(15 nodes) DNA damage checkpoint signaling network (Phycomyces blakesleeanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A162TGD1	Uncharacterized protein. (1515 aa)
	A0A162PVQ7	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (311 aa)
	A0A162VBI8	SLD3 domain-containing protein. (1003 aa)
	A0A162TLL5	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (309 aa)
	A0A167QV90	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (4023 aa)
	A0A167PUX8	C2H2-type zinc finger transcription factor. (324 aa)
	A0A167LCG4	MPN domain-containing protein. (452 aa)
	A0A167L451	Checkpoint protein; Belongs to the HUS1 family. (271 aa)
	A0A163D0E4	Uncharacterized protein. (172 aa)
	A0A162YL45	Uncharacterized protein. (1079 aa)
	A0A162YIW6	Uncharacterized protein. (172 aa)
	A0A162XTE5	Uncharacterized protein. (618 aa)
	A0A162N356	AAA domain-containing protein. (603 aa)
	Chk2	Checkpoint kinase 2-like protein. (559 aa)
	A0A162XJI2	Uncharacterized protein. (292 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A162N356	A0A162TGD1	A0A162N356	A0A162TGD1	AAA domain-containing protein.	Uncharacterized protein.	0.429
A0A162N356	A0A162XJI2	A0A162N356	A0A162XJI2	AAA domain-containing protein.	Uncharacterized protein.	0.996
A0A162N356	A0A162XTE5	A0A162N356	A0A162XTE5	AAA domain-containing protein.	Uncharacterized protein.	0.983
A0A162N356	A0A162YIW6	A0A162N356	A0A162YIW6	AAA domain-containing protein.	Uncharacterized protein.	0.989
A0A162N356	A0A167L451	A0A162N356	A0A167L451	AAA domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.989
A0A162N356	Chk2	A0A162N356	A0A162NH26	AAA domain-containing protein.	Checkpoint kinase 2-like protein.	0.726
A0A162TGD1	A0A162N356	A0A162TGD1	A0A162N356	Uncharacterized protein.	AAA domain-containing protein.	0.429
A0A162TGD1	A0A167QV90	A0A162TGD1	A0A167QV90	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.417
A0A162TGD1	Chk2	A0A162TGD1	A0A162NH26	Uncharacterized protein.	Checkpoint kinase 2-like protein.	0.461
A0A162VBI8	A0A167PUX8	A0A162VBI8	A0A167PUX8	SLD3 domain-containing protein.	C2H2-type zinc finger transcription factor.	0.718
A0A162XJI2	A0A162N356	A0A162XJI2	A0A162N356	Uncharacterized protein.	AAA domain-containing protein.	0.996
A0A162XJI2	A0A162YIW6	A0A162XJI2	A0A162YIW6	Uncharacterized protein.	Uncharacterized protein.	0.999
A0A162XJI2	A0A167L451	A0A162XJI2	A0A167L451	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.992
A0A162XJI2	Chk2	A0A162XJI2	A0A162NH26	Uncharacterized protein.	Checkpoint kinase 2-like protein.	0.716
A0A162XTE5	A0A162N356	A0A162XTE5	A0A162N356	Uncharacterized protein.	AAA domain-containing protein.	0.983
A0A162XTE5	A0A162YIW6	A0A162XTE5	A0A162YIW6	Uncharacterized protein.	Uncharacterized protein.	0.983
A0A162XTE5	A0A167L451	A0A162XTE5	A0A167L451	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.983
A0A162XTE5	Chk2	A0A162XTE5	A0A162NH26	Uncharacterized protein.	Checkpoint kinase 2-like protein.	0.677
A0A162YIW6	A0A162N356	A0A162YIW6	A0A162N356	Uncharacterized protein.	AAA domain-containing protein.	0.989
A0A162YIW6	A0A162XJI2	A0A162YIW6	A0A162XJI2	Uncharacterized protein.	Uncharacterized protein.	0.999