(46 nodes) RNA Polymerase II Promoter Escape, and DNA binding, bending network (Phycomyces blakesleeanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A162N7H7	HMG box domain-containing protein. (89 aa)
	A0A162NAF9	TATA box binding protein associated factor. (453 aa)
	A0A162NDJ3	Uncharacterized protein. (232 aa)
	A0A162PJ30	Uncharacterized protein. (233 aa)
	A0A162Q141	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (313 aa)
	A0A162T8U4	Protein kinase domain-containing protein. (353 aa)
	A0A162T9H7	Helicase ATP-binding domain-containing protein. (1214 aa)
	A0A162TN21	Uncharacterized protein. (147 aa)
	A0A162TV25	Uncharacterized protein. (700 aa)
	A0A162UGY5	TFIID_20kDa domain-containing protein. (103 aa)
	A0A162UM41	Uncharacterized protein. (143 aa)
	A0A162V0U7	Uncharacterized protein. (116 aa)
	A0A162VB95	HELICc2 domain-containing protein. (486 aa)
	A0A162X8R1	Helicase ATP-binding domain-containing protein. (767 aa)
	A0A162XE97	Uncharacterized protein. (776 aa)
	A0A162XK73	Uncharacterized protein. (315 aa)
	A0A162XXD6	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (453 aa)
	A0A162Y6Z1	Uncharacterized protein. (246 aa)
	A0A162YHE4	TFIIB-type domain-containing protein. (293 aa)
	A0A162ZH60	Uncharacterized protein. (244 aa)
	A0A162ZJ50	Uncharacterized protein. (419 aa)
	A0A162ZVW2	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (284 aa)
	A0A162ZY90	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (410 aa)
	A0A163AKQ3	TAFII28 domain-containing protein. (118 aa)
	A0A163AN76	BTP domain-containing protein. (321 aa)
	A0A163D9S9	F-box domain-containing protein. (277 aa)
	A0A167JA28	HMG box domain-containing protein. (105 aa)
	A0A167JHR9	HTH TFE/IIEalpha-type domain-containing protein. (430 aa)
	A0A167JU51	RING-type domain-containing protein. (105 aa)
	A0A167JY79	Uncharacterized protein. (296 aa)
	A0A167KRF2	HMG box domain-containing protein. (105 aa)
	A0A167KXS2	HMG box domain-containing protein. (356 aa)
	A0A167KYZ7	Uncharacterized protein. (647 aa)
	A0A167LFS1	Bromo domain-containing protein. (72 aa)
	A0A167LFS7	Uncharacterized protein. (849 aa)
	A0A167MAP9	Transcription factor TFIID, C-terminal, TATA-box binding transcription factor. (223 aa)
	A0A167ML90	Uncharacterized protein. (129 aa)
	A0A167MVT5	TFIIB-type domain-containing protein. (338 aa)
	A0A167N1D2	BSD domain-containing protein. (624 aa)
	A0A167N403	Uncharacterized protein. (2314 aa)
	A0A167NX81	Uncharacterized protein. (170 aa)
	A0A167P3A9	Uncharacterized protein. (490 aa)
	A0A167PTU1	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (112 aa)
	A0A167QFB1	Cyclin; Belongs to the cyclin family. (338 aa)
	A0A167QQ08	Uncharacterized protein. (75 aa)
	A0A167RCM9	Uncharacterized protein. (116 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A162N7H7	A0A162NAF9	HMG box domain-containing protein.	TATA box binding protein associated factor.	0.738
A0A162N7H7	A0A162Q141	HMG box domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.732
A0A162N7H7	A0A162T8U4	HMG box domain-containing protein.	Protein kinase domain-containing protein.	0.589
A0A162N7H7	A0A162T9H7	HMG box domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.586
A0A162N7H7	A0A162TN21	HMG box domain-containing protein.	Uncharacterized protein.	0.735
A0A162N7H7	A0A162TV25	HMG box domain-containing protein.	Uncharacterized protein.	0.715
A0A162N7H7	A0A162UGY5	HMG box domain-containing protein.	TFIID_20kDa domain-containing protein.	0.720
A0A162N7H7	A0A162UM41	HMG box domain-containing protein.	Uncharacterized protein.	0.549
A0A162N7H7	A0A162V0U7	HMG box domain-containing protein.	Uncharacterized protein.	0.634
A0A162N7H7	A0A162VB95	HMG box domain-containing protein.	HELICc2 domain-containing protein.	0.586
A0A162N7H7	A0A162X8R1	HMG box domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.779
A0A162N7H7	A0A162XE97	HMG box domain-containing protein.	Uncharacterized protein.	0.795
A0A162N7H7	A0A162XK73	HMG box domain-containing protein.	Uncharacterized protein.	0.795
A0A162N7H7	A0A162XXD6	HMG box domain-containing protein.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.779
A0A162N7H7	A0A162YHE4	HMG box domain-containing protein.	TFIIB-type domain-containing protein.	0.637
A0A162N7H7	A0A162ZJ50	HMG box domain-containing protein.	Uncharacterized protein.	0.757
A0A162N7H7	A0A162ZVW2	HMG box domain-containing protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.735
A0A162N7H7	A0A162ZY90	HMG box domain-containing protein.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.758
A0A162N7H7	A0A163AKQ3	HMG box domain-containing protein.	TAFII28 domain-containing protein.	0.737
A0A162N7H7	A0A163D9S9	HMG box domain-containing protein.	F-box domain-containing protein.	0.758