(57 nodes) Regulation of actin cytoskeleton organization network (Phycomyces blakesleeanus)

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	A0A162NDJ2	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	A0A162NKI0	Coronin; Belongs to the WD repeat coronin family. (434 aa)
	A0A162PPE8	Uncharacterized protein. (203 aa)
	A0A162PR44	CigA protein-like protein. (526 aa)
	A0A162PSR0	Uncharacterized protein. (1285 aa)
	A0A162PZQ3	Uncharacterized protein. (192 aa)
	A0A162Q001	Uncharacterized protein. (367 aa)
	A0A162Q3J3	Adenylyl cyclase-associated protein; Belongs to the CAP family. (482 aa)
	A0A162TB98	Uncharacterized protein. (650 aa)
	A0A162TTW1	Uncharacterized protein. (199 aa)
	A0A162U0I2	LIM zinc-binding domain-containing protein. (71 aa)
	A0A162U0Q5	Zn(2)-C6 fungal-specific transcription factor. (363 aa)
	A0A162U1U9	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (278 aa)
	A0A162U522	Uncharacterized protein. (576 aa)
	A0A162U9G3	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (270 aa)
	A0A162UGK7	GBD/FH3 domain-containing protein. (481 aa)
	A0A162UH90	ADF-H domain-containing protein. (149 aa)
	A0A162WMA6	ADF-H domain-containing protein. (138 aa)
	A0A162XXC3	GBD/FH3 domain-containing protein. (229 aa)
	A0A162Y7E1	Ras-GAP domain-containing protein. (799 aa)
	A0A163A6P0	Uncharacterized protein. (195 aa)
	A0A163AV65	Uncharacterized protein. (209 aa)
	A0A163CXH1	Uncharacterized protein. (404 aa)
	A0A163D646	Ras-GAP domain-containing protein. (803 aa)
	A0A167JES7	SH3 domain-containing protein. (354 aa)
	A0A167JHG0	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (173 aa)
	A0A167JJS4	Uncharacterized protein. (187 aa)
	A0A167JLD9	Uncharacterized protein. (452 aa)
	A0A167JX85	CigA protein-like protein. (519 aa)
	A0A167JXY3	Ras-GAP domain-containing protein. (821 aa)
	A0A167JYN6	Uncharacterized protein. (463 aa)
	A0A167K2X0	Uncharacterized protein. (153 aa)
	A0A167K3C2	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (155 aa)
	A0A167KCV4	Uncharacterized protein. (195 aa)
	A0A167L8B6	PH domain-containing protein. (1355 aa)
	A0A167L9G3	Uncharacterized protein. (347 aa)
	A0A167LA54	Uncharacterized protein. (78 aa)
	A0A167LZG8	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (372 aa)
	A0A167MHD2	GBD/FH3 domain-containing protein. (814 aa)
	A0A167MSP2	Uncharacterized protein. (1053 aa)
	A0A167MU57	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
	A0A167NAD1	WD_REPEATS_REGION domain-containing protein. (327 aa)
	A0A167NUA4	C2H2-type zinc finger transcription factor. (214 aa)
	A0A167NXF6	N-acetyltransferase domain-containing protein. (179 aa)
	A0A167P5K2	AIP3 domain-containing protein. (656 aa)
	A0A167P605	AIP3 domain-containing protein. (638 aa)
	A0A167P7N5	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (172 aa)
	A0A167P9Z4	Homeodomain-like DNA binding domain-containing transcription factor. (262 aa)
	A0A167PQS7	Uncharacterized protein. (589 aa)
	A0A167PZ12	Uncharacterized protein. (393 aa)
	A0A167Q2N3	Uncharacterized protein. (161 aa)
	A0A167Q9I4	Uncharacterized protein. (442 aa)
	A0A167QDB4	CRIB domain-containing protein. (180 aa)
	A0A167QF45	SH3 domain-containing protein. (276 aa)
	A0A167QFP2	WD_REPEATS_REGION domain-containing protein. (610 aa)
	A0A167QIW4	Uncharacterized protein. (193 aa)
	A0A167QPD8	Uncharacterized protein. (320 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A162NDJ2	A0A162NKI0	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Coronin; Belongs to the WD repeat coronin family.	0.487
A0A162NDJ2	A0A162PPE8	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.629
A0A162NDJ2	A0A162PR44	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	CigA protein-like protein.	0.566
A0A162NDJ2	A0A162PSR0	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.900
A0A162NDJ2	A0A162PZQ3	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.650
A0A162NDJ2	A0A162Q001	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.574
A0A162NDJ2	A0A162Q3J3	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Adenylyl cyclase-associated protein; Belongs to the CAP family.	0.938
A0A162NDJ2	A0A162TTW1	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.650
A0A162NDJ2	A0A162U1U9	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.517
A0A162NDJ2	A0A162U522	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.540
A0A162NDJ2	A0A162U9G3	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.699
A0A162NDJ2	A0A162UGK7	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	GBD/FH3 domain-containing protein.	0.900
A0A162NDJ2	A0A162XXC3	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	GBD/FH3 domain-containing protein.	0.900
A0A162NDJ2	A0A163A6P0	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.650
A0A162NDJ2	A0A163AV65	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.650
A0A162NDJ2	A0A167JX85	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	CigA protein-like protein.	0.566
A0A162NDJ2	A0A167JYN6	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.566
A0A162NDJ2	A0A167K2X0	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.496
A0A162NDJ2	A0A167KCV4	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.650
A0A162NDJ2	A0A167LZG8	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family.	0.523