(135 nodes) mRNA Splicing, and mRNA decay by 5 to 3 exoribonuclease network (Phycomyces blakesleeanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A162N3L9	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome. (1340 aa)
	A0A162N4I1	Uncharacterized protein. (463 aa)
	A0A162N558	Uncharacterized protein. (633 aa)
	A0A162N8H3	Matrin-type domain-containing protein. (469 aa)
	A0A162N8W7	PSP domain-containing protein. (443 aa)
	A0A162NBX5	CCCH-type zinc finger transcription factor. (156 aa)
	A0A162NCR2	Helicase C-terminal domain-containing protein. (193 aa)
	A0A162NFX4	Uncharacterized protein. (430 aa)
	A0A162NGK1	Uncharacterized protein. (634 aa)
	A0A162NIJ6	Sm domain-containing protein. (172 aa)
	A0A162NKQ8	CCCH-type zinc finger transcription factor. (186 aa)
	A0A162NLL2	Uncharacterized protein. (704 aa)
	LSM5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (84 aa)
	A0A162PJI7	Uncharacterized protein. (147 aa)
	A0A162PKM0	Uncharacterized protein; Belongs to the DEAD box helicase family. (553 aa)
	A0A162PQ22	Uncharacterized protein. (910 aa)
	A0A162PQY1	Uncharacterized protein. (849 aa)
	A0A162PSU0	Sm domain-containing protein. (84 aa)
	A0A162PTI1	SKIP_SNW domain-containing protein. (547 aa)
	LSM3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (105 aa)
	A0A162Q382	Uncharacterized protein. (598 aa)
	A0A162Q3Y5	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (183 aa)
	A0A162QAC5	Splicing factor subunit; Belongs to the SF3B5 family. (84 aa)
	A0A162T021	RRM domain-containing protein. (150 aa)
	A0A162TBE7	CPSF_A domain-containing protein. (1202 aa)
	A0A162THZ1	Small nuclear ribonucleoprotein Sm D2. (114 aa)
	A0A162TIG4	Uncharacterized protein. (182 aa)
	A0A162TJ34	Matrin-type domain-containing protein. (88 aa)
	A0A162TRS4	C2H2-type zinc finger transcription factor. (217 aa)
	A0A162TS38	WD_REPEATS_REGION domain-containing protein. (582 aa)
	A0A162TSJ7	RRM domain-containing protein. (324 aa)
	A0A162TW64	Sm domain-containing protein. (83 aa)
	A0A162U1W4	Small nuclear ribonucleoprotein Sm D3. (101 aa)
	A0A162U6L7	Ubiquitin-like domain-containing protein. (162 aa)
	A0A162UCH9	Sm domain-containing protein. (77 aa)
	A0A162UIL5	WD_REPEATS_REGION domain-containing protein. (360 aa)
	A0A162UNI8	CCHC-type zinc finger transcription factor. (321 aa)
	A0A162UP04	Uncharacterized protein. (786 aa)
	A0A162URN8	F-box domain-containing protein. (460 aa)
	A0A162UVW1	Nuclear cap-binding protein subunit 2. (218 aa)
	A0A162UWS7	CHHC U11-48K-type domain-containing protein. (251 aa)
	A0A162UZE8	Helicase_PWI domain-containing protein. (264 aa)
	A0A162V3A6	F-box domain-containing protein. (349 aa)
	A0A162V6T2	Uncharacterized protein. (147 aa)
	A0A162V9Z2	Uncharacterized protein. (667 aa)
	A0A162VAV6	MPN domain-containing protein. (2557 aa)
	A0A162WAA6	Uncharacterized protein. (209 aa)
	A0A162WEL2	Uncharacterized protein. (655 aa)
	A0A162WGT1	Uncharacterized protein. (254 aa)
	A0A162WUC2	FHA domain-containing protein. (146 aa)
	A0A162WWD6	RRM domain-containing protein. (161 aa)
	A0A162WYS6	RRM domain-containing protein. (389 aa)
	A0A162XHM3	WD_REPEATS_REGION domain-containing protein. (336 aa)
	A0A162XIN6	Uncharacterized protein. (264 aa)
	A0A162XQI6	Small nuclear ribonucleoprotein G. (76 aa)
	A0A162YGS8	Matrin-type domain-containing protein. (283 aa)
	A0A162YKD0	Uncharacterized protein. (674 aa)
	A0A162ZFV8	Uncharacterized protein. (607 aa)
	A0A162ZIE5	Uncharacterized protein. (266 aa)
	A0A162ZLU6	Uncharacterized protein. (110 aa)
