STRINGSTRING
fadE fadE fadB fadB fadA fadA c1A56 c1A56 c2A172 c2A172 c2A173 c2A173 c2A174 c2A174 c2A178 c2A178 acsA acsA ech ech accB accB accC accC acsA-2 acsA-2 ebA1829 ebA1829 ebA1953 ebA1953 badI badI badH badH badR badR badJ badJ aliA aliA badK badK aidB aidB ebA2038 ebA2038 ebA2049 ebA2049 ebA2194 ebA2194 dhaL dhaL pta pta ackA ackA ebA2313 ebA2313 ebA2314 ebA2314 ebA2315 ebA2315 tioL tioL xccC xccC acsA-3 acsA-3 ebA3433 ebA3433 paaG paaG paaH paaH ebA3639 ebA3639 ebA3640 ebA3640 ebA3642 ebA3642 ebA3654 ebA3654 ebA3691 ebA3691 pccB pccB pccA pccA accA accA ebA4327 ebA4327 acd acd ebA4657 ebA4657 ebA4659 ebA4659 hmgL hmgL ebA4666 ebA4666 ebA4717 ebA4717 kctA kctA kctB kctB hbdA hbdA accD accD ackA-2 ackA-2 ebA5202 ebA5202 bzdZ bzdZ ebA5316 ebA5316 ebA5317 ebA5317 ebA5318 ebA5318 ebA5319 ebA5319 ebA5320 ebA5320 ebA5321 ebA5321 fabH fabH fabD fabD fabG fabG fabF fabF ferA ferA ebA5619 ebA5619 ebA5620 ebA5620 ebA5641 ebA5641 ferA-2 ferA-2 ebA5668 ebA5668 pimD pimD ebA5670 ebA5670 ebA5671 ebA5671 ebA5673 ebA5673 ebA5677 ebA5677 paaJ paaJ paaF paaF ebA5760 ebA5760 xccB xccB xccC-2 xccC-2 ebA5797 ebA5797 fadH fadH ebA6155 ebA6155 ebA6190 ebA6190 ebA6506 ebA6506 etfA etfA etfB etfB fabI fabI ebA720 ebA720 prpE prpE ebA7223 ebA7223 ebA723 ebA723 ebA736 ebA736 ebB200 ebB200 xccB-2 xccB-2 acpP acpP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fadELong chain acyl-CoA dehydrogenase. (829 aa)
fadBAlpha-subunit of fatty acid oxidation complex. (678 aa)
fadABeta-subunit of fatty acid oxidation complex, 3-keto-acyl-CoA-thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (426 aa)
c1A56Hypothetical protein, possible electron transfer protein:ubiquinone oxidoreductase (fragment); Accepts electrons from ETF and reduces ubiquinone. (104 aa)
c2A172beta-Ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
c2A1733-Hydroxyacyl-CoA dehydrogenase. (506 aa)
c2A174Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa)
c2A178Electron transfer flavoprotein:ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (550 aa)
acsAPutative acetyl-coenzyme A synthetase. (563 aa)
echPutative enoyl-CoA hydratase protein; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
accBAcetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (150 aa)
accCPutative biotin carboxylase protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (454 aa)
acsA-2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (662 aa)
ebA1829Conserved hypothetical protein,predicted malonyl-CoA decarboxylase family. (459 aa)
ebA1953Acyl-CoA dehydrogenase. (384 aa)
badI2-ketocyclohexanecarboxyl-CoA hydrolase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (260 aa)
badHPutative 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase. (255 aa)
badRTranscriptional regulator, protein,possibly involved in regulating genes for cyclohexanecarboxylate metabolism. (167 aa)
badJCyclohexanecarboxyl-CoA dehydrogenase. (382 aa)
aliACyclohexanecarboxylate-CoA ligase. (549 aa)
badKCyclohex-1-ene-1-carboxyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
aidBAcyl-CoA dehydrogenase. (542 aa)
ebA2038Fusion of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase. (671 aa)
ebA2049Putative beta-oxoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
ebA2194Predicted Acetyl-CoA synthetase. (727 aa)
dhaLAldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa)
ptaPutative phosphate acetyltransferase (EC 2.3.1.8), gene: PTA OR RPA4567. (470 aa)
ackAPutative acetate kinase (EC 2.7.2.1),gene: ACKA OR RPA4566; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa)
ebA2313Putative enoyl-CoA hydratase II. (266 aa)
ebA2314Putative thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
ebA2315Fusion of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase. (797 aa)
tioLPredicted thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
xccCBiotin carboxylase subunit of acetyl-CoA carboxylase-like enzyme. (460 aa)
acsA-3Acetoacetyl-CoA synthetase. (664 aa)
ebA3433Putative AMP-binding enzyme. (546 aa)
paaGPutative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (272 aa)
paaH3-Hydroxyacyl-CoA dehydrogenase PaaH involved in aerobic phenylacetate metabolism. (509 aa)
ebA3639Putative acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
ebA3640Putative acyl CoA dehydrogenase oxidoreductase protein. (377 aa)
