(22 nodes) Innate Immune System network (Prevotella enoeca)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	apt	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (176 aa)
	ALO49748.1	Alpha-1,3/4-fucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (724 aa)
	ALO47738.1	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
	ALO47739.1	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
	ALO47740.1	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
	ALO49804.1	4-alpha-glucanotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (637 aa)
	ALO48125.1	Beta-glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family. (1177 aa)
	ALO48378.1	Patatin; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
	ALO48416.1	alpha-L-fucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
	ALO48766.1	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (159 aa)
	ALO49725.1	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (406 aa)
	ALO48778.1	serine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
	pgi	Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (449 aa)
	ALO48969.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
	xpt	Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (188 aa)
	ALO49357.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
	ALO49972.1	Beta-mannosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family. (913 aa)
	ALO49986.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (536 aa)
	ALO49516.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BI1 family. (237 aa)
	ALO49591.1	Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1052 aa)
	ALO49681.1	Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family. (807 aa)
	ALO49703.1	2-deoxyribose-5-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (313 aa)

Your Current Organism:

Prevotella enoeca

NCBI taxonomy Id: 76123
Other names: ATCC 51261, CIP 104472, JCM 12259, NCTC 13068, P. enoeca, VPI D194A-25A

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALO47738.1	ALO47739.1	AS203_00310	AS203_00315	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.852
ALO47738.1	ALO47740.1	AS203_00310	AS203_00320	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.655
ALO47739.1	ALO47738.1	AS203_00315	AS203_00310	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.852
ALO47739.1	ALO47740.1	AS203_00315	AS203_00320	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.668
ALO47740.1	ALO47738.1	AS203_00320	AS203_00310	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.655
ALO47740.1	ALO47739.1	AS203_00320	AS203_00315	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.668
ALO48125.1	ALO48416.1	AS203_02665	AS203_04400	Beta-glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family.	alpha-L-fucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.400
ALO48125.1	ALO49591.1	AS203_02665	AS203_11260	Beta-glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family.	Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.585
ALO48125.1	ALO49681.1	AS203_02665	AS203_11800	Beta-glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family.	Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family.	0.506
ALO48125.1	ALO49748.1	AS203_02665	AS203_00035	Beta-glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family.	Alpha-1,3/4-fucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.586
ALO48416.1	ALO48125.1	AS203_04400	AS203_02665	alpha-L-fucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Beta-glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family.	0.400
ALO48416.1	ALO49748.1	AS203_04400	AS203_00035	alpha-L-fucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alpha-1,3/4-fucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.934
ALO48416.1	ALO49972.1	AS203_04400	AS203_10345	alpha-L-fucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Beta-mannosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family.	0.577
ALO48766.1	ALO49703.1	AS203_06480	AS203_11915	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	2-deoxyribose-5-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.	0.730
ALO48969.1	ALO49748.1	AS203_07660	AS203_00035	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alpha-1,3/4-fucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.450
ALO49591.1	ALO48125.1	AS203_11260	AS203_02665	Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Beta-glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family.	0.585
ALO49591.1	ALO49681.1	AS203_11260	AS203_11800	Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family.	0.929
ALO49591.1	ALO49748.1	AS203_11260	AS203_00035	Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alpha-1,3/4-fucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.553
ALO49681.1	ALO48125.1	AS203_11800	AS203_02665	Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family.	Beta-glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family.	0.506
ALO49681.1	ALO49591.1	AS203_11800	AS203_11260	Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family.	Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.929