(93 nodes) Mixed, incl. Nucleotide catabolism, and Polyamine metabolic process network (Papilio machaon)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RR48_02495	Trifunctional nucleotide phosphoesterase protein YfkN. (505 aa)
	RR48_03584	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (184 aa)
	RR48_05658	Xanthine dehydrogenase. (2671 aa)
	RR48_02375	Metal transporter CNNM2. (194 aa)
	RR48_01922	Double-stranded RNA-specific editase Adar. (285 aa)
	RR48_05530	Uncharacterized protein. (517 aa)
	RR48_02348	Uridine kinase; Belongs to the uridine kinase family. (695 aa)
	RR48_05656	Xanthine dehydrogenase. (1385 aa)
	RR48_03640	Uncharacterized protein. (385 aa)
	RR48_03641	Uncharacterized protein. (598 aa)
	RR48_03519	Putative deoxyhypusine synthase. (370 aa)
	RR48_01979	RRN7-type domain-containing protein. (126 aa)
	RR48_05955	Acidic repeat-containing protein. (814 aa)
	RR48_01794	Histidine triad nucleotide-binding protein 3. (192 aa)
	RR48_01473	Aldehyde oxidase 2. (1244 aa)
	RR48_02038	5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (113 aa)
	RR48_00448	Spermine oxidase. (206 aa)
	RR48_05716	Single-strand selective monofunctional uracil DNA glycosylase. (273 aa)
	RR48_03085	Xanthine dehydrogenase/oxidase. (1417 aa)
	RR48_04284	Spermidine synthase; Belongs to the spermidine/spermine synthase family. (403 aa)
	RR48_04278	Adenosine deaminase CECR1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (467 aa)
	RR48_03857	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. (171 aa)
	RR48_05657	Xanthine dehydrogenase. (1286 aa)
	RR48_00853	Apyrase; Belongs to the 5'-nucleotidase family. (349 aa)
	RR48_05846	Diamine acetyltransferase 2. (171 aa)
	RR48_01978	Uncharacterized protein. (677 aa)
	RR48_05856	Diamine acetyltransferase 2. (146 aa)
	RR48_03583	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (184 aa)
	RR48_02354	Metal transporter CNNM2. (765 aa)
	RR48_00389	Xanthine dehydrogenase. (83 aa)
	RR48_00566	5'-nucleotidase. (166 aa)
	RR48_02814	Uridine phosphorylase 1. (334 aa)
	RR48_00265	Uncharacterized protein. (72 aa)
	RR48_02039	5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (113 aa)
	RR48_00345	Uncharacterized protein. (78 aa)
	RR48_04845	Protein 5NUC. (1748 aa)
	RR48_02838	Adenine phosphoribosyltransferase. (183 aa)
	RR48_03759	Probable methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (223 aa)
	RR48_05847	Diamine acetyltransferase 2. (176 aa)
	RR48_01849	Abscisic-aldehyde oxidase. (188 aa)
	RR48_03130	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (302 aa)
	RR48_00962	S-adenosylmethionine decarboxylase proenzyme. (202 aa)
	RR48_04130	Protein tyrosine phosphatase type IVA 3. (154 aa)
	RR48_02374	Metal transporter CNNM2. (735 aa)
	RR48_14436	Allantoicase. (371 aa)
	RR48_14362	Xanthine dehydrogenase. (1236 aa)
	RR48_14353	Aldehyde oxidase 2. (1212 aa)
	RR48_12984	Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (345 aa)
	RR48_07562	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (324 aa)
	RR48_12373	Abscisic-aldehyde oxidase. (2218 aa)
	RR48_08894	Deoxynucleoside kinase. (247 aa)
	RR48_15221	Uncharacterized protein. (555 aa)
	RR48_06341	Adenosine deaminase-like protein. (168 aa)
	RR48_07819	D-tyrosyl-tRNA(Tyr) deacylase 1. (90 aa)
	RR48_10038	Protein quiver. (141 aa)
	RR48_09010	Rhythmically expressed gene 2 protein. (248 aa)
	RR48_10217	tRNA-specific adenosine deaminase-like protein 3. (373 aa)
	RR48_14812	Xanthine dehydrogenase. (1000 aa)
	RR48_14751	Uridine phosphorylase 1. (336 aa)
	RR48_14813	Xanthine dehydrogenase. (317 aa)
	RR48_08320	Apyrase; Belongs to the 5'-nucleotidase family. (461 aa)
	RR48_08340	Adenosine deaminase CECR1. (480 aa)
	RR48_08284	5'-nucleotidase; Belongs to the 5'-nucleotidase family. (539 aa)
	RR48_08339	Adenosine deaminase CECR1. (505 aa)
	RR48_14814	Xanthine dehydrogenase. (1345 aa)
	RR48_08321	Apyrase; Belongs to the 5'-nucleotidase family. (534 aa)
	RR48_06373	Uncharacterized protein. (819 aa)
	RR48_09849	Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (339 aa)
	RR48_08322	Apyrase; Belongs to the 5'-nucleotidase family. (541 aa)
	RR48_10056	Histidine triad nucleotide-binding protein 1. (127 aa)
	RR48_10071	Ornithine decarboxylase antizyme. (209 aa)
	RR48_10518	5'-nucleotidase; Belongs to the 5'-nucleotidase family. (540 aa)
	RR48_10492	S-adenosylmethionine decarboxylase proenzyme. (369 aa)
	RR48_10520	Protein 5NUC; Belongs to the 5'-nucleotidase family. (515 aa)
	RR48_08338	Adenosine deaminase CECR1. (500 aa)
	RR48_09883	Peroxisomal N(1)-acetyl-spermine/spermidine oxidase. (644 aa)
	RR48_10491	S-adenosylmethionine decarboxylase proenzyme. (70 aa)
	RR48_06830	Spermine synthase. (372 aa)
	RR48_09080	Allantoinase. (466 aa)
	RR48_07061	Deoxycytidylate deaminase. (346 aa)
	RR48_06818	Uracil phosphoribosyltransferase-like. (167 aa)
	RR48_09313	Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (504 aa)
	RR48_08563	Histidine triad nucleotide-binding protein 1. (343 aa)
	RR48_08566	Nitrilase and fragile histidine triad fusion protein NitFhit. (92 aa)
	RR48_06598	Putative uridine nucleosidase 2. (1494 aa)
	RR48_07341	Guanine deaminase. (592 aa)
	RR48_12010	Enolase-phosphatase E1. (726 aa)
	RR48_11958	tRNA-specific adenosine deaminase 2. (163 aa)
	RR48_10597	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (158 aa)
	RR48_13892	AMP deaminase 2. (557 aa)
	RR48_08567	Bis(5'-adenosyl)-triphosphatase. (411 aa)
	RR48_12501	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (352 aa)
	RR48_11113	S-AdoMet_synt_N domain-containing protein. (151 aa)

