(57 nodes) Mixed, incl. DNA biosynthetic process, and HDR through Single Strand Annealing (SSA) network (Phycomyces blakesleeanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A162N356	AAA domain-containing protein. (603 aa)
	A0A162N615	AAA domain-containing protein. (335 aa)
	A0A162N8U1	Rad51 domain-containing protein. (57 aa)
	A0A162NC51	Uncharacterized protein. (1062 aa)
	A0A162NDE4	Uncharacterized protein. (249 aa)
	A0A162NE62	Uncharacterized protein. (756 aa)
	A0A162PIM8	Uncharacterized protein. (133 aa)
	A0A162PL32	Uncharacterized protein. (676 aa)
	A0A162PVA1	AAA_12 domain-containing protein. (1367 aa)
	A0A162Q3V1	Uncharacterized protein. (267 aa)
	A0A162Q4N2	XPGI domain-containing protein. (152 aa)
	A0A162T215	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family. (392 aa)
	A0A162TQZ6	EF-hand domain-containing protein. (180 aa)
	A0A162TTU4	Uncharacterized protein. (314 aa)
	A0A162TWP5	Homeodomain-like DNA binding domain-containing transcription factor. (277 aa)
	A0A162U3K3	UmuC domain-containing protein. (406 aa)
	A0A162U944	DNA ligase. (639 aa)
	A0A162U9H3	Uncharacterized protein. (422 aa)
	A0A162UGC7	DNA polymerase. (828 aa)
	A0A162US08	ANK_REP_REGION domain-containing protein. (110 aa)
	A0A162UUM4	Uncharacterized protein; Belongs to the RecA family. (356 aa)
	A0A162V3B0	Uncharacterized protein. (311 aa)
	A0A162XBY4	Uncharacterized protein. (757 aa)
	A0A162XGQ2	Vezatin domain-containing protein. (595 aa)
	A0A162XJI2	Uncharacterized protein. (292 aa)
	A0A162XRF7	Uncharacterized protein. (218 aa)
	A0A162XTE5	Uncharacterized protein. (618 aa)
	A0A162YIW6	Uncharacterized protein. (172 aa)
	A0A162ZWE1	AAA domain-containing protein. (337 aa)
	A0A163APY4	Uncharacterized protein. (902 aa)
	A0A163D1U8	DNA polymerase. (1072 aa)
	A0A163DCB2	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (260 aa)
	A0A163DVH2	BRCT domain-containing protein. (702 aa)
	A0A163EJQ5	Uncharacterized protein. (443 aa)
	A0A167JD07	Uncharacterized protein. (349 aa)
	A0A167JWZ5	Uncharacterized protein. (617 aa)
	A0A167KG19	AAA domain-containing protein. (357 aa)
	A0A167KHZ5	Uncharacterized protein. (430 aa)
	A0A167KUJ8	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (518 aa)
	A0A167KUM1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
	A0A167L178	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (601 aa)
	A0A167L451	Checkpoint protein; Belongs to the HUS1 family. (271 aa)
	A0A167L4L7	UmuC domain-containing protein. (258 aa)
	A0A167L655	3'-5' exonuclease domain-containing protein. (324 aa)
	A0A167L9A7	Uncharacterized protein. (712 aa)
	A0A167LPH8	Uncharacterized protein. (860 aa)
	A0A167MNC4	UmuC domain-containing protein. (609 aa)
	A0A167NFT6	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (683 aa)
	A0A167NX38	Uncharacterized protein. (270 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (375 aa)
	A0A167P417	Rad51 domain-containing protein. (100 aa)
	A0A167PC19	Vezatin domain-containing protein. (595 aa)
	A0A167PCI8	HORMA domain-containing protein. (166 aa)
	A0A167PY74	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (632 aa)
	A0A167Q311	Uncharacterized protein. (173 aa)
	A0A167QMF1	XPGN domain-containing protein. (430 aa)
	A0A167QTH9	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (333 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A162N356	A0A162N615	A0A162N356	A0A162N615	AAA domain-containing protein.	AAA domain-containing protein.	0.999
A0A162N356	A0A162N8U1	A0A162N356	A0A162N8U1	AAA domain-containing protein.	Rad51 domain-containing protein.	0.822
A0A162N356	A0A162NC51	A0A162N356	A0A162NC51	AAA domain-containing protein.	Uncharacterized protein.	0.687
A0A162N356	A0A162NDE4	A0A162N356	A0A162NDE4	AAA domain-containing protein.	Uncharacterized protein.	0.817
A0A162N356	A0A162NE62	A0A162N356	A0A162NE62	AAA domain-containing protein.	Uncharacterized protein.	0.861
A0A162N356	A0A162PIM8	A0A162N356	A0A162PIM8	AAA domain-containing protein.	Uncharacterized protein.	0.847
A0A162N356	A0A162PL32	A0A162N356	A0A162PL32	AAA domain-containing protein.	Uncharacterized protein.	0.605
A0A162N356	A0A162PVA1	A0A162N356	A0A162PVA1	AAA domain-containing protein.	AAA_12 domain-containing protein.	0.780
A0A162N356	A0A162Q3V1	A0A162N356	A0A162Q3V1	AAA domain-containing protein.	Uncharacterized protein.	0.784
A0A162N356	A0A162Q4N2	A0A162N356	A0A162Q4N2	AAA domain-containing protein.	XPGI domain-containing protein.	0.825
A0A162N356	A0A162T215	A0A162N356	A0A162T215	AAA domain-containing protein.	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family.	0.896
A0A162N356	A0A162TQZ6	A0A162N356	A0A162TQZ6	AAA domain-containing protein.	EF-hand domain-containing protein.	0.699
A0A162N356	A0A162TTU4	A0A162N356	A0A162TTU4	AAA domain-containing protein.	Uncharacterized protein.	0.800
A0A162N356	A0A162TWP5	A0A162N356	A0A162TWP5	AAA domain-containing protein.	Homeodomain-like DNA binding domain-containing transcription factor.	0.683
A0A162N356	A0A162U3K3	A0A162N356	A0A162U3K3	AAA domain-containing protein.	UmuC domain-containing protein.	0.709
A0A162N356	A0A162U944	A0A162N356	A0A162U944	AAA domain-containing protein.	DNA ligase.	0.878
A0A162N356	A0A162UGC7	A0A162N356	A0A162UGC7	AAA domain-containing protein.	DNA polymerase.	0.806
A0A162N356	A0A162US08	A0A162N356	A0A162US08	AAA domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.791
A0A162N356	A0A162UUM4	A0A162N356	A0A162UUM4	AAA domain-containing protein.	Uncharacterized protein; Belongs to the RecA family.	0.665
A0A162N356	A0A162V3B0	A0A162N356	A0A162V3B0	AAA domain-containing protein.	Uncharacterized protein.	0.901