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| | mutS_1 | DNA mismatch repair protein MutS; This protein performs the mismatch recognition step during the DNA repair process; Derived by automated computational analysis using gene prediction method: Protein Homology. (865 aa) |
| | smf | DNA repair protein Smf; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa) |
| | hda | DNA replication protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family. (236 aa) |
| | holB | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa) |
| | mutL | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (627 aa) |
| | mutM | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (274 aa) |
| | AKA10486.1 | Competence protein ComF; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa) |
| | AKA10538.1 | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa) |
| | AKA10540.1 | Opacity-associated protein B; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa) |
| | holD | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. (140 aa) |
| | holC | DNA polymerase III subunit chi; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa) |
| | recN_2 | Recombination and repair protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa) |
| | dnaN | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (367 aa) |
| | dnaA | Chromosomal replication initiation protein; Binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa) |
| | uvrD | DNA-dependent helicase II; Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Derived by automated computational analysis using gene prediction method: Protein Homology. (732 aa) |
| | rimN | tRNA threonylcarbamoyladenosine biosynthesis protein RimN; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. (184 aa) |
| | topA_2 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa) |
| | AKA10706.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0267 family. (103 aa) |
| | recX | Recombinase RecX; Modulates RecA activity; Belongs to the RecX family. (158 aa) |
| | recA | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (368 aa) |
| | rmuC_2 | Recombinase RmuC; Derived by automated computational analysis using gene prediction method: Protein Homology. (539 aa) |
| | prfA | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (360 aa) |
| | AKA10713.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa) |
| | prmC | SAM-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (288 aa) |
| | AKA10715.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa) |
| | rep | ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (672 aa) |
| | ligA | NAD-dependent DNA ligase LigA; This protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; Derived by automated computational analysis using gene prediction method: Protein Homology. (685 aa) |
| | recF | Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (361 aa) |
| | ybaB | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (109 aa) |
| | recR | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (201 aa) |
| | AKA10819.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa) |
| | yabJ | Aminoacrylate peracid reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa) |
| | ruvB | ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (334 aa) |
| | ruvA | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (201 aa) |
| | dnaE | DNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1158 aa) |
| | AKA10985.1 | Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa) |
| | AKA11134.1 | DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa) |
| | polA_3 | DNA polymerase I; Has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; Derived by automated computational analysis using gene prediction method: Protein Homology. (952 aa) |
| | recJ_1 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa) |
| | AKA11396.1 | Recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (760 aa) |
| | topA_1 | DNA topoisomerase I; Catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; Derived by automated computational analysis using gene prediction method: Protein Homology. (868 aa) |
| | uvrB_2 | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; Derived by automated computational analysis using gene prediction method: Protein Homology. (672 aa) |
| | dnaB_3 | DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (487 aa) |
| | AKA11592.1 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (641 aa) |
| | uvrA_1 | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (942 aa) |
| | topB_5 | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (683 aa) |
| | dnaB_1 | DNA helicase; Unwinds double stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa) |
| | rnhA_2 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (153 aa) |
| | holA | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa) |
| | yacG | DNA gyrase inhibitor; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. (61 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (211 aa) |
| | AKA11761.1 | Peptidase A24; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa) |
| | AKA11762.1 | Fimbrial protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa) |
| | AKA11763.1 | Pilus assembly protein PilB; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa) |
| | ppdD | Prepilin peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (459 aa) |
| | rapA_4 | ATP-dependent helicase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (970 aa) |
| | recQ | ATP-dependent DNA helicase RecQ; Functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (599 aa) |
| | uvrC | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (612 aa) |
| | lexA | LexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (211 aa) |
| | dnaX_1 | DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (685 aa) |
| | dnaQ | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa) |
| | dinB_2 | DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA polymerase type-Y family. (360 aa) |
| | ruvC | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (192 aa) |
| | mfd_2 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1177 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (582 aa) |
| | AKA12399.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa) |
| | AKA12490.1 | Adenine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1000 aa) |
| | helD_1 | Derived by automated computational analysis using gene prediction method: Protein Homology. (926 aa) |
| | AKA12492.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (603 aa) |