Your Current Organism:

Papilio machaon

NCBI taxonomy Id: 76193
Other names: Old World swallowtail, P. machaon, artemisia swallowtail, common yellow swallowtail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RR48_00265	RR48_08566	A0A0N1IJF8	A0A194RJ64	Uncharacterized protein.	Nitrilase and fragile histidine triad fusion protein NitFhit.	0.692
RR48_00265	RR48_08567	A0A0N1IJF8	A0A194RN05	Uncharacterized protein.	Bis(5'-adenosyl)-triphosphatase.	0.692
RR48_00345	RR48_02814	A0A0N1IKS4	A0A0N1IHY1	Uncharacterized protein.	Uridine phosphorylase 1.	0.410
RR48_00345	RR48_03130	A0A0N1IKS4	A0A0N1PH14	Uncharacterized protein.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.473
RR48_00345	RR48_05716	A0A0N1IKS4	A0A0N1I7E1	Uncharacterized protein.	Single-strand selective monofunctional uracil DNA glycosylase.	0.405
RR48_00345	RR48_06373	A0A0N1IKS4	A0A194R2I6	Uncharacterized protein.	Uncharacterized protein.	0.410
RR48_00345	RR48_06598	A0A0N1IKS4	A0A194RJR2	Uncharacterized protein.	Putative uridine nucleosidase 2.	0.513
RR48_00345	RR48_07341	A0A0N1IKS4	A0A194RKJ7	Uncharacterized protein.	Guanine deaminase.	0.410
RR48_00345	RR48_07562	A0A0N1IKS4	A0A194QUB6	Uncharacterized protein.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.482
RR48_00345	RR48_09010	A0A0N1IKS4	A0A194QZE7	Uncharacterized protein.	Rhythmically expressed gene 2 protein.	0.443
RR48_00345	RR48_10217	A0A0N1IKS4	A0A194R010	Uncharacterized protein.	tRNA-specific adenosine deaminase-like protein 3.	0.405
RR48_00345	RR48_11958	A0A0N1IKS4	A0A194RLB6	Uncharacterized protein.	tRNA-specific adenosine deaminase 2.	0.405
RR48_00345	RR48_14751	A0A0N1IKS4	A0A194R081	Uncharacterized protein.	Uridine phosphorylase 1.	0.410
RR48_00389	RR48_03130	A0A0N1IHU5	A0A0N1PH14	Xanthine dehydrogenase.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.427
RR48_00389	RR48_06373	A0A0N1IHU5	A0A194R2I6	Xanthine dehydrogenase.	Uncharacterized protein.	0.449
RR48_00389	RR48_07341	A0A0N1IHU5	A0A194RKJ7	Xanthine dehydrogenase.	Guanine deaminase.	0.449
RR48_00389	RR48_07562	A0A0N1IHU5	A0A194QUB6	Xanthine dehydrogenase.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.462
RR48_00389	RR48_14813	A0A0N1IHU5	A0A194R0Y5	Xanthine dehydrogenase.	Xanthine dehydrogenase.	0.481
RR48_00566	RR48_00853	A0A0N1IHX0	A0A0N1IC27	5'-nucleotidase.	Apyrase; Belongs to the 5'-nucleotidase family.	0.518
RR48_00566	RR48_02495	A0A0N1IHX0	A0A0N0PB47	5'-nucleotidase.	Trifunctional nucleotide phosphoesterase protein YfkN.	0.414