node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LKI_00300 | LKI_00395 | LKI_00300 | LKI_00395 | Hypothetical protein; COG0328 Ribonuclease HI. | Hypothetical protein; COG0629 Single-stranded DNA-binding protein. | 0.531 |
LKI_00300 | LKI_04440 | LKI_00300 | LKI_04440 | Hypothetical protein; COG0328 Ribonuclease HI. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.531 |
LKI_00300 | LKI_09040 | LKI_00300 | LKI_09040 | Hypothetical protein; COG0328 Ribonuclease HI. | EbsB protein; COG0328 Ribonuclease HI. | 0.900 |
LKI_00300 | topA | LKI_00300 | LKI_04690 | Hypothetical protein; COG0328 Ribonuclease HI. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.644 |
LKI_00395 | LKI_00300 | LKI_00395 | LKI_00300 | Hypothetical protein; COG0629 Single-stranded DNA-binding protein. | Hypothetical protein; COG0328 Ribonuclease HI. | 0.531 |
LKI_00395 | LKI_04440 | LKI_00395 | LKI_04440 | Hypothetical protein; COG0629 Single-stranded DNA-binding protein. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.900 |
LKI_00395 | LKI_09040 | LKI_00395 | LKI_09040 | Hypothetical protein; COG0629 Single-stranded DNA-binding protein. | EbsB protein; COG0328 Ribonuclease HI. | 0.531 |
LKI_00395 | topA | LKI_00395 | LKI_04690 | Hypothetical protein; COG0629 Single-stranded DNA-binding protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.982 |
LKI_03880 | topA | LKI_03880 | LKI_04690 | COG0514 Superfamily II DNA helicase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.999 |
LKI_04440 | LKI_00300 | LKI_04440 | LKI_00300 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Hypothetical protein; COG0328 Ribonuclease HI. | 0.531 |
LKI_04440 | LKI_00395 | LKI_04440 | LKI_00395 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Hypothetical protein; COG0629 Single-stranded DNA-binding protein. | 0.900 |
LKI_04440 | LKI_09040 | LKI_04440 | LKI_09040 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | EbsB protein; COG0328 Ribonuclease HI. | 0.531 |
LKI_04440 | topA | LKI_04440 | LKI_04690 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.982 |
LKI_09040 | LKI_00300 | LKI_09040 | LKI_00300 | EbsB protein; COG0328 Ribonuclease HI. | Hypothetical protein; COG0328 Ribonuclease HI. | 0.900 |
LKI_09040 | LKI_00395 | LKI_09040 | LKI_00395 | EbsB protein; COG0328 Ribonuclease HI. | Hypothetical protein; COG0629 Single-stranded DNA-binding protein. | 0.531 |
LKI_09040 | LKI_04440 | LKI_09040 | LKI_04440 | EbsB protein; COG0328 Ribonuclease HI. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.531 |
LKI_09040 | topA | LKI_09040 | LKI_04690 | EbsB protein; COG0328 Ribonuclease HI. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.644 |
topA | LKI_00300 | LKI_04690 | LKI_00300 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Hypothetical protein; COG0328 Ribonuclease HI. | 0.644 |
topA | LKI_00395 | LKI_04690 | LKI_00395 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Hypothetical protein; COG0629 Single-stranded DNA-binding protein. | 0.982 |
topA | LKI_03880 | LKI_04690 | LKI_03880 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | COG0514 Superfamily II DNA helicase. | 0.999 |