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fadE fadE fadB fadB fadA fadA c2A172 c2A172 ech ech accB accB accC accC ebA2049 ebA2049 ebA2314 ebA2314 ebA2315 ebA2315 tioL tioL xccC xccC ebA3639 ebA3639 ebA3640 ebA3640 accA accA ebA4749 ebA4749 accD accD ebA5202 ebA5202 bzdZ bzdZ ebA5319 ebA5319 fabH fabH fabD fabD fabG fabG fabF fabF ebA5620 ebA5620 ebA5641 ebA5641 ebA5673 ebA5673 paaF paaF xccB xccB xccC-2 xccC-2 ped2 ped2 ebA5797 ebA5797 fabZ fabZ ebA6242 ebA6242 ebA644 ebA644 fabI fabI fabF1 fabF1 fabG1 fabG1 ebA736 ebA736 xccB-2 xccB-2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fadELong chain acyl-CoA dehydrogenase. (829 aa)
fadBAlpha-subunit of fatty acid oxidation complex. (678 aa)
fadABeta-subunit of fatty acid oxidation complex, 3-keto-acyl-CoA-thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (426 aa)
c2A172beta-Ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
echPutative enoyl-CoA hydratase protein; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
accBAcetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (150 aa)
accCPutative biotin carboxylase protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (454 aa)
ebA2049Putative beta-oxoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
ebA2314Putative thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
ebA2315Fusion of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase. (797 aa)
tioLPredicted thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
xccCBiotin carboxylase subunit of acetyl-CoA carboxylase-like enzyme. (460 aa)
ebA3639Putative acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
ebA3640Putative acyl CoA dehydrogenase oxidoreductase protein. (377 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (380 aa)
ebA4749Long chain fatty-acid CoA ligase. (555 aa)
accDPutative acetyl-coenzyme A carboxylase carboxyl transferase (Subunit beta) protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa)
ebA5202Putative thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
bzdZPutative dehydrogenase. (248 aa)
ebA5319Putative beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family. (421 aa)
fabH3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (321 aa)
fabDProbable malonyl CoA-[acyl-carrier-protein] transacylase. (309 aa)
fabGShort-chain dehydrogenase/reductase (SDR) superfamily; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (252 aa)
fabFBeta-ketoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)
ebA56203-hydroxyacyl-CoA dehydrogenase. (443 aa)
ebA5641Acyl-CoA dehydrogenase. (382 aa)
ebA5673Predicted Acetyl-CoA acetyltransferase (thiolase). (387 aa)
paaFPutative enoyl-CoA hydratase protein. (267 aa)
xccBBiotin carboxyl carrier subunit of acetyl-CoA carboxylase-like protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (162 aa)
xccC-2Biotin carboxylase subunit of unknown acetyl-CoA carboxylase-like enzyme. (451 aa)
ped2(S)-1-Phenylethanol dehydrogenase. (249 aa)
ebA5797Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
fabZ(3R)-hydroxyacyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (145 aa)
ebA6242Putative long-chain-fatty-acid-CoA ligase. (488 aa)
ebA644Fatty acid desaturase, type 2. (389 aa)
fabIEnoyl-[acyl-carrier-protein] reductase. (263 aa)
fabF1Probable 3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (395 aa)
fabG13-oxoacyl-[ACP] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (239 aa)
ebA736Putative acyl-CoA dehydrogenase. (392 aa)
xccB-2Biotin carboxyl carrier protein of unknown carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (163 aa)
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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