STRINGSTRING
LKI_01045 LKI_01045 LKI_05535 LKI_05535 thyA thyA LKI_08790 LKI_08790 LKI_09380 LKI_09380 LKI_09475 LKI_09475
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LKI_01045COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (431 aa)
LKI_05535FolC family protein; COG0285 Folylpolyglutamate synthase. (393 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (322 aa)
LKI_08790COG0207 Thymidylate synthase. (332 aa)
LKI_09380COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (443 aa)
LKI_09475Hypothetical protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (171 aa)
Your Current Organism:
Leuconostoc kimchii
NCBI taxonomy Id: 762051
Other names: L. kimchii IMSNU 11154, Leuconostoc kimchii IMSNU 11154, Leuconostoc kimchii str. IMSNU 11154, Leuconostoc kimchii strain IMSNU 11154
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