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accB accB accC accC xccC xccC accA accA ebA4749 ebA4749 accD accD bzdZ bzdZ fabH fabH fabD fabD fabG fabG fabF fabF xccB xccB xccC-2 xccC-2 ped2 ped2 fabZ fabZ ebA6242 ebA6242 fabI fabI fabF1 fabF1 fabG1 fabG1 xccB-2 xccB-2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
accBAcetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (150 aa)
accCPutative biotin carboxylase protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (454 aa)
xccCBiotin carboxylase subunit of acetyl-CoA carboxylase-like enzyme. (460 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (380 aa)
ebA4749Long chain fatty-acid CoA ligase. (555 aa)
accDPutative acetyl-coenzyme A carboxylase carboxyl transferase (Subunit beta) protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa)
bzdZPutative dehydrogenase. (248 aa)
fabH3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (321 aa)
fabDProbable malonyl CoA-[acyl-carrier-protein] transacylase. (309 aa)
fabGShort-chain dehydrogenase/reductase (SDR) superfamily; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (252 aa)
fabFBeta-ketoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)
xccBBiotin carboxyl carrier subunit of acetyl-CoA carboxylase-like protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (162 aa)
xccC-2Biotin carboxylase subunit of unknown acetyl-CoA carboxylase-like enzyme. (451 aa)
ped2(S)-1-Phenylethanol dehydrogenase. (249 aa)
fabZ(3R)-hydroxyacyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (145 aa)
ebA6242Putative long-chain-fatty-acid-CoA ligase. (488 aa)
fabIEnoyl-[acyl-carrier-protein] reductase. (263 aa)
fabF1Probable 3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (395 aa)
fabG13-oxoacyl-[ACP] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (239 aa)
xccB-2Biotin carboxyl carrier protein of unknown carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (163 aa)
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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