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| | LKI_00040 | COG2364 Predicted membrane protein. (211 aa) |
| | LKI_00205 | ImpB/MucB/SamB family protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; Belongs to the DNA polymerase type-Y family. (440 aa) |
| | LKI_00435 | ImpB/MucB/SamB family protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; Belongs to the DNA polymerase type-Y family. (440 aa) |
| | galK | Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (390 aa) |
| | galT | COG4468 Galactose-1-phosphate uridyltransferase. (504 aa) |
| | LKI_00800 | Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIC, probable sorbose specific; COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC. (267 aa) |
| | LKI_00805 | Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIB, probable sorbose specific; COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB. (156 aa) |
| | LKI_01010 | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (271 aa) |
| | LKI_01055 | GTP cyclohydrolase I; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. (166 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa) |
| | LKI_01420 | ATP-dependent helicase DinG; COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. (801 aa) |
| | LKI_01425 | COG1577 Mevalonate kinase. (310 aa) |
| | LKI_01445 | Ribose-phosphate pyrophosphokinase; COG0462 Phosphoribosylpyrophosphate synthetase. (324 aa) |
| | rbsK | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (309 aa) |
| | polC | DNA-directed DNA polymerase III, alpha chain PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1437 aa) |
| | LKI_01500 | Phosphatidate cytidylyltransferase; COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. (264 aa) |
| | LKI_01540 | COG3407 Mevalonate pyrophosphate decarboxylase. (316 aa) |
| | LKI_01545 | COG1577 Mevalonate kinase. (341 aa) |
| | LKI_02290 | COG3641 Predicted membrane protein, putative toxin regulator. (380 aa) |
| | LKI_02320 | COG1440 Phosphotransferase system cellobiose-specific component IIB. (107 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (320 aa) |
| | LKI_02410 | Hypothetical protein; COG1461 Predicted kinase related to dihydroxyacetone kinase. (565 aa) |
| | LKI_02430 | Hypothetical protein; COG1564 Thiamine pyrophosphokinase. (214 aa) |
| | LKI_02445 | COG0515 Serine/threonine protein kinase. (643 aa) |
| | LKI_02495 | Transcription regulator; COG1056 Nicotinamide mononucleotide adenylyltransferase. (388 aa) |
| | LKI_02530 | Exonuclease; COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. (177 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (158 aa) |
| | LKI_02710 | Gluconate kinase; COG1070 Sugar (pentulose and hexulose) kinases; Belongs to the FGGY kinase family. (512 aa) |
| | udk | COG0572 Uridine kinase. (213 aa) |
| | rpoE | DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. (191 aa) |
| | LKI_02875 | 2-dehydro-3-deoxygluconokinase; COG0524 Sugar kinases, ribokinase family. (320 aa) |
| | LKI_02955 | COG0095 Lipoate-protein ligase A. (336 aa) |
| | LKI_03075 | DNA-directed DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for in [...] (377 aa) |
| | LKI_03100 | Hypothetical protein; COG1983 Putative stress-responsive transcriptional regulator. (88 aa) |
| | LKI_03250 | Hypothetical protein; COG1070 Sugar (pentulose and hexulose) kinases. (540 aa) |
| | rbsK-2 | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (312 aa) |
| | LKI_03700 | Histidine kinase; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid. (437 aa) |
| | LKI_03730 | Beta-glucosides PTS, EIIBCA; COG1264 Phosphotransferase system IIB components. (628 aa) |
| | LKI_03810 | Sensor protein kinase; COG0642 Signal transduction histidine kinase. (292 aa) |
| | LKI_03860 | Histidine protein kinase; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain. (275 aa) |
| | LKI_04065 | Sugar specific permease (putative); COG2364 Predicted membrane protein. (226 aa) |
| | citG | triphosphoribosyl-dephosphocoenzyme-A synthase; COG3697 Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase). (465 aa) |
| | LKI_04150 | COG1940 Transcriptional regulator/sugar kinase. (300 aa) |
| | LKI_04205 | DNA topology modulation protein FLAR-related protein; COG0563 Adenylate kinase and related kinases. (160 aa) |