ebA3642Putative enoyl-CoA hydratase protein; Belongs to the enoyl-CoA hydratase/isomerase family. (263 aa)
ebA3654Alcohol dehydrogenase. (327 aa)
ebA3691Predicted Enoyl-CoA hydratase/carnithine racemase. (260 aa)
pccBPropionyl-CoA carboxylase beta subunit. (510 aa)
pccAPropionyl-CoA carboxylase, alpha subunit. (666 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (380 aa)
ebA4327Acyl-CoA dehydrogenase. (382 aa)
acdAcyl-CoA dehydrogenase, probably isovaleryl-CoA dehydrogenase. (397 aa)
ebA4657Putative propionyl-CoA carboxylase (Beta subunit). (535 aa)
ebA4659Putative acyl-CoA carboxylase alpha chain protein. (667 aa)
hmgL3-hydroxymethylglutaryl-CoA or malyl-CoA lyase. (303 aa)
ebA4666Putative acetoacetyl-CoA synthetase. (662 aa)
ebA4717Acyl-CoA synthetase. (663 aa)
kctASuccinyl-CoA:3-ketoacid-coenzyme A transferase subunit A. (232 aa)
kctBSuccinyl-CoA:3-ketoacid-coenzyme A transferase subunit B. (215 aa)
hbdA3-hydroxybutyryl-CoA dehydrogenase. (283 aa)
accDPutative acetyl-coenzyme A carboxylase carboxyl transferase (Subunit beta) protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa)
ackA-2Similar to acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (774 aa)
ebA5202Putative thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
bzdZPutative dehydrogenase. (248 aa)
ebA5316Putative ABC transporter,periplasmic binding protein. (380 aa)
ebA5317Long-chain-fatty-acid-CoA ligase (EC 6.2.1.3). (624 aa)
ebA5318Putative enoyl-coa hydratase/isomerase. (256 aa)
ebA5319Putative beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family. (421 aa)
ebA5320Putative 3-hydroxyacyl-CoA dehydrogenase precursor; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (255 aa)
ebA5321Probable acyl-CoA dehydrogenase. (599 aa)
fabH3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (321 aa)
fabDProbable malonyl CoA-[acyl-carrier-protein] transacylase. (309 aa)
fabGShort-chain dehydrogenase/reductase (SDR) superfamily; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (252 aa)
fabFBeta-ketoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)
ferAOrganic acid-CoA ligase (ADP forming),similar to feruloyl-CoA synthetase. (712 aa)
ebA5619Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (266 aa)
ebA56203-hydroxyacyl-CoA dehydrogenase. (443 aa)
ebA5641Acyl-CoA dehydrogenase. (382 aa)
ferA-2Organic acid-CoA ligase (ADP forming) similar to feruloyl-CoA synthetase. (716 aa)
ebA5668Putative acyl-CoA dehydrogenase oxidoreductase protein. (398 aa)
pimDPutative pimeloyl-CoA dehydrogenase (EC 1.3.1.62). (379 aa)
ebA5670Putative dehydrogenase (Short chain alcohol dehydrogenase). (304 aa)
ebA5671Predicted MaoC-like (R)-specific enoyl-CoA hydratase. (286 aa)
ebA5673Predicted Acetyl-CoA acetyltransferase (thiolase). (387 aa)
ebA5677Putative transporter. (523 aa)
paaJPutative 3-ketoadipyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
paaFPutative enoyl-CoA hydratase protein. (267 aa)
ebA5760CoA ligase (AMP forming), possibly acetoacetyl-CoA synthetase. (664 aa)
xccBBiotin carboxyl carrier subunit of acetyl-CoA carboxylase-like protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (162 aa)
xccC-2Biotin carboxylase subunit of unknown acetyl-CoA carboxylase-like enzyme. (451 aa)
ebA5797Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
fadH2,4-dienoyl-CoA reductase. (686 aa)
ebA6155Putative electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (547 aa)
ebA6190Putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (501 aa)
ebA6506Acyl-CoA dehydrogenase. (597 aa)
etfAElectron transfer flavoprotein alpha subunit. (320 aa)
etfBElectron transfer flavoprotein, beta-subunit. (249 aa)
fabIEnoyl-[acyl-carrier-protein] reductase. (263 aa)
ebA720Enoyl-CoA hydratase. (253 aa)
prpEPropionate-CoA ligase. (630 aa)
ebA7223Predicted Zinc-containing alcohol dehydrogenase. (332 aa)
ebA723Putative alcohol dehydrogenase. (248 aa)
ebA736Putative acyl-CoA dehydrogenase. (392 aa)
ebB200Conserved hypothetical protein,probable small subunit of thiolase encoded by ebA5673. (130 aa)
xccB-2Biotin carboxyl carrier protein of unknown carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (163 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (79 aa)
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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