17 items (Chaetomium thermophilum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	CTHT_0003200	AMP deaminase-like protein. (1142 aa)
	CTHT_0010500	Formyltetrahydrofolate deformylase-like protein. (285 aa)
	CTHT_0031290	Phosphoribosylformylglycinamidine synthase-like protein. (1355 aa)
	CTHT_0023100	Adenosine kinase-like protein. (348 aa)
	CTHT_0024020	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (482 aa)
	CTHT_0026290	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (423 aa)
	CTHT_0036600	GMP synthase [glutamine-hydrolyzing]-like protein. (538 aa)
	CTHT_0044900	Xanthine phosphoribosyltransferase-like protein. (208 aa)
	CTHT_0049640	Uncharacterized protein. (108 aa)
	CTHT_0054820	Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (614 aa)
	CTHT_0057880	Putative bifunctional purine biosynthesis protein. (593 aa)
	CTHT_0058720	Pribosyltran domain-containing protein. (229 aa)
	CTHT_0062440	Amidophosphoribosyltransferase. (576 aa)
	CTHT_0064510	Phosphoribosylaminoimidazole-succinocarboxamide synthase-like protein. (302 aa)
	CTHT_0060430	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (543 aa)
	CTHT_0069060	Phosphoribosylglycinamide formyltransferase-like protein. (306 aa)
	CTHT_0070180	Putative bifunctional purine biosynthetic protein. (786 aa)

Your Current Organism:

Chaetomium thermophilum

NCBI taxonomy Id: 759272
Other names: C. thermophilum var. thermophilum DSM 1495, Chaetomium thermophilum var. thermophilum DSM 1495

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTHT_0003200	CTHT_0023100	G0RZJ7	G0S4P9	AMP deaminase-like protein.	Adenosine kinase-like protein.	0.969
CTHT_0003200	CTHT_0024020	G0RZJ7	G0S543	AMP deaminase-like protein.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.956
CTHT_0003200	CTHT_0026290	G0RZJ7	G0S6I0	AMP deaminase-like protein.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.945
CTHT_0003200	CTHT_0031290	G0RZJ7	G0S4K1	AMP deaminase-like protein.	Phosphoribosylformylglycinamidine synthase-like protein.	0.422
CTHT_0003200	CTHT_0036600	G0RZJ7	G0S7K1	AMP deaminase-like protein.	GMP synthase [glutamine-hydrolyzing]-like protein.	0.537
CTHT_0003200	CTHT_0049640	G0RZJ7	G0SBB6	AMP deaminase-like protein.	Uncharacterized protein.	0.476
CTHT_0003200	CTHT_0054820	G0RZJ7	G0SBU5	AMP deaminase-like protein.	Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.	0.522
CTHT_0003200	CTHT_0057880	G0RZJ7	G0SCN7	AMP deaminase-like protein.	Putative bifunctional purine biosynthesis protein.	0.921
CTHT_0003200	CTHT_0058720	G0RZJ7	G0SCX6	AMP deaminase-like protein.	Pribosyltran domain-containing protein.	0.983
CTHT_0003200	CTHT_0060430	G0RZJ7	G0SF13	AMP deaminase-like protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.971
CTHT_0003200	CTHT_0062440	G0RZJ7	G0SE51	AMP deaminase-like protein.	Amidophosphoribosyltransferase.	0.409
CTHT_0003200	CTHT_0070180	G0RZJ7	G0SHI9	AMP deaminase-like protein.	Putative bifunctional purine biosynthetic protein.	0.424
CTHT_0010500	CTHT_0024020	G0S0M1	G0S543	Formyltetrahydrofolate deformylase-like protein.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.894
CTHT_0010500	CTHT_0026290	G0S0M1	G0S6I0	Formyltetrahydrofolate deformylase-like protein.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.496
CTHT_0010500	CTHT_0031290	G0S0M1	G0S4K1	Formyltetrahydrofolate deformylase-like protein.	Phosphoribosylformylglycinamidine synthase-like protein.	0.955
CTHT_0010500	CTHT_0036600	G0S0M1	G0S7K1	Formyltetrahydrofolate deformylase-like protein.	GMP synthase [glutamine-hydrolyzing]-like protein.	0.459
CTHT_0010500	CTHT_0049640	G0S0M1	G0SBB6	Formyltetrahydrofolate deformylase-like protein.	Uncharacterized protein.	0.496
CTHT_0010500	CTHT_0054820	G0S0M1	G0SBU5	Formyltetrahydrofolate deformylase-like protein.	Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.	0.824
CTHT_0010500	CTHT_0057880	G0S0M1	G0SCN7	Formyltetrahydrofolate deformylase-like protein.	Putative bifunctional purine biosynthesis protein.	0.773
CTHT_0010500	CTHT_0058720	G0S0M1	G0SCX6	Formyltetrahydrofolate deformylase-like protein.	Pribosyltran domain-containing protein.	0.602