| | LKI_04350 | COG4585 Signal transduction histidine kinase. (401 aa) |
| | LKI_04450 | Exopolyphosphatase-related protein (putative); Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. (676 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa) |
| | LKI_04525 | COG5002 Signal transduction histidine kinase. (619 aa) |
| | LKI_04550 | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (268 aa) |
| | LKI_04615 | Beta-glucosides PTS, EIIABC; COG2190 Phosphotransferase system IIA components. (51 aa) |
| | LKI_04620 | Beta-glucoside-specific PTS system IIABC component; COG2190 Phosphotransferase system IIA components. (634 aa) |
| | LKI_04645 | COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism. (530 aa) |
| | LKI_04675 | COG1316 Transcriptional regulator. (402 aa) |
| | LKI_04780 | COG0194 Guanylate kinase. (193 aa) |
| | LKI_04790 | COG3641 Predicted membrane protein, putative toxin regulator. (349 aa) |
| | acpS | Holo-[acyl-carrier protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (136 aa) |
| | LKI_04860 | COG1316 Transcriptional regulator. (390 aa) |
| | LKI_04970 | COG0642 Signal transduction histidine kinase. (361 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (419 aa) |
| | thiM | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (258 aa) |
| | LKI_05100 | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (277 aa) |
| | LKI_05130 | COG2035 Predicted membrane protein. (278 aa) |
| | proB | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (271 aa) |
| | coaE | Hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (206 aa) |
| | LKI_05475 | Sugar specific permease (putative). (244 aa) |
| | LKI_05485 | Fructokinase; COG1940 Transcriptional regulator/sugar kinase. (288 aa) |
| | LKI_05635 | Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (324 aa) |
| | LKI_05655 | COG3641 Predicted membrane protein, putative toxin regulator. (412 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (212 aa) |
| | LKI_05730 | COG0642 Signal transduction histidine kinase. (368 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (198 aa) |
| | rpoZ | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (70 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (270 aa) |
| | LKI_06115 | Surfactin biosynthesis-related protein, SFP; COG2091 Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (219 aa) |
| | LKI_06235 | Putative histidine kinase of the competence regulon, ComD; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain. (435 aa) |
| | LKI_06405 | COG1072 Panthothenate kinase. (224 aa) |
| | pgk | COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (405 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (187 aa) |
| | rpoA | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (314 aa) |
| | rpoB | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1200 aa) |
| | rpoC | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1220 aa) |
| | ppk | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (714 aa) |
| | dnaX | DNA-directed DNA polymerase III, gamma/tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (594 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (214 aa) |
| | LKI_06945 | DNA polymerase III, delta prime subunit; COG0470 ATPase involved in DNA replication. (308 aa) |
| | LKI_06975 | COG1428 Deoxynucleoside kinases. (213 aa) |
| | LKI_07080 | Sensor protein kinase; COG0642 Signal transduction histidine kinase. (427 aa) |
| | tdk | COG1435 Thymidine kinase. (201 aa) |
| | LKI_07215 | Phosphoenolpyruvate--protein phosphatase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (571 aa) |
| | LKI_07330 | PTS system, IIAB component, mannose/fructose/sorbose family; COG2893 Phosphotransferase system, mannose/fructose-specific component IIA. (316 aa) |
| | LKI_07335 | COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC. (269 aa) |
| | LKI_07510 | Hypothetical protein; COG0534 Na+-driven multidrug efflux pump. (420 aa) |
| | LKI_07675 | Transcription regulator; COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase. (303 aa) |
| | LKI_07690 | Hypothetical protein; COG5503 Uncharacterized conserved small protein. (70 aa) |
| | glmU | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (459 aa) |
