(15 nodes) Base-excision repair, and WLM domain network (Phycomyces blakesleeanus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	A0A162PLZ4	UDG domain-containing protein. (201 aa)
	UNG1	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (224 aa)
	A0A162THI0	Transcription factor TFIID, C-terminal. (364 aa)
	A0A162XPX5	Uncharacterized protein. (241 aa)
	A0A162Y1A6	Uncharacterized protein. (170 aa)
	A0A162YDA6	Uncharacterized protein. (256 aa)
	A0A163B4W0	Uncharacterized protein. (137 aa)
	A0A163DEP7	Uncharacterized protein. (306 aa)
	A0A163DJH1	Uncharacterized protein. (406 aa)
	A0A163ERS1	ENDO3c domain-containing protein. (306 aa)
	A0A167LR58	Uncharacterized protein. (469 aa)
	A0A167LYT8	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (319 aa)
	A0A167NZV0	Uncharacterized protein. (489 aa)
	A0A167PRE9	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (411 aa)
	NTH1	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (319 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A162PLZ4	A0A162THI0	A0A162PLZ4	A0A162THI0	UDG domain-containing protein.	Transcription factor TFIID, C-terminal.	0.446
A0A162PLZ4	A0A167LYT8	A0A162PLZ4	A0A167LYT8	UDG domain-containing protein.	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.	0.801
A0A162PLZ4	A0A167PRE9	A0A162PLZ4	A0A167PRE9	UDG domain-containing protein.	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.	0.801
A0A162PLZ4	NTH1	A0A162PLZ4	A0A167R1T7	UDG domain-containing protein.	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	0.467
A0A162PLZ4	UNG1	A0A162PLZ4	A0A162Q1V3	UDG domain-containing protein.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.467
A0A162THI0	A0A162PLZ4	A0A162THI0	A0A162PLZ4	Transcription factor TFIID, C-terminal.	UDG domain-containing protein.	0.446
A0A162THI0	A0A162Y1A6	A0A162THI0	A0A162Y1A6	Transcription factor TFIID, C-terminal.	Uncharacterized protein.	0.432
A0A162THI0	A0A163B4W0	A0A162THI0	A0A163B4W0	Transcription factor TFIID, C-terminal.	Uncharacterized protein.	0.432
A0A162THI0	A0A167LR58	A0A162THI0	A0A167LR58	Transcription factor TFIID, C-terminal.	Uncharacterized protein.	0.432
A0A162THI0	A0A167LYT8	A0A162THI0	A0A167LYT8	Transcription factor TFIID, C-terminal.	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.	0.856
A0A162THI0	A0A167NZV0	A0A162THI0	A0A167NZV0	Transcription factor TFIID, C-terminal.	Uncharacterized protein.	0.461
A0A162THI0	A0A167PRE9	A0A162THI0	A0A167PRE9	Transcription factor TFIID, C-terminal.	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.	0.860
A0A162THI0	NTH1	A0A162THI0	A0A167R1T7	Transcription factor TFIID, C-terminal.	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	0.609
A0A162THI0	UNG1	A0A162THI0	A0A162Q1V3	Transcription factor TFIID, C-terminal.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.475
A0A162XPX5	A0A162Y1A6	A0A162XPX5	A0A162Y1A6	Uncharacterized protein.	Uncharacterized protein.	0.432
A0A162XPX5	A0A163B4W0	A0A162XPX5	A0A163B4W0	Uncharacterized protein.	Uncharacterized protein.	0.432
A0A162XPX5	A0A167LR58	A0A162XPX5	A0A167LR58	Uncharacterized protein.	Uncharacterized protein.	0.432
A0A162XPX5	A0A167LYT8	A0A162XPX5	A0A167LYT8	Uncharacterized protein.	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.	0.789
A0A162XPX5	A0A167PRE9	A0A162XPX5	A0A167PRE9	Uncharacterized protein.	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.	0.789
A0A162XPX5	NTH1	A0A162XPX5	A0A167R1T7	Uncharacterized protein.	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	0.488