(42 nodes) Mixed, incl. Preribosome, large subunit precursor, and Maturation of LSU-rRNA network (Phycomyces blakesleeanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A162N5C8	Brix domain-containing protein. (301 aa)
	A0A162NBT3	PUM-HD domain-containing protein. (554 aa)
	YTM1	Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (440 aa)
	A0A162PN29	Uncharacterized protein; Belongs to the DEAD box helicase family. (557 aa)
	A0A162T8G3	TRASH domain-containing protein. (159 aa)
	A0A162TI28	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (475 aa)
	A0A162TMJ8	Uncharacterized protein. (157 aa)
	A0A162TP48	WD_REPEATS_REGION domain-containing protein. (512 aa)
	A0A162TTC6	RNA helicase. (531 aa)
	A0A162TUU1	RNA helicase. (632 aa)
	A0A162TV89	Brix domain-containing protein. (323 aa)
	A0A162U0T6	GN3L_Grn1 domain-containing protein. (113 aa)
	A0A162UAC7	Uncharacterized protein. (251 aa)
	A0A162UEB0	Ribosomal_L28e domain-containing protein. (243 aa)
	A0A162UMT3	Brix domain-containing protein. (291 aa)
	A0A162UXW7	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (230 aa)
	A0A162W989	CP-type G domain-containing protein. (350 aa)
	A0A162X0U4	Uncharacterized protein; Belongs to the DEAD box helicase family. (517 aa)
	A0A162XUY6	Uncharacterized protein. (174 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (638 aa)
	A0A162ZTC4	Uncharacterized protein. (243 aa)
	NOP7	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (537 aa)
	A0A163B4Y4	Uncharacterized protein. (249 aa)
	A0A163EBT8	Uncharacterized protein. (267 aa)
	A0A167KA75	Uncharacterized protein. (699 aa)
	A0A167KGS6	RNA helicase. (596 aa)
	A0A167KX43	Uncharacterized protein. (227 aa)
	A0A167LM51	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (639 aa)
	A0A167M3D0	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (505 aa)
	A0A167MXT5	Uncharacterized protein. (569 aa)
	A0A167NPM2	Uncharacterized protein. (483 aa)
	A0A167P1W3	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (223 aa)
	A0A167P5G7	Uncharacterized protein. (386 aa)
	A0A167P7P3	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (577 aa)
	A0A167PH19	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
	A0A167QD21	RRM domain-containing protein. (149 aa)
	A0A167QGG7	Uncharacterized protein. (786 aa)
	A0A167QQG4	Uncharacterized protein. (265 aa)
	A0A167QR44	Uncharacterized protein. (260 aa)
	A0A167R143	Uncharacterized protein. (98 aa)
	A0A167R2V5	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (431 aa)
	A0A167R8Z2	Uncharacterized protein. (510 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A162N5C8	A0A162NBT3	A0A162N5C8	A0A162NBT3	Brix domain-containing protein.	PUM-HD domain-containing protein.	0.940
A0A162N5C8	A0A162PN29	A0A162N5C8	A0A162PN29	Brix domain-containing protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.766
A0A162N5C8	A0A162T8G3	A0A162N5C8	A0A162T8G3	Brix domain-containing protein.	TRASH domain-containing protein.	0.988
A0A162N5C8	A0A162TI28	A0A162N5C8	A0A162TI28	Brix domain-containing protein.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.899
A0A162N5C8	A0A162TMJ8	A0A162N5C8	A0A162TMJ8	Brix domain-containing protein.	Uncharacterized protein.	0.991
A0A162N5C8	A0A162TP48	A0A162N5C8	A0A162TP48	Brix domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.833
A0A162N5C8	A0A162TTC6	A0A162N5C8	A0A162TTC6	Brix domain-containing protein.	RNA helicase.	0.988
A0A162N5C8	A0A162TUU1	A0A162N5C8	A0A162TUU1	Brix domain-containing protein.	RNA helicase.	0.670
A0A162N5C8	A0A162TV89	A0A162N5C8	A0A162TV89	Brix domain-containing protein.	Brix domain-containing protein.	0.989
A0A162N5C8	A0A162U0T6	A0A162N5C8	A0A162U0T6	Brix domain-containing protein.	GN3L_Grn1 domain-containing protein.	0.980
A0A162N5C8	A0A162UAC7	A0A162N5C8	A0A162UAC7	Brix domain-containing protein.	Uncharacterized protein.	0.990
A0A162N5C8	A0A162UEB0	A0A162N5C8	A0A162UEB0	Brix domain-containing protein.	Ribosomal_L28e domain-containing protein.	0.998
A0A162N5C8	A0A162UMT3	A0A162N5C8	A0A162UMT3	Brix domain-containing protein.	Brix domain-containing protein.	0.995
A0A162N5C8	A0A162UXW7	A0A162N5C8	A0A162UXW7	Brix domain-containing protein.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.909
A0A162N5C8	A0A162W989	A0A162N5C8	A0A162W989	Brix domain-containing protein.	CP-type G domain-containing protein.	0.980
A0A162N5C8	A0A162X0U4	A0A162N5C8	A0A162X0U4	Brix domain-containing protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.663
A0A162N5C8	A0A162XUY6	A0A162N5C8	A0A162XUY6	Brix domain-containing protein.	Uncharacterized protein.	0.680
A0A162N5C8	A0A162ZTC4	A0A162N5C8	A0A162ZTC4	Brix domain-containing protein.	Uncharacterized protein.	0.965
A0A162N5C8	A0A163B4Y4	A0A162N5C8	A0A163B4Y4	Brix domain-containing protein.	Uncharacterized protein.	0.965
A0A162N5C8	A0A163EBT8	A0A162N5C8	A0A163EBT8	Brix domain-containing protein.	Uncharacterized protein.	0.998