(22 nodes) Deoxyribonuclease activity network (Phycomyces blakesleeanus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	A0A167L655	3'-5' exonuclease domain-containing protein. (324 aa)
	A0A167QMF1	XPGN domain-containing protein. (430 aa)
	A0A167L866	Uncharacterized protein. (333 aa)
	A0A167LYT8	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (319 aa)
	A0A167MI72	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2213 aa)
	A0A167N6K0	DRMBL domain-containing protein. (356 aa)
	A0A167NIV2	Uncharacterized protein. (1091 aa)
	A0A167NX38	Uncharacterized protein. (270 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (375 aa)
	SLX1	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (277 aa)
	A0A167PRE9	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (411 aa)
	A0A167JHW9	ERCC4 domain-containing protein. (893 aa)
	A0A163D1U8	DNA polymerase. (1072 aa)
	A0A163B808	MKT1_C domain-containing protein. (306 aa)
	A0A163B0P3	ERCC4 domain-containing protein. (531 aa)
	A0A162YIR6	Endonuclease. (271 aa)
	A0A162V3B0	Uncharacterized protein. (311 aa)
	A0A162UFV0	POLIIIAc domain-containing protein. (423 aa)
	A0A162T215	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family. (392 aa)
	A0A162Q4N2	XPGI domain-containing protein. (152 aa)
	A0A162PVA1	AAA_12 domain-containing protein. (1367 aa)
	A0A162PH25	Endonuclease. (314 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A162PH25	A0A162Q4N2	A0A162PH25	A0A162Q4N2	Endonuclease.	XPGI domain-containing protein.	0.475
A0A162PH25	A0A167QMF1	A0A162PH25	A0A167QMF1	Endonuclease.	XPGN domain-containing protein.	0.475
A0A162PH25	FEN1	A0A162PH25	A0A167P3U0	Endonuclease.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.606
A0A162PVA1	A0A162Q4N2	A0A162PVA1	A0A162Q4N2	AAA_12 domain-containing protein.	XPGI domain-containing protein.	0.940
A0A162PVA1	A0A162T215	A0A162PVA1	A0A162T215	AAA_12 domain-containing protein.	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family.	0.917
A0A162PVA1	A0A162V3B0	A0A162PVA1	A0A162V3B0	AAA_12 domain-containing protein.	Uncharacterized protein.	0.971
A0A162PVA1	A0A163B0P3	A0A162PVA1	A0A163B0P3	AAA_12 domain-containing protein.	ERCC4 domain-containing protein.	0.866
A0A162PVA1	A0A163D1U8	A0A162PVA1	A0A163D1U8	AAA_12 domain-containing protein.	DNA polymerase.	0.902
A0A162PVA1	A0A167JHW9	A0A162PVA1	A0A167JHW9	AAA_12 domain-containing protein.	ERCC4 domain-containing protein.	0.815
A0A162PVA1	A0A167L655	A0A162PVA1	A0A167L655	AAA_12 domain-containing protein.	3'-5' exonuclease domain-containing protein.	0.997
A0A162PVA1	A0A167MI72	A0A162PVA1	A0A167MI72	AAA_12 domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.868
A0A162PVA1	A0A167NIV2	A0A162PVA1	A0A167NIV2	AAA_12 domain-containing protein.	Uncharacterized protein.	0.911
A0A162PVA1	A0A167NX38	A0A162PVA1	A0A167NX38	AAA_12 domain-containing protein.	Uncharacterized protein.	0.773
A0A162PVA1	A0A167QMF1	A0A162PVA1	A0A167QMF1	AAA_12 domain-containing protein.	XPGN domain-containing protein.	0.940
A0A162PVA1	FEN1	A0A162PVA1	A0A167P3U0	AAA_12 domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.940
A0A162PVA1	SLX1	A0A162PVA1	A0A167PH33	AAA_12 domain-containing protein.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	0.815
A0A162Q4N2	A0A162PH25	A0A162Q4N2	A0A162PH25	XPGI domain-containing protein.	Endonuclease.	0.475
A0A162Q4N2	A0A162PVA1	A0A162Q4N2	A0A162PVA1	XPGI domain-containing protein.	AAA_12 domain-containing protein.	0.940
A0A162Q4N2	A0A162T215	A0A162Q4N2	A0A162T215	XPGI domain-containing protein.	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family.	0.952
A0A162Q4N2	A0A162V3B0	A0A162Q4N2	A0A162V3B0	XPGI domain-containing protein.	Uncharacterized protein.	0.798