19 items (Chaetomium thermophilum) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	CTHT_0032600	Uncharacterized protein. (2253 aa)
	CTHT_0031290	Phosphoribosylformylglycinamidine synthase-like protein. (1355 aa)
	CTHT_0022490	Uncharacterized protein. (1018 aa)
	CTHT_0010500	Formyltetrahydrofolate deformylase-like protein. (285 aa)
	CTHT_0006880	Orotidine 5'-phosphate decarboxylase-like protein. (369 aa)
	CTHT_0069060	Phosphoribosylglycinamide formyltransferase-like protein. (306 aa)
	CTHT_0063240	Dihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. (362 aa)
	CTHT_0070180	Putative bifunctional purine biosynthetic protein. (786 aa)
	CTHT_0064510	Phosphoribosylaminoimidazole-succinocarboxamide synthase-like protein. (302 aa)
	CTHT_0060430	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (543 aa)
	CTHT_0062440	Amidophosphoribosyltransferase. (576 aa)
	CTHT_0057880	Putative bifunctional purine biosynthesis protein. (593 aa)
	CTHT_0054820	Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (614 aa)
	CTHT_0049640	Uncharacterized protein. (108 aa)
	CTHT_0029650	Orotate phosphoribosyltransferase-like protein. (234 aa)
	CTHT_0037330	Putative dihydroorotate protein. (499 aa)
	CTHT_0036600	GMP synthase [glutamine-hydrolyzing]-like protein. (538 aa)
	CTHT_0026290	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (423 aa)
	CTHT_0024020	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (482 aa)

Your Current Organism:

Chaetomium thermophilum

NCBI taxonomy Id: 759272
Other names: C. thermophilum var. thermophilum DSM 1495, Chaetomium thermophilum var. thermophilum DSM 1495

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTHT_0006880	CTHT_0010500	G0RYJ1	G0S0M1	Orotidine 5'-phosphate decarboxylase-like protein.	Formyltetrahydrofolate deformylase-like protein.	0.507
CTHT_0006880	CTHT_0024020	G0RYJ1	G0S543	Orotidine 5'-phosphate decarboxylase-like protein.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.547
CTHT_0006880	CTHT_0029650	G0RYJ1	G0S8F0	Orotidine 5'-phosphate decarboxylase-like protein.	Orotate phosphoribosyltransferase-like protein.	0.962
CTHT_0006880	CTHT_0031290	G0RYJ1	G0S4K1	Orotidine 5'-phosphate decarboxylase-like protein.	Phosphoribosylformylglycinamidine synthase-like protein.	0.498
CTHT_0006880	CTHT_0032600	G0RYJ1	G0S583	Orotidine 5'-phosphate decarboxylase-like protein.	Uncharacterized protein.	0.776
CTHT_0006880	CTHT_0036600	G0RYJ1	G0S7K1	Orotidine 5'-phosphate decarboxylase-like protein.	GMP synthase [glutamine-hydrolyzing]-like protein.	0.538
CTHT_0006880	CTHT_0037330	G0RYJ1	G0S7X5	Orotidine 5'-phosphate decarboxylase-like protein.	Putative dihydroorotate protein.	0.991
CTHT_0006880	CTHT_0054820	G0RYJ1	G0SBU5	Orotidine 5'-phosphate decarboxylase-like protein.	Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.	0.664
CTHT_0006880	CTHT_0057880	G0RYJ1	G0SCN7	Orotidine 5'-phosphate decarboxylase-like protein.	Putative bifunctional purine biosynthesis protein.	0.475
CTHT_0006880	CTHT_0060430	G0RYJ1	G0SF13	Orotidine 5'-phosphate decarboxylase-like protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.456
CTHT_0006880	CTHT_0062440	G0RYJ1	G0SE51	Orotidine 5'-phosphate decarboxylase-like protein.	Amidophosphoribosyltransferase.	0.600
CTHT_0006880	CTHT_0063240	G0RYJ1	G0SEC3	Orotidine 5'-phosphate decarboxylase-like protein.	Dihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.	0.989
CTHT_0006880	CTHT_0064510	G0RYJ1	G0SEP7	Orotidine 5'-phosphate decarboxylase-like protein.	Phosphoribosylaminoimidazole-succinocarboxamide synthase-like protein.	0.629
CTHT_0006880	CTHT_0069060	G0RYJ1	G0SH82	Orotidine 5'-phosphate decarboxylase-like protein.	Phosphoribosylglycinamide formyltransferase-like protein.	0.583
CTHT_0006880	CTHT_0070180	G0RYJ1	G0SHI9	Orotidine 5'-phosphate decarboxylase-like protein.	Putative bifunctional purine biosynthetic protein.	0.640
CTHT_0010500	CTHT_0006880	G0S0M1	G0RYJ1	Formyltetrahydrofolate deformylase-like protein.	Orotidine 5'-phosphate decarboxylase-like protein.	0.507
CTHT_0010500	CTHT_0022490	G0S0M1	G0S4E1	Formyltetrahydrofolate deformylase-like protein.	Uncharacterized protein.	0.439
CTHT_0010500	CTHT_0024020	G0S0M1	G0S543	Formyltetrahydrofolate deformylase-like protein.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.894
CTHT_0010500	CTHT_0026290	G0S0M1	G0S6I0	Formyltetrahydrofolate deformylase-like protein.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.496
CTHT_0010500	CTHT_0029650	G0S0M1	G0S8F0	Formyltetrahydrofolate deformylase-like protein.	Orotate phosphoribosyltransferase-like protein.	0.507