	A0A162ZQZ9	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family. (152 aa)
	A0A162ZSG1	Uncharacterized protein; Belongs to the DEAD box helicase family. (513 aa)
	A0A162ZWF0	Uncharacterized protein. (1303 aa)
	A0A162ZYA7	LRRcap domain-containing protein. (249 aa)
	A0A162ZZU7	Tr-type G domain-containing protein. (981 aa)
	A0A163AC09	RRM domain-containing protein. (193 aa)
	A0A163ANB2	Uncharacterized protein. (439 aa)
	A0A163AR04	Uncharacterized protein. (1639 aa)
	LSM4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (135 aa)
	A0A163AYQ4	RRM domain-containing protein. (368 aa)
	A0A163B835	RRM domain-containing protein. (122 aa)
	A0A163BBS8	Uncharacterized protein. (407 aa)
	A0A163CS66	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (89 aa)
	A0A163CVV5	SFM domain-containing protein. (260 aa)
	A0A163DCS4	Uncharacterized protein. (1452 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. (137 aa)
	A0A163DTP0	Small nuclear ribonucleoprotein Sm D3. (117 aa)
	A0A163DZK5	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (87 aa)
	A0A163E4M4	Uncharacterized protein. (325 aa)
	A0A163E7C7	Uncharacterized protein. (1152 aa)
	A0A163E7E3	Uncharacterized protein. (306 aa)
	A0A163EQ32	MI domain-containing protein. (525 aa)
	A0A163ESU9	CCCH-type zinc finger transcription factor. (355 aa)
	A0A167J694	Uncharacterized protein; Belongs to the DEAD box helicase family. (613 aa)
	A0A167JBB7	RRM domain-containing protein. (155 aa)
	A0A167JC21	Uncharacterized protein. (742 aa)
	A0A167JC72	Sm domain-containing protein. (134 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (94 aa)
	A0A167JLM6	Uncharacterized protein. (114 aa)
	A0A167JXE1	Uncharacterized protein. (369 aa)
	A0A167K4X1	Uncharacterized protein. (446 aa)
	A0A167KDG4	Nop domain-containing protein. (446 aa)
	A0A167KJK7	Uncharacterized protein. (165 aa)
	A0A167KNG8	Uncharacterized protein. (248 aa)
	A0A167KR42	SF3b1 domain-containing protein. (1209 aa)
	A0A167KTV1	Uncharacterized protein. (801 aa)
	A0A167KW34	Uncharacterized protein. (477 aa)
	A0A167L0B2	Uncharacterized protein. (360 aa)
	A0A167L0X3	Uncharacterized protein. (858 aa)
	A0A167LDN3	PWI domain-containing protein. (238 aa)
	A0A167LF59	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (172 aa)
	A0A167LQM0	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (155 aa)
	A0A167M212	Cir_N domain-containing protein. (216 aa)
	A0A167M2C5	PPIase cyclophilin-type domain-containing protein. (335 aa)
	A0A167M8Y7	Uncharacterized protein. (698 aa)
	A0A167MBJ5	Slu7 domain-containing protein. (442 aa)
	A0A167MHB6	WD_REPEATS_REGION domain-containing protein. (317 aa)
	A0A167MID4	Uncharacterized protein. (268 aa)
	A0A167MJ23	WD_REPEATS_REGION domain-containing protein. (515 aa)
	A0A167MM66	Uncharacterized protein. (275 aa)
	A0A167MPY4	Homeodomain-like DNA binding domain-containing transcription factor. (810 aa)
	A0A167MT18	MPN domain-containing protein. (2555 aa)
	PRP4	Serine/threonine protein kinase Prp4; Belongs to the protein kinase superfamily. (342 aa)
	A0A167N0K9	Uncharacterized protein. (573 aa)
	A0A167N5W7	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (457 aa)
	A0A167NZG0	Uncharacterized protein. (226 aa)
	A0A167PML2	Uncharacterized protein; Belongs to the DEAD box helicase family. (740 aa)
	A0A167PMR4	Uncharacterized protein. (166 aa)
	A0A167PNK0	Ubiquitin-like domain-containing protein. (73 aa)
	A0A167PR85	Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family. (95 aa)
	A0A167PTA2	Uncharacterized protein. (519 aa)