| | LKI_07785 | Hypothetical protein; COG1466 DNA polymerase III, delta subunit. (332 aa) |
| | LKI_07815 | Transcription regulator; COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase. (329 aa) |
| | LKI_07870 | Teichoic acid biosynthesis protein; COG0463 Glycosyltransferases involved in cell wall biogenesis. (1180 aa) |
| | LKI_07995 | Hypothetical protein. (113 aa) |
| | LKI_08065 | COG0105 Nucleoside diphosphate kinase. (137 aa) |
| | dacA | Hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (271 aa) |
| | LKI_08135 | COG1440 Phosphotransferase system cellobiose-specific component IIB. (104 aa) |
| | LKI_08140 | COG3711 Transcriptional antiterminator. (665 aa) |
| | LKI_08155 | PTS system, IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (447 aa) |
| | LKI_08265 | Cardiolipin synthetase 2; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (477 aa) |
| | LKI_08285 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (193 aa) |
| | LKI_08305 | COG0642 Signal transduction histidine kinase. (451 aa) |
| | hprK | Bifunctional protein: HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisabl [...] (320 aa) |
| | LKI_08355 | UTP--glucose-1-phosphate uridylyltransferase; COG1210 UDP-glucose pyrophosphorylase. (290 aa) |
| | dinB | DNA-damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (361 aa) |
| | LKI_08405 | Hypothetical protein; COG1455 Phosphotransferase system cellobiose-specific component IIC. (405 aa) |
| | LKI_08475 | COG1428 Deoxynucleoside kinases. (210 aa) |
| | LKI_08505 | Hypothetical protein; COG3711 Transcriptional antiterminator. (454 aa) |
| | LKI_08525 | Phosphoenolpyruvate-dependent sugar phosphotransferase systemEIIB, probable galactitol specific; COG3414 Phosphotransferase system, galactitol-specific IIB component. (95 aa) |
| | LKI_08540 | COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (305 aa) |
| | LKI_08545 | PTS system, fructose specific IIABC components; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). (642 aa) |
| | LKI_08585 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (290 aa) |
| | LKI_08600 | Glycosyltransferase; COG1190 Lysyl-tRNA synthetase (class II). (319 aa) |
| | LKI_08615 | Membrane-bound protein; COG0463 Glycosyltransferases involved in cell wall biogenesis. (978 aa) |
| | LKI_08635 | Membrane-bound protein; COG0463 Glycosyltransferases involved in cell wall biogenesis. (890 aa) |
| | LKI_08640 | Hypothetical protein; COG1887 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC. (500 aa) |
| | LKI_08735 | GTP pyrophosphokinase (putative); COG2357 Uncharacterized protein conserved in bacteria. (192 aa) |
| | ppnK | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (263 aa) |
| | LKI_08755 | COG1316 Transcriptional regulator. (329 aa) |
| | LKI_08910 | Glucokinase; COG1940 Transcriptional regulator/sugar kinase. (329 aa) |
| | LKI_08940 | COG0615 Cytidylyltransferase. (143 aa) |
| | polA | DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (895 aa) |
| | LKI_09025 | Sucrose PTS, EIIBCA; COG1264 Phosphotransferase system IIB components. (658 aa) |
| | LKI_09035 | Fructokinase; COG1940 Transcriptional regulator/sugar kinase. (290 aa) |
| | LKI_09080 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (749 aa) |
| | LKI_09165 | Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family. (314 aa) |
| | LKI_09365 | COG3641 Predicted membrane protein, putative toxin regulator. (378 aa) |
| | cmk | Cmk; COG0283 Cytidylate kinase. (225 aa) |
| | cca | Polynucleotide adenylyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (403 aa) |
| | LKI_09845 | COG0587 DNA polymerase III, alpha subunit. (1113 aa) |
| | LKI_09850 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (473 aa) |
| | LKI_09870 | COG0818 Diacylglycerol kinase. (160 aa) |
| | LKI_09890 | COG0527 Aspartokinases; Belongs to the aspartokinase family. (452 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (294 aa) |
| | ackA-2 | Acetate/propionate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (415 aa) |
| | LKI_09955 | COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB. (164 aa) |
| | LKI_09960 | COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC. (287 aa) |
| | dnaG | DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (618 aa) |
