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fadB fadB fadA fadA c2A172 c2A172 acsA acsA sucD sucD sucC sucC ech ech lpd lpd accB accB accC accC acsA-2 acsA-2 ebA1829 ebA1829 sbmA sbmA ebA2194 ebA2194 pta pta ackA ackA xccC xccC ebA3639 ebA3639 ebA3640 ebA3640 ebA3654 ebA3654 sbmB sbmB pccB pccB pccA pccA accA accA ebA4717 ebA4717 accD accD ackA-2 ackA-2 ebA5202 ebA5202 acnB acnB ebA5319 ebA5319 ferA ferA ferA-2 ferA-2 ebA5673 ebA5673 paaF paaF xccB xccB xccC-2 xccC-2 ldp ldp prpE prpE ebA7223 ebA7223 xccB-2 xccB-2 SbmB SbmB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fadBAlpha-subunit of fatty acid oxidation complex. (678 aa)
fadABeta-subunit of fatty acid oxidation complex, 3-keto-acyl-CoA-thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (426 aa)
c2A172beta-Ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
acsAPutative acetyl-coenzyme A synthetase. (563 aa)
sucDSuccinyl-CoA synthetase, alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (297 aa)
sucCSuccinyl-CoA synthetase, beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
echPutative enoyl-CoA hydratase protein; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
lpdPyruvate dehydrogenase multienzyme complex, Dihydrolipoamide dehydrogenase component. (615 aa)
accBAcetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (150 aa)
accCPutative biotin carboxylase protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (454 aa)
acsA-2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (662 aa)
ebA1829Conserved hypothetical protein,predicted malonyl-CoA decarboxylase family. (459 aa)
sbmAMethylmalonyl-CoA mutase subunit alpha. (537 aa)
ebA2194Predicted Acetyl-CoA synthetase. (727 aa)
ptaPutative phosphate acetyltransferase (EC 2.3.1.8), gene: PTA OR RPA4567. (470 aa)
ackAPutative acetate kinase (EC 2.7.2.1),gene: ACKA OR RPA4566; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa)
xccCBiotin carboxylase subunit of acetyl-CoA carboxylase-like enzyme. (460 aa)
ebA3639Putative acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
ebA3640Putative acyl CoA dehydrogenase oxidoreductase protein. (377 aa)
ebA3654Alcohol dehydrogenase. (327 aa)
sbmBMethylmalonyl-CoA mutase, beta subunit. (722 aa)
pccBPropionyl-CoA carboxylase beta subunit. (510 aa)
pccAPropionyl-CoA carboxylase, alpha subunit. (666 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (380 aa)
ebA4717Acyl-CoA synthetase. (663 aa)
accDPutative acetyl-coenzyme A carboxylase carboxyl transferase (Subunit beta) protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa)
ackA-2Similar to acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (774 aa)
ebA5202Putative thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
acnBAconitase; Belongs to the aconitase/IPM isomerase family. (869 aa)
ebA5319Putative beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family. (421 aa)
ferAOrganic acid-CoA ligase (ADP forming),similar to feruloyl-CoA synthetase. (712 aa)
ferA-2Organic acid-CoA ligase (ADP forming) similar to feruloyl-CoA synthetase. (716 aa)
ebA5673Predicted Acetyl-CoA acetyltransferase (thiolase). (387 aa)
paaFPutative enoyl-CoA hydratase protein. (267 aa)
xccBBiotin carboxyl carrier subunit of acetyl-CoA carboxylase-like protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (162 aa)
xccC-2Biotin carboxylase subunit of unknown acetyl-CoA carboxylase-like enzyme. (451 aa)
ldp2-oxoglutarate dehydrogenase complex, E3 component, Dihydrolipoamide dehydrogenase. (476 aa)
prpEPropionate-CoA ligase. (630 aa)
ebA7223Predicted Zinc-containing alcohol dehydrogenase. (332 aa)
xccB-2Biotin carboxyl carrier protein of unknown carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (163 aa)
SbmBMethylmalonyl-CoA mutase, C-terminal domain/subunit (Cobalamin-binding). (139 aa)
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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