (610 aa) |
| | LSS_01169 | Phosphomannomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa) |
| | LSS_01049 | ATP phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa) |
| | rpmC | 50S ribosomal protein L29; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL29 family. (94 aa) |
| | rpsQ | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (89 aa) |
| | rpsE | 30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (168 aa) |
| | rplO | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (180 aa) |
| | infA | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa) |
| | rpsK | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (136 aa) |
| | LSS_00175 | Ferritin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Dps family. (160 aa) |
| | LSS_00155 | HD family phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (508 aa) |
