STRINGSTRING
ALO47691.1 ALO47691.1 ALO47717.1 ALO47717.1 ALO47718.1 ALO47718.1 ackA ackA ALO47736.1 ALO47736.1 ALO47737.1 ALO47737.1 ALO47956.1 ALO47956.1 ALO49788.1 ALO49788.1 ALO47957.1 ALO47957.1 ALO48061.1 ALO48061.1 ALO48074.1 ALO48074.1 nagB nagB ALO48124.1 ALO48124.1 ALO48299.1 ALO48299.1 ALO48305.1 ALO48305.1 ALO48310.1 ALO48310.1 ALO48337.1 ALO48337.1 ALO48393.1 ALO48393.1 pfkA pfkA pfp pfp eno eno ALO48774.1 ALO48774.1 pgi pgi ALO49001.1 ALO49001.1 pgk pgk pdxS pdxS pdxT pdxT ALO49172.1 ALO49172.1 ALO49190.1 ALO49190.1 tpiA tpiA ALO49233.1 ALO49233.1 ALO49234.1 ALO49234.1 ALO49954.1 ALO49954.1 ALO49955.1 ALO49955.1 ALO49299.1 ALO49299.1 ALO49300.1 ALO49300.1 ALO49340.1 ALO49340.1 ALO49386.1 ALO49386.1 ALO49417.1 ALO49417.1 pflA pflA gpmI gpmI ALO49444.1 ALO49444.1 ALO49445.1 ALO49445.1 ALO49446.1 ALO49446.1 ALO49447.1 ALO49447.1 ALO49448.1 ALO49448.1 pckA pckA gpmA gpmA ALO49604.1 ALO49604.1 ALO49703.1 ALO49703.1 ALO49707.1 ALO49707.1 sdhA sdhA ALO49709.1 ALO49709.1 sucD sucD sucC sucC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALO47691.1Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
ALO47717.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa)
ALO47718.1Phosphotransacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa)
ALO47736.12-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
ALO47737.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (616 aa)
ALO47956.1Porin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family. (228 aa)
ALO49788.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
ALO47957.1Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
ALO48061.1Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (339 aa)
ALO48074.1Pyruvate phosphate dikinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. (905 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (264 aa)
ALO48124.1Glucosamine-6-phosphate deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (663 aa)
ALO48299.1Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
ALO48305.1Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
ALO48310.1Ribose-phosphate pyrophosphokinase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
ALO48337.1Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
ALO48393.1Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1188 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa)
pfpDiphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (546 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (435 aa)
ALO48774.1Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (549 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (449 aa)
ALO49001.1Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (582 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (416 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (291 aa)
pdxTGlutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (189 aa)
ALO49172.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (482 aa)
ALO49190.1Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (496 aa)
ALO49233.1Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
ALO49234.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. (672 aa)
ALO49954.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (77 aa)
ALO49955.12-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
ALO49299.12-oxoglutarate oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
ALO49300.12-oxoglutarate ferredoxin oxidoreductase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
ALO49340.1Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (764 aa)
ALO49386.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. (330 aa)
ALO49417.1Formate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (748 aa)
pflAPyruvate formate lyase-activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (279 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (506 aa)
ALO49444.1ROK family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
ALO49445.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
ALO49446.1Glucosamine--fructose-6-phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
ALO49447.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
ALO49448.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (537 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (230 aa)
ALO49604.12-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
ALO49703.12-deoxyribose-5-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (313 aa)
ALO49707.1Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (648 aa)
ALO49709.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (289 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (379 aa)
Your Current Organism:
Prevotella enoeca
NCBI taxonomy Id: 76123
Other names: ATCC 51261, CIP 104472, JCM 12259, NCTC 13068, P. enoeca, VPI D194A-25A
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.