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AKA10277.1 AKA10277.1 AKA10280.1 AKA10280.1 fmt fmt yigZ yigZ trkG_2 trkG_2 hemG hemG mscL mscL aer aer ccmA_1 ccmA_1 ccmB ccmB ccmC ccmC ccmD ccmD ccmE ccmE ccmF_1 ccmF_1 fdhD fdhD AKA10856.1 AKA10856.1 moeA_1 moeA_1 moeB_3 moeB_3 yhaX yhaX AKA11261.1 AKA11261.1 ywnH ywnH ybjQ ybjQ AKA11265.1 AKA11265.1 fnr fnr phoR_2 phoR_2 phoB_1 phoB_1 pstB pstB pstA pstA pstC_3 pstC_3 pstS_1 pstS_1 cpxA_2 cpxA_2 yycF yycF moaE moaE moaD moaD moaC moaC moaA moaA nreC nreC torY_2 torY_2 torZ_1 torZ_1 torZ_4 torZ_4 rebM rebM AKA11484.1 AKA11484.1 yvcK yvcK arcB_3 arcB_3 AKA11791.1 AKA11791.1 mobA mobA AKA11985.1 AKA11985.1 fixJ fixJ fixL fixL AKA12022.1 AKA12022.1 AKA12023.1 AKA12023.1 AKA12024.1 AKA12024.1 AKA12025.1 AKA12025.1 ddhB ddhB AKA12027.1 AKA12027.1 psrA_1 psrA_1 AKA12029.1 AKA12029.1 pcaK pcaK AKA12037.1 AKA12037.1 ratA ratA cysA cysA modB modB modA modA yadH_1 yadH_1 metN_1 metN_1 nrfG_1 nrfG_1 nrfF nrfF dsbE_3 dsbE_3 ccmF_4 ccmF_4 AKA12181.1 AKA12181.1 nrfC nrfC nrfB nrfB nrfA nrfA yhjE yhjE narL_1 narL_1 arcA_2 arcA_2 hemH hemH mobA-2 mobA-2 torD torD torA_4 torA_4 torC_3 torC_3 napC_1 napC_1 AKA12384.1 AKA12384.1 napH napH AKA12386.1 AKA12386.1 napA_5 napA_5 napD napD AKA12389.1 AKA12389.1 dsbE_1 dsbE_1 AKA12561.1 AKA12561.1 ccmH_2 ccmH_2 ccmH_1 ccmH_1 mogA mogA lspA lspA ygfY ygfY torC_1 torC_1 trkA trkA rsmB_2 rsmB_2 AKA12670.1 AKA12670.1 siaT_4 siaT_4 AKA12672.1 AKA12672.1 AKA12674.1 AKA12674.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKA10277.1Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
AKA10280.1Molybdenum ABC transporter ATP-binding protein; Contains 2 ATP-binding cassettes; involved in the transport of molybdenum; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (317 aa)
yigZIMPACT family member; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
trkG_2Potassium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
hemGProtoporphyrinogen oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa)
mscLMechanosensitive ion channel protein MscL; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
aerChemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
ccmA_1Heme ABC transporter ATP-binding protein; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. (213 aa)
ccmBHeme ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (220 aa)
ccmCHeme ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (245 aa)
ccmDCytochrome c maturation protein D; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. (65 aa)
ccmECytochrome C biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (185 aa)
ccmF_1Cytochrome c-type biogenesis protein; required for the transfer of heme to apocytochrome c; Derived by automated computational analysis using gene prediction method: Protein Homology. (652 aa)
fdhDFormate dehydrogenase; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (270 aa)
AKA10856.1Autotransporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
moeA_1Molybdopterin molybdenumtransferase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (409 aa)
moeB_3Molybdopterin-synthase adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
yhaXHAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
AKA11261.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa)
ywnHSortase; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
ybjQHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa)
AKA11265.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
fnrTranscriptional regulator; Global transcription factor that controls the expression of over 100 target genes in response to anoxia; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
phoR_2ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
phoB_1Transcriptional regulator PhoB; Two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
pstBPhosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (256 aa)
pstAHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
pstC_3Phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
pstS_1Phosphate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
cpxA_2Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
yycFResponse regulator in two-component regulatory system with CpxA; part of the envelope stress response system; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
moaEMolybdopterin guanine dinucleotide biosynthesis protein MoaE; Catalyzes the conversion of molybdopterin precursor Z into molybdopterin; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)
moaDMolybdopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (81 aa)
moaCMolybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (158 aa)
moaAMolybdenum cofactor biosynthesis protein A; Together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
nreCAmino acid ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa)
torY_2Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
torZ_1Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (828 aa)
torZ_4Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (785 aa)
rebMHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
AKA11484.1Permase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
yvcKHypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (312 aa)
arcB_3Aerobic respiration control protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (616 aa)
AKA11791.1Thiamine biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
mobABifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobA/MobB; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (343 aa)
AKA11985.1Phosphoprotein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
fixJTetrathionate response regulatory protein TtrR; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
fixLTetrathionate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (552 aa)
AKA12022.1Pilus assembly protein CpaF; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
AKA12023.1Hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. (98 aa)
AKA12024.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
AKA12025.1Phosphoribosylglycinamide formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (74 aa)
ddhBTetrathionate reductase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
AKA12027.1Tetrathionate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
psrA_1Tetrathionate reductase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. (1031 aa)
AKA12029.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
pcaKMFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
AKA12037.1Protein RnfH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0125 (RnfH) family. (111 aa)
ratAHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
cysAMolybdenum ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
modBPart of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
modAMolybdate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
yadH_1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
metN_1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
nrfG_1Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
nrfFCytochrome C biosynthesis protein; Possible subunit of a heme lyase. (150 aa)
dsbE_3Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
ccmF_4Cytochrome C biogenesis protein CcmF; Derived by automated computational analysis using gene prediction method: Protein Homology. (634 aa)
AKA12181.1Nitrite reductase; Membrane protein, may be involved in the transfer of electrons from quinones to c-type cytochromes; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
nrfCNitrite reductase; 4Fe4S subunit; may be involved in the transfer of electrons from quinones to the c-type cytochromes; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
nrfBCysteine dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
nrfACytochrome C nitrite reductase; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family. (500 aa)
yhjETransporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
narL_1Nitrate/nitrite response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
arcA_2TorR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (320 aa)
mobA-2Bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobA/MobB; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (369 aa)
torDMolecular chaperone TorD; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
torA_4Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (821 aa)
torC_3Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
napC_1Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
AKA12384.1Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
napHPart of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
AKA12386.1Quinol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
napA_5Nitrate reductase; Periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; Derived by automated computational analysis using gene prediction method: Protein Homology. (832 aa)
napDReductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa)
AKA12389.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
dsbE_1Thiol:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
AKA12561.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
ccmH_2Cystathionine gamma-synthase; Possible subunit of a heme lyase. (161 aa)
ccmH_1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
mogAMolybdenum cofactor biosynthesis protein MogA; Forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
lspALipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (159 aa)
ygfYHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (82 aa)
torC_1Pentahemic C cytochrome; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
trkAInvolved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
rsmB_216S rRNA methyltransferase; Catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (443 aa)
AKA12670.1Universal stress protein UspA; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
siaT_4C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (882 aa)
AKA12672.1C4-dicarboxylate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
AKA12674.1Plasmid stabilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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