	A0A167PUX8	C2H2-type zinc finger transcription factor. (324 aa)
	A0A167Q3B2	Uncharacterized protein. (598 aa)
	A0A167Q5H4	DUF1716 domain-containing protein. (628 aa)
	A0A167Q9N0	Tr-type G domain-containing protein. (1053 aa)
	A0A167QGU8	Uncharacterized protein. (498 aa)
	A0A167QHP6	Uncharacterized protein. (317 aa)
	A0A167QHQ7	SNRNP27 domain-containing protein. (102 aa)
	A0A167QP77	Cwf21 domain-containing protein. (141 aa)
	A0A167QQJ9	Matrin-type domain-containing protein. (236 aa)
	A0A167QS36	CPSF_A domain-containing protein. (1317 aa)
	A0A167QWU6	Uncharacterized protein. (693 aa)
	A0A167R2I8	Uncharacterized protein. (114 aa)
	A0A167R3P4	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (104 aa)
	A0A167R8M0	CCHC-type zinc finger transcription factor. (451 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A162N3L9	A0A162N4I1	A0A162N3L9	A0A162N4I1	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	Uncharacterized protein.	0.444
A0A162N3L9	A0A162N558	A0A162N3L9	A0A162N558	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	Uncharacterized protein.	0.698
A0A162N3L9	A0A162N8H3	A0A162N3L9	A0A162N8H3	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	Matrin-type domain-containing protein.	0.722
A0A162N3L9	A0A162N8W7	A0A162N3L9	A0A162N8W7	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	PSP domain-containing protein.	0.689
A0A162N3L9	A0A162NCR2	A0A162N3L9	A0A162NCR2	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	Helicase C-terminal domain-containing protein.	0.840
A0A162N3L9	A0A162NFX4	A0A162N3L9	A0A162NFX4	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	Uncharacterized protein.	0.444
A0A162N3L9	A0A162NGK1	A0A162N3L9	A0A162NGK1	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	Uncharacterized protein.	0.444
A0A162N3L9	A0A162NIJ6	A0A162N3L9	A0A162NIJ6	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	Sm domain-containing protein.	0.917
A0A162N3L9	A0A162NKQ8	A0A162N3L9	A0A162NKQ8	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	CCCH-type zinc finger transcription factor.	0.689
A0A162N3L9	A0A162PJI7	A0A162N3L9	A0A162PJI7	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	Uncharacterized protein.	0.998
A0A162N3L9	A0A162PKM0	A0A162N3L9	A0A162PKM0	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.495
A0A162N3L9	A0A162PQY1	A0A162N3L9	A0A162PQY1	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	Uncharacterized protein.	0.847
A0A162N3L9	A0A162PSU0	A0A162N3L9	A0A162PSU0	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	Sm domain-containing protein.	0.891
A0A162N3L9	A0A162PTI1	A0A162N3L9	A0A162PTI1	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	SKIP_SNW domain-containing protein.	0.998
A0A162N3L9	A0A162Q382	A0A162N3L9	A0A162Q382	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	Uncharacterized protein.	0.775
A0A162N3L9	A0A162Q3Y5	A0A162N3L9	A0A162Q3Y5	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.797
A0A162N3L9	A0A162QAC5	A0A162N3L9	A0A162QAC5	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	Splicing factor subunit; Belongs to the SF3B5 family.	0.689
A0A162N3L9	A0A162T021	A0A162N3L9	A0A162T021	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	RRM domain-containing protein.	0.689
A0A162N3L9	A0A162TBE7	A0A162N3L9	A0A162TBE7	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	CPSF_A domain-containing protein.	0.782
A0A162N3L9	A0A162THZ1	A0A162N3L9	A0A162THZ1	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.	Small nuclear ribonucleoprotein Sm D2.	0.922