(11 nodes) HDR through Single Strand Annealing (SSA), and Replication factor A protein-like network (Phycomyces blakesleeanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A162NDE4	Uncharacterized protein. (249 aa)
	A0A162PIM8	Uncharacterized protein. (133 aa)
	A0A162PVA1	AAA_12 domain-containing protein. (1367 aa)
	A0A162TTU4	Uncharacterized protein. (314 aa)
	A0A163DCB2	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (260 aa)
	A0A167KUJ8	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (518 aa)
	A0A167L178	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (601 aa)
	A0A167L655	3'-5' exonuclease domain-containing protein. (324 aa)
	A0A167L9A7	Uncharacterized protein. (712 aa)
	A0A167NFT6	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (683 aa)
	A0A167QMF1	XPGN domain-containing protein. (430 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A162NDE4	A0A162PIM8	Uncharacterized protein.	Uncharacterized protein.	0.984
A0A162NDE4	A0A162PVA1	Uncharacterized protein.	AAA_12 domain-containing protein.	0.890
A0A162NDE4	A0A163DCB2	Uncharacterized protein.	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.978
A0A162NDE4	A0A167KUJ8	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.972
A0A162NDE4	A0A167L178	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.999
A0A162NDE4	A0A167L655	Uncharacterized protein.	3'-5' exonuclease domain-containing protein.	0.999
A0A162NDE4	A0A167L9A7	Uncharacterized protein.	Uncharacterized protein.	0.999
A0A162NDE4	A0A167NFT6	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.974
A0A162NDE4	A0A167QMF1	Uncharacterized protein.	XPGN domain-containing protein.	0.751
A0A162PIM8	A0A162NDE4	Uncharacterized protein.	Uncharacterized protein.	0.984
A0A162PIM8	A0A162PVA1	Uncharacterized protein.	AAA_12 domain-containing protein.	0.895
A0A162PIM8	A0A162TTU4	Uncharacterized protein.	Uncharacterized protein.	0.968
A0A162PIM8	A0A163DCB2	Uncharacterized protein.	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.955
A0A162PIM8	A0A167KUJ8	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.971
A0A162PIM8	A0A167L178	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.997
A0A162PIM8	A0A167L655	Uncharacterized protein.	3'-5' exonuclease domain-containing protein.	0.999
A0A162PIM8	A0A167L9A7	Uncharacterized protein.	Uncharacterized protein.	0.996
A0A162PIM8	A0A167NFT6	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.880
A0A162PIM8	A0A167QMF1	Uncharacterized protein.	XPGN domain-containing protein.	0.865
A0A162PVA1	A0A162NDE4	AAA_12 domain-containing protein.	Uncharacterized protein.	0.890